8.1.Control:
8.1. Rating of competences - knowledge
8.1.1. Quizzes on topics
8.1.2. Test Control-12 variants with 10 questions
8.2. Rating of competence skills.
8.2.1. The site of a DNA molecule encoding a polypeptide has the following order of nitrogenous bases: AAAATSTSAAAATATSTTATSTTATATSGA Determine how many codons that contains a DNA fragment Why?
8.2.2. A fragment of the DNA chain has the following sequence: TSGAAATSTAGGTSTATTSAATGTSAGT. How many polypeptide chains are encoded and why?
8.2.3. Studies have shown that 34% of the total number of nucleotides of the RNA, and accounts for guanine, uracil at 18%, 28% cytosine and 20% for adenine. Determine the percentage composition of the nitrogenous bases of double-stranded DNKb replica of which is indicated, and RNA.
8.2.4.
What
is
the
length of the
portion
of
DNA
encoding
the
insulin-bull,
if
it is known
that
the
insulin
molecule
has
51
amino acids,
and the distance between
two adjacent
nucleotides
in
DNA
is
34
*
.
8.2.5. The average molecular weight of about 110 amino acids, and nucleotides 300. What's harder: a protein or gene?
8.2.6.Nucleic
acid
has
a molecular
mass
of
.
About
how many
proteins
are
encoded
in
it,
if
we assume
that
a typical
protein
consists
iz400
monomers
and
the
molecular weight of
300
nucleotides..
8.2.7. The site of a DNA molecule encoding a portion of the polypeptide has the following structure: ATSTSATAGTTSTSAAAGA. Determine the sequence of amino acids in a polypeptide
8.2.8. The sequence of nucleotides in a gene: TATSGGTTGAAAAGTTSTGATTST encodes amino acids, meth, hair dryer, arg. Set the exons and introns, i- RNA.
8.2.Alpha9.In preparations of DNA isolated from cells of tubercle bacilli, the content of adenine was 15.1% of the total number of bases. Determine the approximate number of guanine, thymine and cytosine in the DNA
8.2.10. In the analysis of the nucleotide composition of DNA of the bacteriophage was observed following the quantitative ratio of nitrogenous bases: A, 23%, 21% T, T-36% C-20%. How can we explain the reason that in this case is not observed the principle of equivalence established by Chargaff?
8.2.11. Determine how many triplets of mRNA contain information about the polypeptide consisting of 900 amino acid residues, and what is the number of nucleotides in the appropriate section of the coding strand of DNA.
8.2.12. Calculate the number of nucleosomes that are required for packaging DNKgena encoding a protein of medium size, consisting of 400 amino acid residues. The value of a piece of NK nucleosomes can be considered equal to 200 pairs of nucleotides.
Lesson 9
Theme: Genetic Apparatus of the Cell
Object: Form students’ knowledge ofthe structural and functional organization of cell genetic material.
Educational Tasks:
to study the role of genetic material of the cell as the basis of organisms’ vital activity;
to study peculiarities of the structural and functional organization of genetic materialof the cell localized in the nucleus and cytoplasm;
to study molecular mechanisms of formation of different levels of the structural and functional organization of cell genetic material based on its compacting;
to form students’ understanding of the essence of the karyotype and its significance in diagnostics of chromosome diseases.