- •Table of Contents
- •Copyright
- •Dedication
- •Introduction to the eighth edition
- •Online contents
- •List of Illustrations
- •List of Tables
- •1. Pulmonary anatomy and physiology: The basics
- •Anatomy
- •Physiology
- •Abnormalities in gas exchange
- •Suggested readings
- •2. Presentation of the patient with pulmonary disease
- •Dyspnea
- •Cough
- •Hemoptysis
- •Chest pain
- •Suggested readings
- •3. Evaluation of the patient with pulmonary disease
- •Evaluation on a macroscopic level
- •Evaluation on a microscopic level
- •Assessment on a functional level
- •Suggested readings
- •4. Anatomic and physiologic aspects of airways
- •Structure
- •Function
- •Suggested readings
- •5. Asthma
- •Etiology and pathogenesis
- •Pathology
- •Pathophysiology
- •Clinical features
- •Diagnostic approach
- •Treatment
- •Suggested readings
- •6. Chronic obstructive pulmonary disease
- •Etiology and pathogenesis
- •Pathology
- •Pathophysiology
- •Clinical features
- •Diagnostic approach and assessment
- •Treatment
- •Suggested readings
- •7. Miscellaneous airway diseases
- •Bronchiectasis
- •Cystic fibrosis
- •Upper airway disease
- •Suggested readings
- •8. Anatomic and physiologic aspects of the pulmonary parenchyma
- •Anatomy
- •Physiology
- •Suggested readings
- •9. Overview of diffuse parenchymal lung diseases
- •Pathology
- •Pathogenesis
- •Pathophysiology
- •Clinical features
- •Diagnostic approach
- •Suggested readings
- •10. Diffuse parenchymal lung diseases associated with known etiologic agents
- •Diseases caused by inhaled inorganic dusts
- •Hypersensitivity pneumonitis
- •Drug-induced parenchymal lung disease
- •Radiation-induced lung disease
- •Suggested readings
- •11. Diffuse parenchymal lung diseases of unknown etiology
- •Idiopathic pulmonary fibrosis
- •Other idiopathic interstitial pneumonias
- •Pulmonary parenchymal involvement complicating systemic rheumatic disease
- •Sarcoidosis
- •Miscellaneous disorders involving the pulmonary parenchyma
- •Suggested readings
- •12. Anatomic and physiologic aspects of the pulmonary vasculature
- •Anatomy
- •Physiology
- •Suggested readings
- •13. Pulmonary embolism
- •Etiology and pathogenesis
- •Pathology
- •Pathophysiology
- •Clinical features
- •Diagnostic evaluation
- •Treatment
- •Suggested readings
- •14. Pulmonary hypertension
- •Pathogenesis
- •Pathology
- •Pathophysiology
- •Clinical features
- •Diagnostic features
- •Specific disorders associated with pulmonary hypertension
- •Suggested readings
- •15. Pleural disease
- •Anatomy
- •Physiology
- •Pleural effusion
- •Pneumothorax
- •Malignant mesothelioma
- •Suggested readings
- •16. Mediastinal disease
- •Anatomic features
- •Mediastinal masses
- •Pneumomediastinum
- •Suggested readings
- •17. Anatomic and physiologic aspects of neural, muscular, and chest wall interactions with the lungs
- •Respiratory control
- •Respiratory muscles
- •Suggested readings
- •18. Disorders of ventilatory control
- •Primary neurologic disease
- •Cheyne-stokes breathing
- •Control abnormalities secondary to lung disease
- •Sleep apnea syndrome
- •Suggested readings
- •19. Disorders of the respiratory pump
- •Neuromuscular disease affecting the muscles of respiration
- •Diaphragmatic disease
- •Disorders affecting the chest wall
- •Suggested readings
- •20. Lung cancer: Etiologic and pathologic aspects
- •Etiology and pathogenesis
- •Pathology
- •Suggested readings
- •21. Lung cancer: Clinical aspects
- •Clinical features
- •Diagnostic approach
- •Principles of therapy
- •Bronchial carcinoid tumors
- •Solitary pulmonary nodule
- •Suggested readings
- •22. Lung defense mechanisms
- •Physical or anatomic factors
- •Antimicrobial peptides
- •Phagocytic and inflammatory cells
- •Adaptive immune responses
- •Failure of respiratory defense mechanisms
- •Augmentation of respiratory defense mechanisms
- •Suggested readings
- •23. Pneumonia
- •Etiology and pathogenesis
- •Pathology
- •Pathophysiology
- •Clinical features and initial diagnosis
- •Therapeutic approach: General principles and antibiotic susceptibility
- •Initial management strategies based on clinical setting of pneumonia
- •Suggested readings
- •24. Bacterial and viral organisms causing pneumonia
- •Bacteria
- •Viruses
- •Intrathoracic complications of pneumonia
- •Respiratory infections associated with bioterrorism
- •Suggested readings
- •25. Tuberculosis and nontuberculous mycobacteria
- •Etiology and pathogenesis
- •Definitions
- •Pathology
- •Pathophysiology
- •Clinical manifestations
- •Diagnostic approach
- •Principles of therapy
- •Nontuberculous mycobacteria
- •Suggested readings
- •26. Miscellaneous infections caused by fungi, including Pneumocystis
- •Fungal infections
- •Pneumocystis infection
- •Suggested readings
- •27. Pulmonary complications in the immunocompromised host
- •Acquired immunodeficiency syndrome
- •Pulmonary complications in non–HIV immunocompromised patients
- •Suggested readings
- •28. Classification and pathophysiologic aspects of respiratory failure
- •Definition of respiratory failure
- •Classification of acute respiratory failure
- •Presentation of gas exchange failure
- •Pathogenesis of gas exchange abnormalities
- •Clinical and therapeutic aspects of hypercapnic/hypoxemic respiratory failure
- •Suggested readings
- •29. Acute respiratory distress syndrome
- •Physiology of fluid movement in alveolar interstitium
- •Etiology
- •Pathogenesis
- •Pathology
- •Pathophysiology
- •Clinical features
- •Diagnostic approach
- •Treatment
- •Suggested readings
- •30. Management of respiratory failure
- •Goals and principles underlying supportive therapy
- •Mechanical ventilation
- •Selected aspects of therapy for chronic respiratory failure
- •Suggested readings
- •Index
an infectious pneumonia, although acute lung transplant rejection can present in a similar fashion. Heart failure (often secondary to cardiac toxicity from chemotherapeutic agents), pulmonary dissemination of the underlying malignancy, and hemorrhage into the pulmonary parenchyma are other causes of infiltrates that can closely mimic infectious etiologies. In many circumstances, an interstitial inflammatory process can be proved histologically, but no definite cause can be identified. These cases often are diagnosed as nonspecific interstitial pneumonitis, with the realization that neither the pathology nor the clinical history provides a specific etiologic diagnosis.
Suggested readings
Infectious pulmonary complications of HIV infection
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Fishman J.A. Pneumocystis jiroveci Seminars in Respiratory and Critical Care Medicine 2020;41: 141-157.
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Garland J.M, Levinson A. & Wing E. Care of critically ill patients with human immunodeficiency virus Annals of the American Thoracic Society 2020;17: 659-669.
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Uthman O.A, Okwundu C, Gbenga K, Volmink J, Dowdy D, Zumla A., et al. Optimal timing of antiretroviral therapy initiation for HIV-infected adults with newly diagnosed pulmonary tuberculosis: A systematic review and meta-analysis Annals of Internal Medicine 2015;163: 32-39.
Noninfectious complications of HIV infection
Basyal B, Jarrett H. & Barnett C.F. Pulmonary hypertension in HIV Canadian Journal of Cardiology 2019;35: 288-298.
Dittmer D.P. & Damania B. Kaposi sarcoma-associated herpesvirus: Immunobiology, oncogenesis, and therapy Journal of Clinical Investigation 2016;126: 3165-3175.
Hon S.M, Alpizar-Rivas R.M. & Farber H.W. Pulmonary arterial hypertension in patients
Данная книга находится в списке для перевода на русский язык сайта https://meduniver.com/
infected with the human immunodeficiency virus Cardiology Clinics 2022;40: 45-54. Kimani S.M, Painschab M.S, Horner M.J, Muchengeti M, Fedoriw Y, Shiels M.S., et al.
Epidemiology of haematological malignancies in people living with HIV Lancet HIV 2020;7: e641e651.
Panchabhai T.S, Farver C. & Highland K.B. Lymphocytic interstitial pneumonia Clinics in Chest Medicine 2016;37: 463-474.
Presti R.M, Flores S.C, Palmer B.E, Atkinson J.J, Lesko C.R, Lau B., et al. Mechanisms underlying HIV associated noninfectious lung disease Chest 2017;152: 1053-1060.
Sigel K, Pitts R. & Crothers K. Lung malignancies in HIV infection Seminars in Respiratory and Critical Care Medicine 2016;37: 267-276.
Yarchoan R. & Uldrick T.S. HIV-associated cancers and related diseases New England Journal of Medicine 2018;378: 1029-1041.
Pulmonary disease associated with non−HIV immunocompromise
Fung M. & Babik J.M. COVID-19 in immunocompromised hosts: What we know so far
Clinical Infectious Diseases 2021;72: 340-350.
Gupta S, Pattanaik D. & Krishnaswamy G. Common variable immune deficiency and associated complications Chest 2019;156: 579-593.
Joean O, Welte T. & Gottlieb J. Chest infections after lung transplantation Chest 2022;161: 937-948.
José R.J, Periselneris J.N. & Brown J.S. Opportunistic bacterial, viral and fungal infections of the lung Medicine (Abingdon) 2020;48: 366-372.
Lease E.D. & Budev M.M. Infectious complications in lung transplant recipients Thoracic Surgery Clinics 2022;32: 211-220.
McCort M, MacKenzie E, Pursell K. & Pitrak D. Bacterial infections in lung transplantation
Journal of Thoracic Disease 2021;13: 6654-6672.
Morelli T, Fujita K, Redelman-Sidi G. & Elkington P.T. Infections due to dysregulated immunity: an emerging complication of cancer chemotherapy Thorax 2022;77: 302-311.
Munting A. & Manuel O. Viral infections in lung transplantation Journal of Thoracic Disease 2021;13: 6673-6694.
Ramirez J.A, Musher D.M, Evans S.E, Dela Cruz C, Crothers K.A, Hage C.A., et al.
Treatment of community-acquired pneumonia in immunocompromised adults: A consensus statement regarding initial strategies Chest 2020;158: 1896-1911.
Salt E, Wiggins A.T, Rayens M.K, Huaman M.A, Mannino D, Schwieterman P., et al. Risk factors for targeted fungal and mycobacterial infections in patients taking tumor necrosis factor inhibitors Arthritis and Rheumatology 2016;68: 597-603.
Samanta P, Clancy C.J. & Nguyen M.H. Fungal infections in lung transplantation Journal of Thoracic Disease 2021;13: 6695-6707.
Young A.Y, Leiva Juarez M.M. & Evans S.E. Fungal pneumonia in patients with hematologic malignancy and hematopoietic stem cell transplantation Clinics in Chest Medicine 2017;38: 479-491.