- •Table of Contents
- •Copyright
- •Dedication
- •Introduction to the eighth edition
- •Online contents
- •List of Illustrations
- •List of Tables
- •1. Pulmonary anatomy and physiology: The basics
- •Anatomy
- •Physiology
- •Abnormalities in gas exchange
- •Suggested readings
- •2. Presentation of the patient with pulmonary disease
- •Dyspnea
- •Cough
- •Hemoptysis
- •Chest pain
- •Suggested readings
- •3. Evaluation of the patient with pulmonary disease
- •Evaluation on a macroscopic level
- •Evaluation on a microscopic level
- •Assessment on a functional level
- •Suggested readings
- •4. Anatomic and physiologic aspects of airways
- •Structure
- •Function
- •Suggested readings
- •5. Asthma
- •Etiology and pathogenesis
- •Pathology
- •Pathophysiology
- •Clinical features
- •Diagnostic approach
- •Treatment
- •Suggested readings
- •6. Chronic obstructive pulmonary disease
- •Etiology and pathogenesis
- •Pathology
- •Pathophysiology
- •Clinical features
- •Diagnostic approach and assessment
- •Treatment
- •Suggested readings
- •7. Miscellaneous airway diseases
- •Bronchiectasis
- •Cystic fibrosis
- •Upper airway disease
- •Suggested readings
- •8. Anatomic and physiologic aspects of the pulmonary parenchyma
- •Anatomy
- •Physiology
- •Suggested readings
- •9. Overview of diffuse parenchymal lung diseases
- •Pathology
- •Pathogenesis
- •Pathophysiology
- •Clinical features
- •Diagnostic approach
- •Suggested readings
- •10. Diffuse parenchymal lung diseases associated with known etiologic agents
- •Diseases caused by inhaled inorganic dusts
- •Hypersensitivity pneumonitis
- •Drug-induced parenchymal lung disease
- •Radiation-induced lung disease
- •Suggested readings
- •11. Diffuse parenchymal lung diseases of unknown etiology
- •Idiopathic pulmonary fibrosis
- •Other idiopathic interstitial pneumonias
- •Pulmonary parenchymal involvement complicating systemic rheumatic disease
- •Sarcoidosis
- •Miscellaneous disorders involving the pulmonary parenchyma
- •Suggested readings
- •12. Anatomic and physiologic aspects of the pulmonary vasculature
- •Anatomy
- •Physiology
- •Suggested readings
- •13. Pulmonary embolism
- •Etiology and pathogenesis
- •Pathology
- •Pathophysiology
- •Clinical features
- •Diagnostic evaluation
- •Treatment
- •Suggested readings
- •14. Pulmonary hypertension
- •Pathogenesis
- •Pathology
- •Pathophysiology
- •Clinical features
- •Diagnostic features
- •Specific disorders associated with pulmonary hypertension
- •Suggested readings
- •15. Pleural disease
- •Anatomy
- •Physiology
- •Pleural effusion
- •Pneumothorax
- •Malignant mesothelioma
- •Suggested readings
- •16. Mediastinal disease
- •Anatomic features
- •Mediastinal masses
- •Pneumomediastinum
- •Suggested readings
- •17. Anatomic and physiologic aspects of neural, muscular, and chest wall interactions with the lungs
- •Respiratory control
- •Respiratory muscles
- •Suggested readings
- •18. Disorders of ventilatory control
- •Primary neurologic disease
- •Cheyne-stokes breathing
- •Control abnormalities secondary to lung disease
- •Sleep apnea syndrome
- •Suggested readings
- •19. Disorders of the respiratory pump
- •Neuromuscular disease affecting the muscles of respiration
- •Diaphragmatic disease
- •Disorders affecting the chest wall
- •Suggested readings
- •20. Lung cancer: Etiologic and pathologic aspects
- •Etiology and pathogenesis
- •Pathology
- •Suggested readings
- •21. Lung cancer: Clinical aspects
- •Clinical features
- •Diagnostic approach
- •Principles of therapy
- •Bronchial carcinoid tumors
- •Solitary pulmonary nodule
- •Suggested readings
- •22. Lung defense mechanisms
- •Physical or anatomic factors
- •Antimicrobial peptides
- •Phagocytic and inflammatory cells
- •Adaptive immune responses
- •Failure of respiratory defense mechanisms
- •Augmentation of respiratory defense mechanisms
- •Suggested readings
- •23. Pneumonia
- •Etiology and pathogenesis
- •Pathology
- •Pathophysiology
- •Clinical features and initial diagnosis
- •Therapeutic approach: General principles and antibiotic susceptibility
- •Initial management strategies based on clinical setting of pneumonia
- •Suggested readings
- •24. Bacterial and viral organisms causing pneumonia
- •Bacteria
- •Viruses
- •Intrathoracic complications of pneumonia
- •Respiratory infections associated with bioterrorism
- •Suggested readings
- •25. Tuberculosis and nontuberculous mycobacteria
- •Etiology and pathogenesis
- •Definitions
- •Pathology
- •Pathophysiology
- •Clinical manifestations
- •Diagnostic approach
- •Principles of therapy
- •Nontuberculous mycobacteria
- •Suggested readings
- •26. Miscellaneous infections caused by fungi, including Pneumocystis
- •Fungal infections
- •Pneumocystis infection
- •Suggested readings
- •27. Pulmonary complications in the immunocompromised host
- •Acquired immunodeficiency syndrome
- •Pulmonary complications in non–HIV immunocompromised patients
- •Suggested readings
- •28. Classification and pathophysiologic aspects of respiratory failure
- •Definition of respiratory failure
- •Classification of acute respiratory failure
- •Presentation of gas exchange failure
- •Pathogenesis of gas exchange abnormalities
- •Clinical and therapeutic aspects of hypercapnic/hypoxemic respiratory failure
- •Suggested readings
- •29. Acute respiratory distress syndrome
- •Physiology of fluid movement in alveolar interstitium
- •Etiology
- •Pathogenesis
- •Pathology
- •Pathophysiology
- •Clinical features
- •Diagnostic approach
- •Treatment
- •Suggested readings
- •30. Management of respiratory failure
- •Goals and principles underlying supportive therapy
- •Mechanical ventilation
- •Selected aspects of therapy for chronic respiratory failure
- •Suggested readings
- •Index
although patients may require additional treatments with whole-lung lavage. The long-term effects of exogenous GM-CSF in this disease are unknown.
Suggested readings
Idiopathic pulmonary fibrosis
Albert R.K. & Schwartz D.A. Revealing the secrets of idiopathic pulmonary fibrosis New England Journal of Medicine 2019;380: 94-96.
Collard H.R, Ryerson C.J, Corte T.J, Jenkins G, Kondoh Y, Lederer D.J., et al. Acute exacerbation of idiopathic pulmonary fibrosis. An International Working Group Report
American Journal of Respiratory and Critical Care Medicine 2016;194: 265-275. Flaherty K.R, Wells A.U, Cottin V, Devaraj A, Walsh S.L.F, Inoue Y., et al. Nintedanib in progressive fibrosing interstitial lung diseases New England Journal of Medicine
2019;381: 1718-1727.
Katzen J. & Beers M.F. Contributions of alveolar epithelial cell quality control to pulmonary fibrosis Journal of Clinical Investigation 2020;130: 5088-5099.
King T.E.Jr, Bradford W.Z, Castro-Bernardini S, Fagan E.A, Glaspole I, Glassberg M.K., et al. A phase 3 trial of pirfenidone in patients with idiopathic pulmonary fibrosis New England Journal of Medicine 2014;370: 2083-2092.
Lederer D.J. & Martinez F.J. Idiopathic pulmonary fibrosis New England Journal of Medicine 2018;378: 1811-1823.
Rackow A.R, Nagel D.J, McCarthy C, Judge J, Lacy S, Freeberg M.A.T., et al. The selffulfilling prophecy of pulmonary fibrosis: A selective inspection of pathological signaling loops European Respiratory Journal 2020;56: 2000075.
Raghu G, Remy-Jardin M, Myers J.L, Richeldi L, Ryerson C.J, Lederer D.J., et al. Diagnosis of idiopathic pulmonary fibrosis. An official ATS/ERS/JRS/ALAT clinical practice guideline American Journal of Respiratory and Critical Care Medicine 2018;198: e44e68.
Thomson C.C, Duggal A, Bice T, Lederer D.J, Wilson K.C. & Raghu G. 2018 Clinical practice guideline summary for clinicians: Diagnosis of idiopathic pulmonary fibrosis
Annals of the American Thoracic Society 2019;16: 285-290.
Whitsett J.A, Kalin T.V, Xu Y. & Kalinichenko V.V. Building and regenerating the lung cell by cell Physiological Reviews 2019;99: 513-554.
Wijsenbeek M. & Cottin V. Spectrum of fibrotic lung diseases New England Journal of Medicine 2020;383: 958-968.
Other idiopathic interstitial pneumonias
American Thoracic Society & European Respiratory Society. American Thoracic Society/European Respiratory Society international multidisciplinary consensus classification of the idiopathic interstitial pneumonias American Journal of Respiratory and Critical Care Medicine 2002;165: 277-304.
King T.E,Jr. & Lee J.S. Cryptogenic organizing pneumonia New England Journal of Medicine 2022;386: 1058-1069.
Kumar A, Cherian S.V, Vassallo R, Yi E.S. & Ryu J.H. Current concepts in pathogenesis, diagnosis, and management of smoking-related interstitial lung diseases Chest 2018;154:
394-408.
Raghu G. & Meyer K.C. Cryptogenic organising pneumonia: Current understanding of an enigmatic lung disease European Respiratory Review 2021;30: 210094.
Travis W.D, Costabel U, Hansell D.M, King T.E.Jr, Lynch D.A, Nicholson A.G., et al. An official American Thoracic Society/European Respiratory Society statement: Update of the international multidisciplinary classification of the idiopathic interstitial pneumonias American Journal of Respiratory and Critical Care Medicine 2013;188: 733748.
Pulmonary parenchymal involvement complicating connective tissue disease
Doyle T.J. & Dellaripa P.F. Lung manifestations in the rheumatic diseases Chest 2017;152: 1283-1295.
Fischer A. & du Bois R. Interstitial lung disease in connective tissue disorders Lancet 2012;380: 689-698.
Hannah J.R. & D’Cruz D.P. Pulmonary complications of systemic lupus erythematosus
Seminars in Respiratory and Critical Care Medicine 2019;40: 227-234.
Kadura S. & Raghu G. Rheumatoid arthritis-interstitial lung disease: Manifestations and current concepts in pathogenesis and management European Respiratory Review 2021;30: 210011.
Khanna D, Tashkin D.P, Denton C.P, Renzoni E.A, Desai S.R. & Varga J. Etiology, risk factors, and biomarkers in systemic sclerosis with interstitial lung disease American Journal of Respiratory and Critical Care Medicine 2020;201: 650-660.
Lee A.S, Scofield R.H, Hammitt K.M, Gupta N, Thomas D.E, Moua T., et al. Consensus guidelines for evaluation and management of pulmonary disease in Sjögren’s Chest 2021;159: 683-698.
Morisset J, Johnson C, Rich E, Collard H.R. & Lee J.S. Management of myositis-related interstitial lung disease Chest 2016;150: 1118-1128.
Perelas A, Silver R.M, Arrossi A.V. & Highland K.B. Systemic sclerosis-associated interstitial lung disease Lancet Respiratory Medicine 2020;8: 304-320.
Tsuchiya Y, Fischer A, Solomon J.J. & Lynch D.A. Connective tissue disease-related thoracic disease Clinics in Chest Medicine 2015;36: 283-297.
Sarcoidosis
Baughman R.P, Valeyre D, Korsten P, Mathioudakis A.G, Wuyts W.A, Wells A., et al. ERS clinical practice guidelines on treatment of sarcoidosis European Respiratory Journal 2021;58: 2004079.
Belperio J.A, Shaikh F, Abtin F.G, Fishbein M.C, Weigt S.S, Saggar R., et al. Diagnosis and treatment of pulmonary sarcoidosis. A review JAMA 2022;327: 856-867.
Celada L.J, Hawkins C. & Drake W.P. The etiologic role of infectious antigens in sarcoidosis pathogenesis Clinics in Chest Medicine 2015;36: 561-568.
Crouser E.D, Maier L.A, Wilson K.C, Bonham C.A, Morgenthau A.S, Patterson K.C., et al.
Diagnosis and detection of sarcoidosis. An official American Thoracic Society clinical practice guideline American Journal of Respiratory and Critical Care Medicine 2020;201: e26e51.
Drent M, Crouser E.D. & Grunewald J. Challenges of sarcoidosis and its management New
Данная книга находится в списке для перевода на русский язык сайта https://meduniver.com/
England Journal of Medicine 2021;385: 1018-1032.
Fingerlin T.E, Hamzeh N. & Maier L.A. Genetics of sarcoidosis Clinics in Chest Medicine 2015;36: 569-584.
Patterson K.C. & Chen E.S. The pathogenesis of pulmonary sarcoidosis and implications for treatment Chest 2018;153: 1432-1442.
Rahaghi F.F, Baughman R.P, Saketkoo L.A, Sweiss N.J, Barney J.B, Birring S.S., et al. Delphi consensus recommendations for a treatment algorithm in pulmonary sarcoidosis
European Respiratory Review 2020;29: 190146.
Singha A, Liao S.Y, Herman D.D, Crouser E.D, Maier L.A, Baughman R.P., et al. Summary for clinicians: Clinical practice guideline for the diagnosis and detection of sarcoidosis
Annals of the American Thoracic Society 2020;17: 1510-1515.
Thillai M, Atkins C.P, Crawshaw A, Hart S.P, Ho L.P, Kouranos V., et al. BTS clinical statement on pulmonary sarcoidosis Thorax 2021;76: 4-20.
Zissel G. & Müller-Quernheim J. Cellular players in the immunopathogenesis of sarcoidosis
Clinics in Chest Medicine 2015;36: 549-560.
Miscellaneous disorders involving the pulmonary parenchyma
Allen C.E, Merad M. & McClain K.L. Langerhans-cell histiocytosis New England Journal of Medicine 2018;379: 856-868.
Bernheim A. & McLoud T. A review of clinical and imaging findings in eosinophilic lung diseases AJR 2017;208: 1002-1010.
Cottin V. Eosinophilic lung diseases Clinics in Chest Medicine 2016;37: 535-556. Feemster L.C, Lyons P.G, Chatterjee R.S, Kidambi P, McCormack F.X, Moss J., et al.
Summary for clinicians: Lymphangioleiomyomatosis diagnosis and management clinical practice guideline Annals of the American Thoracic Society 2017;14: 1073-1075.
Gupta N, Finlay G.A, Kotloff R.M, Strange C, Wilson K.C, Young L.R., et al.
Lymphangioleiomyomatosis diagnosis and management: High-resolution chest computed tomography, transbronchial lung biopsy, and pleural disease management. An official American Thoracic Society/Japanese Respiratory Society clinical practice guideline
American Journal of Respiratory and Critical Care Medicine 2017;196: 1337-1348. Kadura S. & Raghu G. Antineutrophil cytoplasmic antibody-associated interstitial lung
disease: A review European Respiratory Review 2021;30: 210123.
Kumar A, Abdelmalak B, Inoue Y. & Culver D.A. Pulmonary alveolar proteinosis in adults: Pathophysiology and clinical approach Lancet Respiratory Medicine 2018;6: 554-565.
McCarthy C, Carey B.C. & Trapnell B.C. Autoimmune pulmonary alveolar proteinosis
American Journal of Respiratory and Critical Care Medicine 2022;205: 1016-1035. McCarthy C, Gupta N, Johnson S.R, Yu J.J. & McCormack F.X. Lymphangioleiomyomatosis:
Pathogenesis, clinical features, diagnosis, and management Lancet Respiratory Medicine 2021;9: 1313-1327.
McCormack F.X, Gupta N, Finlay G.R, Young L.R, Taveira-DaSilva A.M, Glasgow C.G., et al. Official American Thoracic Society/Japanese Respiratory Society clinical practice guidelines: Lymphangioleiomyomatosis diagnosis and management American Journal of Respiratory and Critical Care Medicine 2016;194: 748-761.
Radzikowska E. Update on pulmonary Langerhans cell histiocytosis Frontiers in Medicine 2021;7: 582581.
Shaw B, Borchers M, Zander D. & Gupta N. Pulmonary Langerhans cell histiocytosis
Seminars in Respiratory and Critical Care Medicine 2020;41: 269-279.
Shin J.I, Geetha D, Szpirt W.M, Windpessl M. & Kronbichler A. Anti-glomerular basement membrane disease (Goodpasture disease): From pathogenesis to plasma exchange to IdeS Therapeutic Apheresis and Dialysis 2022;26: 24-31.
Trapnell B.C, Inoue Y, Bonella F, Morgan C, Jouneau S, Bendstrup E., et al. Inhaled molgramostim therapy in autoimmune pulmonary alveolar proteinosis New England Journal of Medicine 2020;383: 1635-1644.
Walsh M, Merkel P.A, Peh C.A, Szpirt W.M, Puéchal X, Fujimoto S., et al. Plasma exchange and glucocorticoids in severe ANCA-associated vasculitis New England Journal of Medicine 2020;382: 622-631.
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