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390 Section II / General Surgery

 

Grey Turner’s sign

Ecchymosis or discoloration of the

 

flank in patients with retroperitoneal

 

hemorrhage from dissecting blood from

 

the retroperitoneum (Think: Grey

 

TURNer TURN side to side flank

 

[side] hematoma)

Fox’s sign

Ecchymosis of the inguinal ligament

 

from blood tracking from the

 

retroperitoneum and collecting at the

 

inguinal ligament

What are the significant lab

Increased amylase/lipase

values?

Decreased Hct

 

Decreased calcium levels

What radiologic test should

CT scan with IV contrast

be performed?

 

PANCREATIC ABSCESS

 

 

 

What is it?

Infected peripancreatic purulent fluid

 

collection

What are the signs/

Fever, unresolving pancreatitis, epigastric

symptoms?

mass

What radiographic tests

Abdominal CT with needle aspiration S

should be performed?

send for Gram stain/culture

What are the associated lab

Positive Gram stain and culture of

findings?

bacteria

Which organisms are found

Gram negative (most common):

in pancreatic abscesses?

Escherichia coli, Pseudomonas,

 

Klebsiella

 

Gram positive: Staphylococcus aureus,

 

Candida

What is the treatment?

Antibiotics and percutaneous drain

 

placement or operative débridement

 

and placement of drains

 

Chapter 55 / Pancreas 391

PANCREATIC NECROSIS

 

 

 

What is it?

Dead pancreatic tissue, usually following

 

acute pancreatitis

How is the diagnosis made?

Abdominal CT with IV contrast; dead

 

pancreatic tissue does not take up IV

 

contrast and is not enhanced on CT scan

 

(i.e., doesn’t “light up”)

What is the treatment:

 

 

Sterile?

Medical management

 

Suspicious of infection?

CT-guided FNA

 

Toxic, hypotensive?

Operative débridement

 

PANCREATIC PSEUDOCYST

 

 

What is it?

Encapsulated collection of pancreatic

 

fluid

 

 

Non-communicating

 

 

pseudocyst

 

 

 

‘07

 

f

 

hr

 

Communicating

pseudocyst

What makes it a “pseudo” cyst?

What is the incidence?

What are the associated risk factors?

What is the most common cause of pancreatic pseudocyst in the United States?

Wall is formed by inflammatory fibrosis, NOT epithelial cell lining

1 in 10 after alcoholic pancreatitis

Acute pancreatitis chronic pancreatitis from alcohol

Chronic alcoholic pancreatitis

392 Section II / General Surgery

What are the symptoms?

What are the signs?

What lab tests should be performed?

What are the diagnostic findings?

What is the differential diagnosis of a pseudocyst?

What are the possible complications of a pancreatic pseudocyst?

What is the treatment?

What is the waiting period before a pseudocyst should be drained?

What percentage of pseudocysts resolve spontaneously?

What is the treatment for pseudocyst with bleeding into cyst?

Epigastric pain/mass Emesis

Mild fever Weight loss

Note: Should be suspected when a patient with acute pancreatitis fails to resolve pain

Palpable epigastric mass, tender epigastrium, ileus

Amylase/lipase

Bilirubin

CBC

Lab—High amylase, leukocytosis, high bilirubin (if there is obstruction)

U/S—Fluid-filled mass CT—Fluid-filled mass, good for showing

multiple cysts ERCP—Radiopaque contrast material

fills cyst if there is a communicating pseudocyst (i.e., pancreatic duct communicates with pseudocyst)

Cystadenocarcinoma, cystadenoma

Infection, bleeding into the cyst, fistula, pancreatic ascites, gastric outlet obstruction, SBO, biliary obstruction

Drainage of the cyst or observation

It takes 6 weeks for pseudocyst walls to “mature” or become firm enough to hold sutures and most will resolve in this period of time if they are going to

50%

Angiogram amd embolization

 

Chapter 55 / Pancreas 393

What is the treatment for

Percutaneous external drainage/

pseudocyst with infection?

IV antibiotics

What size pseudocyst should

Most experts say:

be drained?

Pseudocysts larger than 5 cm have a

 

small chance of resolving and have

 

a higher chance of complications

 

Calcified cyst wall

 

Thick cyst wall

What are three treatment options for pancreatic pseudocyst?

What are the surgical options for the following conditions:

Pseudocyst adherent to the stomach?

Pseudocyst adherent to the duodenum?

Pseudocyst not adherent to the stomach or duodenum?

Pseudocyst in the tail of the pancreas?

What is an endoscopic option for drainage of a pseudocyst?

1.Percutaneous aspiration/drain

2.Operative drainage

3.Transpapillary stent via ERCP (pseudocyst must communicate with pancreatic duct)

Cystogastrostomy (drain into the stomach)

Cystoduodenostomy (drain into the duodenum)

Roux-en-Y cystojejunostomy (drain into the Roux limb of the jejunum)

Resection of the pancreatic tail with the pseudocyst

Endoscopic cystogastrostomy

What must be done during a Biopsy of the cyst wall to rule out a cystic surgical drainage procedure carcinoma (e.g., cystadenocarcinoma) for a pancreatic pseudocyst?

What is the most common Massive hemorrhage into the pseudocyst cause of death due to

pancreatic pseudocyst?

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