7. Control:

1. Evaluation of competence – knowledge

1. Filling-in tables:

Table 1

Draw up a table of possible combinations of sex chromosomes in a human zygote, analyze each variant and determine of possible number of Barr’s bodies (sex chromatin):

	X	XX	0
X
Y
XY
0

Table 2

Impairment related to different types of human aneuploidy

Disease name	Chromosome	Etiology	Pathogenesis	Manifestations
2.1. Autosomal syndromes
Down’s syndrome
Edwards’ syndrome
Patau’s syndrome
Down’s translocation chromosome
Cat’s cry syndrome
2.2. Gonosomic syndromes
Turner syndrome
Kleinfelter’s syndrome
X trisomy

2. Evaluation of competence – practical skills

   1. Work in a small group – role play “Doctor – Patient” (is carried out according to the methodical recommendation developed for such work)

Lesson 6

1. Theme: Human Hereditary Diseases. MonogenicMendelian Diseases

2. Object:

• form students’ knowledge of gene diseases and their classification;

• explain genetic mechanisms of development of human genic diseases;

• develop communicative skills during analysis of the etiology of human genic pathologies and their classification;

• develop communicative skills in the process of solution of typical situation problems and filling-in didactic tables;

• form practical skills in the process of role plays.

3. Educational Tasks:

• familiarize the students with the principal types of inheritance of genic disease;

• teach students to differ clinical manifestations of genic diseases;

• teach students to apply the knowledge received in their practical activity and in the process of role plays;

• adopt practical skills of doctor’s thinking, principles of psychological assessment of the state of patients with hereditary diseases and members of their families, the ability to correctly build relations with them.