TABLE 20.1
Lung Cancer: Comparative Features
Cell Type |
Frequency |
Locationb |
Radiographic |
Spread |
|
(%)a |
|
Appearancec |
|
Non-Small-Cell Lung Cancer (NSCLC) |
|
|
||
|
|
|
|
|
Squamous cell |
20–25 |
Proximal, |
1. Central mass |
Contiguous |
|
|
endobronchial |
intrathoracic |
|
|
|
|
2. Obstructive |
spread; |
|
|
|
atelectasis |
nodal |
|
|
|
3. Postobstructive |
metastasis |
|
|
|
pneumonia |
|
|
|
|
|
|
Adenocarcinoma (and |
50 |
Peripheral |
Solitary peripheral |
Contiguous |
other adenocarcinoma |
|
|
nodule or mass |
intrathoracic |
spectrum lesions) |
|
|
|
spread; |
|
|
|
|
nodal and |
|
|
|
|
distant |
|
|
|
|
metastasis |
|
|
|
|
|
Large cell |
2–5 |
Variable |
Variable; often large |
Contiguous |
|
|
|
peripheral mass |
intrathoracic |
|
|
|
|
spread; |
|
|
|
|
nodal and |
|
|
|
|
distant |
|
|
|
|
metastasis |
|
|
|
|
|
Small-Cell Lung Cancer (SCLC) |
|
|
|
|
|
|
|
|
|
Small cell (including oat |
10–15 |
Proximal, |
1. Central mass |
Hilar, |
cell) |
|
endobronchial |
mediastinal |
|
|
|
(submucosal) |
2. Hilar, |
nodes; |
|
|
|
mediastinal |
distant |
|
|
|
adenopathy |
metastasis |
|
|
|
|
|
aApproximate percent of all lung cancers.
bMost common location; for all cell types, variable locations are seen. cCommon presentations on chest radiograph.
Suggested readings
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