- •Table of Contents
- •Copyright
- •Dedication
- •Introduction to the eighth edition
- •Online contents
- •List of Illustrations
- •List of Tables
- •1. Pulmonary anatomy and physiology: The basics
- •Anatomy
- •Physiology
- •Abnormalities in gas exchange
- •Suggested readings
- •2. Presentation of the patient with pulmonary disease
- •Dyspnea
- •Cough
- •Hemoptysis
- •Chest pain
- •Suggested readings
- •3. Evaluation of the patient with pulmonary disease
- •Evaluation on a macroscopic level
- •Evaluation on a microscopic level
- •Assessment on a functional level
- •Suggested readings
- •4. Anatomic and physiologic aspects of airways
- •Structure
- •Function
- •Suggested readings
- •5. Asthma
- •Etiology and pathogenesis
- •Pathology
- •Pathophysiology
- •Clinical features
- •Diagnostic approach
- •Treatment
- •Suggested readings
- •6. Chronic obstructive pulmonary disease
- •Etiology and pathogenesis
- •Pathology
- •Pathophysiology
- •Clinical features
- •Diagnostic approach and assessment
- •Treatment
- •Suggested readings
- •7. Miscellaneous airway diseases
- •Bronchiectasis
- •Cystic fibrosis
- •Upper airway disease
- •Suggested readings
- •8. Anatomic and physiologic aspects of the pulmonary parenchyma
- •Anatomy
- •Physiology
- •Suggested readings
- •9. Overview of diffuse parenchymal lung diseases
- •Pathology
- •Pathogenesis
- •Pathophysiology
- •Clinical features
- •Diagnostic approach
- •Suggested readings
- •10. Diffuse parenchymal lung diseases associated with known etiologic agents
- •Diseases caused by inhaled inorganic dusts
- •Hypersensitivity pneumonitis
- •Drug-induced parenchymal lung disease
- •Radiation-induced lung disease
- •Suggested readings
- •11. Diffuse parenchymal lung diseases of unknown etiology
- •Idiopathic pulmonary fibrosis
- •Other idiopathic interstitial pneumonias
- •Pulmonary parenchymal involvement complicating systemic rheumatic disease
- •Sarcoidosis
- •Miscellaneous disorders involving the pulmonary parenchyma
- •Suggested readings
- •12. Anatomic and physiologic aspects of the pulmonary vasculature
- •Anatomy
- •Physiology
- •Suggested readings
- •13. Pulmonary embolism
- •Etiology and pathogenesis
- •Pathology
- •Pathophysiology
- •Clinical features
- •Diagnostic evaluation
- •Treatment
- •Suggested readings
- •14. Pulmonary hypertension
- •Pathogenesis
- •Pathology
- •Pathophysiology
- •Clinical features
- •Diagnostic features
- •Specific disorders associated with pulmonary hypertension
- •Suggested readings
- •15. Pleural disease
- •Anatomy
- •Physiology
- •Pleural effusion
- •Pneumothorax
- •Malignant mesothelioma
- •Suggested readings
- •16. Mediastinal disease
- •Anatomic features
- •Mediastinal masses
- •Pneumomediastinum
- •Suggested readings
- •17. Anatomic and physiologic aspects of neural, muscular, and chest wall interactions with the lungs
- •Respiratory control
- •Respiratory muscles
- •Suggested readings
- •18. Disorders of ventilatory control
- •Primary neurologic disease
- •Cheyne-stokes breathing
- •Control abnormalities secondary to lung disease
- •Sleep apnea syndrome
- •Suggested readings
- •19. Disorders of the respiratory pump
- •Neuromuscular disease affecting the muscles of respiration
- •Diaphragmatic disease
- •Disorders affecting the chest wall
- •Suggested readings
- •20. Lung cancer: Etiologic and pathologic aspects
- •Etiology and pathogenesis
- •Pathology
- •Suggested readings
- •21. Lung cancer: Clinical aspects
- •Clinical features
- •Diagnostic approach
- •Principles of therapy
- •Bronchial carcinoid tumors
- •Solitary pulmonary nodule
- •Suggested readings
- •22. Lung defense mechanisms
- •Physical or anatomic factors
- •Antimicrobial peptides
- •Phagocytic and inflammatory cells
- •Adaptive immune responses
- •Failure of respiratory defense mechanisms
- •Augmentation of respiratory defense mechanisms
- •Suggested readings
- •23. Pneumonia
- •Etiology and pathogenesis
- •Pathology
- •Pathophysiology
- •Clinical features and initial diagnosis
- •Therapeutic approach: General principles and antibiotic susceptibility
- •Initial management strategies based on clinical setting of pneumonia
- •Suggested readings
- •24. Bacterial and viral organisms causing pneumonia
- •Bacteria
- •Viruses
- •Intrathoracic complications of pneumonia
- •Respiratory infections associated with bioterrorism
- •Suggested readings
- •25. Tuberculosis and nontuberculous mycobacteria
- •Etiology and pathogenesis
- •Definitions
- •Pathology
- •Pathophysiology
- •Clinical manifestations
- •Diagnostic approach
- •Principles of therapy
- •Nontuberculous mycobacteria
- •Suggested readings
- •26. Miscellaneous infections caused by fungi, including Pneumocystis
- •Fungal infections
- •Pneumocystis infection
- •Suggested readings
- •27. Pulmonary complications in the immunocompromised host
- •Acquired immunodeficiency syndrome
- •Pulmonary complications in non–HIV immunocompromised patients
- •Suggested readings
- •28. Classification and pathophysiologic aspects of respiratory failure
- •Definition of respiratory failure
- •Classification of acute respiratory failure
- •Presentation of gas exchange failure
- •Pathogenesis of gas exchange abnormalities
- •Clinical and therapeutic aspects of hypercapnic/hypoxemic respiratory failure
- •Suggested readings
- •29. Acute respiratory distress syndrome
- •Physiology of fluid movement in alveolar interstitium
- •Etiology
- •Pathogenesis
- •Pathology
- •Pathophysiology
- •Clinical features
- •Diagnostic approach
- •Treatment
- •Suggested readings
- •30. Management of respiratory failure
- •Goals and principles underlying supportive therapy
- •Mechanical ventilation
- •Selected aspects of therapy for chronic respiratory failure
- •Suggested readings
- •Index
modes of therapy must be instituted. Nocturnal positive-pressure ventilation is generally helpful in improving daytime sleepiness, particularly if the patient has concomitant obstructive sleep apnea syndrome (see Chapter 18). In some patients with impaired respiratory drive, respiratory stimulants, especially progesterone (a centrally acting respiratory stimulant), have been used with limited success.
Suggested readings
Neuromuscular disease affecting the muscles of respiration
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Ambrosino N, Carpenè N. & Gherardi M. Chronic respiratory care for neuromuscular diseases in adults European Respiratory Journal 2009;34: 444-451.
Benditt J.O. Respiratory care of patients with neuromuscular disease Respiratory Care 2019;64: 679-688.
Bittner E.A, Martyn J.A, George E, Frontera W.R. & Eikermann M. Measurement of muscle strength in the intensive care unit Critical Care Medicine 2009;37: S321-S330.
Derenne J.P, Macklem P.T. & Roussos C. The respiratory muscles: Mechanics, control, and pathophysiology American Review of Respiratory Disease 1978;118: 581-601.
Gilhus N.E. Myasthenia gravis New England Journal of Medicine 2016;375: 2570-2581. Hocker S. Primary acute neuromuscular respiratory failure Neurologic Clinics 2017;35:
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Gonzalez H, Olsson T. & Borg K. Management of postpolio syndrome Lancet Neurology 2010;9: 634-642.
Neumann B, Angstwurm K, Mergenthaler P, Kohler S, Schönenberger S, Bösel J., et al.
Myasthenic crisis demanding mechanical ventilation: A multicenter analysis of 250 cases Neurology 2020;94: e299-e313.
Niedermeyer S, Murn M. & Choi P.J. Respiratory failure in amyotrophic lateral sclerosis
Chest 2019;155: 401-408.
Rabinstein A.A. Noninvasive ventilation for neuromuscular respiratory failure: When to use and when to avoid Current Opinion in Critical Care 2016;22: 94-99.
Shahrizaila N, Lehmann H.C. & Kuwabara S. Guillain-Barré syndrome Lancet 2021;97: 1214-1228.
van Doorn J.L.M, Pennati F, Hansen H.H.G, van Engelen B.G.M, Aliverti A. & Doorduin J.
Respiratory muscle imaging by ultrasound and MRI in neuromuscular disorders
European Respiratory Journal 2021;58: 2100137.
Diaphragmatic disease
Aguirre V.J, Sinha P, Zimmet A, Lee G.A, Kwa L. & Rosenfeldt F. Phrenic nerve injury during cardiac surgery: Mechanisms, management and prevention Heart, Lung & Circulation 2013;22: 895-902.
Mador M.J. Respiratory muscle fatigue and breathing patterns Chest 1991;100: 1430-1435.
McCool F.D. & Tzelepis G.E. Dysfunction of the diaphragm New England Journal of
Данная книга находится в списке для перевода на русский язык сайта https://meduniver.com/
Medicine 2012;366: 932-942.
Podgaetz E, Garza-Castillon R,Jr. & Andrade R.S. Best approach and benefit of plication for paralyzed diaphragm Thoracic Surgery Clinics 2016;26: 333-346.
Rafiq A, Ijaz M, Tariq H, Vakde T. & Duncalf R. Failing phrenics: An obscure cause of exertional dyspnea: Case report and literature review Medicine (Baltimore) 2016;95: e4263.
Ricoy J, Rodríguez-Núñez N, Álvarez-Dobaño J.M, Toubes M.E, Riveiro V. & Valdés L. Diaphragmatic dysfunction Pulmonology 2019;25: 223-235.
Roussos C. & Macklem P.T. The respiratory muscles New England Journal of Medicine 1982;307: 786-797.
Steimer D, DeBarros M, Marshall M.B. & Jaklitsch M. Thoracoscopic radial diaphragm plication Annals of Thoracic Surgery 2022;114: e227-e230.
Supinski G.S, Morris P.E, Dhar S. & Callahan L.A. Diaphragm dysfunction in critical illness Chest 2018;153: 1040-1051.
Diseases affecting the chest wall
Baffi C.W, Wood L, Winnica D, Strollo P.J,Jr, Gladwin M.T, Que L.G., et al. Metabolic syndrome and the lung Chest 2016;149: 1525-1534.
Baydur A. & Milic-Emili J. Respiratory mechanics in kyphoscoliosis Monaldi Archives for Chest Disease 1993;48: 69-79.
Böing S. & Randerath W.J. Chronic hypoventilation syndromes and sleep-related hypoventilation Journal of Thoracic Disease 2015;7: 1273-1285.
Davis G, Patel J.A. & Gagne D.J. Pulmonary considerations in obesity and the bariatric surgical patient Medical Clinics of North America 2007;91: 433-442.
Fischer A.J, Kaese S. & Lebiedz P. Management of obese patients with respiratory failure - A practical approach to a health care issue of increasing significance Respiratory Medicine 2016;117: 174-178.
Fuschillo S, De Felice A, Martucci M, Gaudiosi C, Pisano V, Vitale D., et al. Pulmonary rehabilitation improves exercise capacity in subjects with kyphoscoliosis and severe respiratory impairment Respiratory Care 2015;60: 96-101.
Kafer E.R. Respiratory and cardiovascular functions in scoliosis Bulletin europeen de physiopathologie respiratoire 1977;13: 299-321.
Mafort T.T, Rufino R, Costa C.H. & Lopes A.J. Obesity: Systemic and pulmonary complications, biochemical abnormalities, and impairment of lung function
Multidisciplinary Respiratory Medicine 2016;11: 28.
Masa J.F, Pépin J.L, Borel J.C, Mokhlesi B, Murphy P.B. & Sánchez-Quiroga M.Á. Obesity hypoventilation syndrome European Respiratory Review 2019;28: 180097.
McMaster M.J, Glasby M.A, Singh H. & Cunningham S. Lung function in congenital kyphosis and kyphoscoliosis Journal of Spinal Disorders and Techniques 2007;20: 203208.
Mokhlesi B, Masa J.F, Brozek J.L, Gurubhagavatula I, Murphy P.B, Piper A.J., et al.
Evaluation and management of obesity hypoventilation syndrome. An official American Thoracic Society clinical practice guideline American Journal of Respiratory and Critical Care Medicine 2019;200: e6-e24.
Pépin J.L, Timsit J.F, Tamisier R, Borel J.C, Lévy P. & Jaber S. Prevention and care of respiratory failure in obese patients Lancet Respiratory Medicine 2016;4: 407-418.
Peters U, Suratt B.T, Bates J.H.T. & Dixon A.E. Beyond BMI: Obesity and lung disease Chest 2018;153: 702-709.
Pierce A.M. & Brown L.K. Obesity hypoventilation syndrome: Current theories of pathogenesis Current Opinion in Pulmonary Medicine 2015;21: 557-562.
Piesiak P, Brzecka A, Kosacka M. & Jankowska R. Efficacy of noninvasive volume targeted ventilation in patients with chronic respiratory failure due to kyphoscoliosis Advances in Experimental Medicine and Biology 2015;838: 53-58.
Piper A. Obesity hypoventilation syndrome: Weighing in on therapy options Chest 2016;149: 856-868.
Sutton F.D,Jr, Zwillich C.W, Creagh C.E, Pierson D.J. & Weil J.V. Progesterone for outpatient treatment of Pickwickian syndrome Annals of Internal Medicine 1975;83: 476479.
Данная книга находится в списке для перевода на русский язык сайта https://meduniver.com/