8. Bibliography:

8.1. Бочков Н.П. Клиническая генетика. М., 2004.

8.2. Генетика. Под ред. Иванова В.И. М., 2006.

8.3. Гинтер Е.К. Медицинская генетика. М., 2003.

8.4. Жимулев И.Ф. Общая и молекулярная генетика. Новосибирск, 2003.

8.5. Тейлор Д., Грин Н., Стаут У. Биология. М., 2002.

9. Check:

9.1. List the main types of sex determination.

9.2. What does the Y-chromosome role in sex determination consist in?

9.3. What is the role of autosomal genes in sex determination?

9.4. What factors influence the secondary sex determination?

9.5. What pathological conditions are formed at disturbance of sex determination?

1. Theme #9. Molecular and genetic mechanisms of aging

2. The aim: to study the molecular and genetic mechanisms of aging

3. The tasks:

3.1 Genetics of aging.

3.2 Aging mechanism.

3.3 To tell about display of aging on molecular and cellular level.

3.4 Modern aging theories.

4. Performance form: presentation compiling.

The structure of abstract work:

1) the title page (made up in due form);

2) the table of contents (consecutive statement with indication of the main sections page numbers);

3) introduction (substantiation of the researched problem, its importance and urgency; determination of the aims and tasks of work);

4) the main part (each section should reveal evidentially a particular problem or one of its aspects, be logic continuation of the previous material; tables, schemes, diagrams, figures can be presented in this section or they can be executed as annex to abstract work);

5) conclusion (the results are summed up, the deductions are formulated and recommendations are suggested);

6) the list of bibliography (made up in due form).

5. Requirements to presentation making up:

а) a presentation should be made on the basis of “Microsoft Power Point” program;

b) the number of slides should be no more than 10-15;

c) slides shouldn't be loaded by a text material;

d) the list of bibliography should correspond to the references used.

6. Deadline: before the midterm control on the chapter “Fundamentals of general genetics”.

7. Criteria of assessment: - 100 points at maximum that corresponds to 100%

8. Bibliography:

8.1. Бочков Н.П. Клиническая генетика. М., 2004.

8.2. Введение в молекулярную медицину. Под ред. Пальцева М.А. М., 2004.

8.3. Гинтер Е.К. Медицинская генетика. М., 2003.

8.4. Лильин Е.Т. и др. Генетика для врачей. М., 1990.

8.5. Медицинская биология и генетика. Куандыкова Е.У. А., 2004.

8.6. Иванов В.И. и др. Генетика. М., 2006, с.430-601.

8.7. Заяц Р.Г., Бутвиловский В.Э., Рачковская И.В., Давыдов В.В. Общаяимедицинская генетика. Ростов-на-Дону. 2002.

8.8. Умнов Д.Е. Медицинская генетика. М., 2005.

8.9. Хандогина Е.К. и др. Основы медицинской генетики. М., 2004.

9. Check:

9.1 Vital cases which influence the aging process.

9.2 Changes in organs in the course of aging.

1. Theme #10. Stem cells and their medical value

2. The aim: to form at students modern ideas of biology of stem cells and possibility of their use in clinical practice.

3. The tasks:

3.1. The history of stem cells studying (SC).

3.2. The concept of stem cells.

3.3. Embryonic stem cells.

3.4. Stem cells of adult organisms.

3.5. Ways of stem cells production.

3.6. Application of stem cells in clinical practice.

3.7. Achievements, prospects in stem cells studying.

4. Performance form: abstract work.

5. Performance criteria:

а) studying and selection of recent literary sources;

b) information processing and systematization;

c) plan designing;

d) bibliography compiling;

e) abstract and/or project work making up.

The structure of abstract work:

1) the title page (made up in due form);

2) the table of contents (consecutive statement with indication of the main sections page numbers);

3) introduction (substantiation of the researched problem, its importance and urgency; determination of the aims and tasks of work);

4) the main part (each section should reveal evidentially a particular problem or one of its aspects, be logic continuation of the previous material; tables, schemes, diagrams, figures can be presented in this section or they can be executed as annex to abstract work);

5) conclusion (the results are summed up, the deductions are formulated and recommendations are suggested);

6) the list of bibliography (made up in due form).

Requirements to abstract work design:

а) the volume of abstract work should not exceed 10-15 printing pages (annexes are not included into a paper volume);

b) a text of abstract work should be carefully edited and grammatically verified;

c) references should be presented in numbers, corresponding to the number in the list of bibliography;

d) the list of bibliography should be at the end of a text according to order of appearance.

6. Deadline: before the midterm control on the chapter “Fundamentals of general genetics”.

7. Criteria of assessment: - 100 points at maximum that corresponds to 100%

8. Bibliography:

8.1. Архив патологии, № 4, 2002.

8.2. Введение в молекулярную медицину. Под ред. Пальцева М.А. М., 2003.

8.3. Владимирская Е.Б., Румянцева А.Г. // Вопросы гематологии, онкологии и иммунопатологии в педиатрии. М., 2002, № 1.

8.4. Клиническая лабораторная диагностика, № 4, 2006.

8.5. Клиническая медицина, № 1, 2004.

8.6. Основы общей и медицинской генетики. Куандыкова Е.У., А., 2009.

9. Check:

9.1. Stem cells properties: advantages and problems of their use in medicine.

9.2. Nomenclature of stem cells: embryonic stem cells (ESC), hemopoietic stem cells (HSC).

9.3. Stem cells flexibility.

1. Theme #11. Gene technologies in medicines production

2. The aim: to form at students ideas of contemporary methods of medicines development and production on the basis of genetically engineered technology application.

3. The tasks:

3.1. Synthesis of medicines with gene technologies application.

3.2. Biotechnological synthesis of medicines.

3.3. Methodology of search of new medicines, products of biotechnology, genetic engineering in pathological states.

4. Performance form: presentation compiling.

5. Performance criteria:

а) studying and selection of recent literary sources;

b) information processing and systematization;

c) plan designing;

d) bibliography compiling;

e) abstract and/or project work making up.

The structure of abstract work:

1) the title page (made up in due form);

2) the table of contents (consecutive statement with indication of the main sections page numbers);

3) introduction (substantiation of the researched problem, its importance and urgency; determination of the aims and tasks of work);

4) the main part (each section should reveal evidentially a particular problem or one of its aspects, be logic continuation of the previous material; tables, schemes, diagrams, figures can be presented in this section or they can be executed as annex to abstract work);

5) conclusion (the results are summed up, the deductions are formulated and recommendations are suggested);

6) the list of bibliography (made up in due form).

Requirements to presentation making up:

а) a presentation should be made on the basis of “Microsoft Power Point” program;

b) the number of slides should be no more than 10-15;

c) a presentation should be done skillfully, be available to perception, slides shouldn't be loaded by a text material;

d) the list of bibliography should be presented on the last slide.

6. Deadline: before the midterm control on the chapter “Fundamentals of general genetics”.

7. Criteria of assessment: - 100 points at maximum that corresponds to 100%