Specialty-general medicine methodology recommendation for independent work teacher-led
COURSE:1
DISIPLINE: MOLECULAR BIOLOGY AND MEDICINE GENETICS
COMPILERS:TEACHERS OF DEPARTMENT
2012
Discussed and approved by meeting from «12 of april» 2012 protocol №15
Head of department, professor Kuandykov E.U.
Lesson number 1
Theme: Molecular and genetic mechanisms of regulation of a mitotic cycle
2. Purpose: To create at students of knowledge and understanding of essence of regulation of a mitotic cycle, as bases of existence and development of live organisms.
3. Problems of training:
- studying of molecular mechanisms of regulation of process of cell fission;
- studying a role of the genes participating in process of regulation and control of a mitotic cycle;
- studying of the reasons and mechanisms of violation of cellular division;
- studying of medical consequences of violations of cellular division.
4. Main questions of a subject:
4.1. Mechanisms of genetic regulation of a mitotic cycle.
4.2. Mechanisms of genetic control of a mitotic cycle.
4.3. Reasons and mechanisms of violation of a mitotic cycle.
4.4. Medical consequences of violations of a mitotic cycle.
5. Training methods: the combined method of training (conversation, a sketch of schemes, filling of tables).
6. Literature:
6.1. Muminov T.A., Kuandykov E.U. Bases of molecular biology (course of lectures).
6.2. Almaty, 2007, page 116-131.
6.3. Mushkambarov N. N., Kuznetsov S. L. Molecular biology. M, 2003, page 413-443.
6.4. Faller D. M., Shields D. Molecular cytobiology. M, 2006, page 129-144.
The additional:
6.1. Medical biology and genetics. The manual under the editorship of prof. Kuandykov E.U. Almaty, 2004, page 53-54
7. Control:
7.1. An assessment of competences – knowledge.
7.1.1. Oral poll concerning a subject.
7.1.2. Test control – 3 options on 10 questions.
7.2. An assessment of competences – practical skills.
7.2.1. To represent and explain a role of ciclyne and ciclyne - dependent kinases in regulation of a mitotic cycle.
7.2.2. To represent and explain a role of verifying points in control of a mitotic cycle.
7.2.3. Sketch of schemes
- Specify mitogenny incentives and inhibitors, and also the ciclyne - dependent kinases defining different phases of a cellular cycle.
Lesson number 1
1. Title: Apoptosis
2. Aims: To generate in students the knowledge and understanding the essence and value apoptosis, its role in insuring normal vital functions and development of pathological processes
3. Learning objectives:
- research on the causes and mechanisms of apoptosis.
- study of genetic, biochemical and morphological changes in cells to apoptosis.
- study of the causes and mechanisms of violations of apoptosis and its importance in the genesis and evolution of human pathologies.
4. Methods of study: combined method of training (interview, filling out tables, the job skills.)
5. Key questions the theme:
5.1. Apoptosis, definition.
5.2. Causes of apoptosis.
5.3. Stages of development of apoptosis.
5.4. Genetic control of apoptosis.
5.5. The medical significance of apoptosis.
6. Handout: test questions.
7. References:
The main:
7.1. Biology. Edited by VN Yarygin. M: 2001, Part 1, pp.347-351.
7.2. Genetics. Under Ivanov VI editor M:,2006, pp.557-568.
7.3. Kuandykova E.W, Muminov T.A. Fundamentals of Molecular Biology A.,2007,pp.132-141.
7.4.Mushkambarov N. Kuznecov S.L. "Molecular Biology" M: 2003. pp.443-501
7.5 Fuller, DM, Dennis Shilds.Molekulyarnaya cell biology.2006,pp134-137.
Additional:
7.1. Zhymulev I.F. Basis and Molecular genetics. 2006 pp.387-389.
7.2. Pehove A.P. Biology and general genetics. Moscow,2006, pp.640.
7.3.Genomica – Medicine. Edited by Ivanova V.I.M., 2006, pp.392.
7.4. Kazymbet P.K. Myroedova E.P. Biology. Parts I,II. Astana, 2006,2007.
7.5. Konichev A.S. Molecular biology.M.,2005, p397.