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[1]Эффект ограниченного количества делений нормальных (неопухолевых) клеток многоклеточного организма был обнаружен в 1961 году Леонардом Хейфликом и Полом Мурхедом. До этого на основе ошибочных экспериментов французского биолога Алексиса Карреля в науке господствовало представление о том, что клетки имеют неограниченный потенциал деления. Для человеческих клеток предел Хейфлика составляет от 52 до 60 делений.

[2]Skunk Works («Мастерская скунса», или в другом варианте «Дело дрянь») — секретное подразделение аэрокосмического концерна Lockheed (ныне Lockheed Martin), созданное для разработки перспективных проектов.

[3]Антибиотик, продуцируемый почвенными бактериями

Streptomyces hygroscopicus. В медицине используется как иммунодепрессант, снижающий риск отторжения органов, в частности почек, при трансплантации. Исследования, ведущиеся с 2006 года, показывают, что рапамицин увеличивает продолжительность жизни у целого ряда организмов.

[4]Стоит отметить, что проект все еще продолжается, и исследователями Центра открытой науки проверены результаты 50 экспериментов, опубликованных в 23 работах в области онкологии в период с 2010 по 2012 год (https://www.cos.io/rpcb?hs).

[5]Шапероны — семейство специализированных белков, которые связываются с неустойчивыми формами других белков, способствуя правильной их сборке и укладке (фолдингу). — Прим. ред.

[6]ЮНЕСКО (United Nations Educational, Scientific and Cultural Organization) — специализированное учреждение ООН по вопросам

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образования, науки и культуры, созданное в ноябре 1945 года.

[7]Психологическая резилентность — врожденное динамическое свойство личности, лежащее в основе способности преодолевать стрессы и трудные периоды конструктивным путем. — Прим. ред.

[8]Мультицентровое исследование — исследование, проводимое по единой методике и программе одновременно в нескольких лечебных учреждениях.

[9]Дженерик — лекарственный препарат, в основе которого присутствует тот же активный фармацевтический ингредиент, что и в оригинальном средстве.

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В книге упоминаются социальные сети Instagram и/или Facebook, принадлежащие компании Meta Platforms Inc., деятельность которой по реализации соответствующих продуктов на территории Российской Федерации запрещена.

Редакторы Анна Киреева, Сырлыбай Айбусинов

Главный редактор С. Турко Руководитель проекта О. Равданис

Художественное оформление и макет Ю. Буга

Корректоры Е. Аксёнова, А. Кондратова

Компьютерная верстка М. Поташкин Иллюстрация на обложке shutterstock.com

©Пётр Федичев, 2023

©ООО «Альпина Паблишер», 2023

Федичев П.

Взломать старение: Почему теперь мы сможем жить дольше / Пётр Олегович Федичев: М.: Альпина Паблишер, 2023.

ISBN 978-5-9614-8400-7

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