Книги по МРТ КТ на английском языке / Functional Neuroimaging in Child Psychiatry Ernst 1 ed 2000
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Functional neuroimaging in child psychiatry
This unprecedented book reviews the recent rapid development of functional neuroimaging techniques and their implications for child psychiatry. It is unique in its focus on children and in integrating brain mapping with genetics and behavioral testing ± an interface that is likely to become fundamental to functional neuroimaging. Presenting new imaging techniques in language accessible to the nonspecialist, this invaluable reference will help clinicians and investigators to:
·understand through imaging the mechanisms of childhood psychiatric disorders
·decide which technique is most appropriate for their purposes, with respect to technology, experimental design, data analysis, and ethical considerations
·appreciate the role of molecular genetics and neuropsychology in planning brain imaging studies.
Coverage includes description of new brain imaging strategies, recent advances and future applications of neuroimaging for child psychiatry, and the application to children of imaging techniques used in adults. As background, an overview is given of normal brain and cognitive development. Linking the latest
Wndings from neuroimaging to neurophysiologic models, this book is an essential resource for researchers and clinicians concerned with neurodevelopmental disorders.
Monique Ernst is Associate Director of the Brain Imaging Center at the US National Institute on Drug Abuse.
Judith M. Rumsey is Chief of the US Developmental Neuroscience of Schizophrenia, Mood and other Brain Disorders Program, Clinical Neuroscience Branch, National Institute of Mental Health.
Functional neuroimaging in child psychiatry
Edited by
Monique Ernst
Brain Imaging Center,
National Institute on Drug Abuse, Baltimore, MD, USA
and
Judith M. Rumsey
Clinical Neuroscience Branch,
National Institute of Mental Health, Rockville, MD, USA
With a Foreword by
Joseph T. Coyle
Chairman, Department of Psychiatry, Harvard Medical School, Boston, MA, USA
p u b l i s h e d b y t h e p r e s s s y n d i c at e o f t h e u n i v e r s i t y o f c a m b r i d g e
The Pitt Building, Trumpington Street, Cambridge, United Kingdom
c a m b r i d g e u n i v e r s i t y p r e s s
The Edinburgh Building, Cambridge CB2 2RU, UK 40 West 20th Street, New York, NY 10011-4211, USA 10 Stamford Road, Oakleigh, VIC 3166, Australia Ruiz de Alarcón 13, 28014 Madrid, Spain
Dock House, The Waterfront, Cape Town 8001, South Africa
http://www.cambridge.org
© Cambridge University Press 2000
This book is in copyright. Subject to statutory exception
and to the provisions of relevant collective licensing agreements, no reproduction of any part may take place without
the written permission of Cambridge University Press.
First published 2000
Reprinted 2001
Printed in the United Kingdom at the University Press, Cambridge
Typeface Utopia 8.5/12 pt. System QuarkXPress® [s e ]
A catalogue record for this book is available from the British Library
Library of Congress Cataloguing in Publication data
Functional neuroimaging in child psychiatry / edited by Monique Ernst and Judith M. Rumsey
p. ; cm.
Includes index.
ISBN 0 521 65044 5 (hb)
1. Pediatric neuropsychiatry. 2. Brain±Imaging. 3. Developmental neurophysiology. I. Ernst, Monique, 1953± . II. Rumsey, Judith M.
[DNLM: 1. Mental Disorders ± diagnosis ± Child. 2. Brain Diseases ± diagnosis ± Child. 3. Diagnostic Imaging ± Child. WS 350 F979 2000]
RJ486.5.F865 2000 |
|
618.929890754±dc 21 |
99±04455 |
ISBN 0 521 65044 5 hardback
Every effort has been made in preparing this book to provide accurate and up-to-date information which is in accord with accepted standards and practice at the time of publication. Nevertheless, the authors, editors and publisher can make no warranties that the information contained herein is totally free from error, not least because clinical standards are constantly changing through research and regulation. The authors, editors and publisher therefore disclaim all liability for direct or consequential damages resulting from the use of material contained in this book. Readers are strongly advised to pay careful attention to information provided by the manufacturer of any drugs or equipment that they plan to use.
The views stated herein do not necessarily represent the of®cial views of the National Institute on Drug Abuse, the National Institute of Mental Health, the National Institutes of Health nor the Department of Health and Human Services, nor any other agency of the United States government.
Contents
List of contributors |
page vii |
Preface |
xi |
Foreword |
xiii |
Joseph T. Coyle |
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Part 1 Techniques of functional imaging
1 |
Functional brain imaging with PET and SPECT |
3 |
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Peter Herscovitch and Monique Ernst |
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2 |
Modeling of receptor images in PET and SPECT |
27 |
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Evan D. Morris, Raymond F. Muzic Jr, |
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Bradley C. Christian, Christopher J. Endres and |
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Ronald E. Fisher |
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3 |
Functional magnetic resonance imaging |
45 |
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Guinevere F. Eden and Thomas A. ZeYro |
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4 |
MRS in childhood psychiatric disorders |
59 |
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Deborah A. Yurgelun-Todd and Perry F. Renshaw |
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5 |
Magnetoencephalography |
77 |
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Donald C. Rojas, Peter D. Teale and Martin L. Reite |
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Part 2 Ethical foundations
6 Ethical issues in neuroimaging research with |
99 |
children |
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L. Eugene Arnold, Alan J. Zametkin, Lauren |
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Caravella and Nicole Korbly |
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Part 3 Normal development
7 Brain development and evolution |
113 |
Manuel F. Casanova, Daniel Buxhoeveden and
Gurkirpal S. Sohal
v
vi Contents
8 |
Cognitive development from a |
137 |
17 Eating disorders |
298 |
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neuropsychologic perspective |
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Uttom Chowdhury, Isky Gordon and Bryan Lask |
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Daisy M. Pascualvaca and Gloria Morote |
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9 |
Cognitive and behavioral probes of |
155 |
Part 5 Future directions |
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developmental landmarks for use in functional |
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neuroimaging |
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18 Techniques of molecular genetics |
315 |
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B. J. Casey, Kathleen M. Thomas, Tomihisa F. Welsh, |
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David J. Vandenbergh |
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Rona Livnat and Clayton H. Eccard |
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19 Issues in the genetic study of complex |
328 |
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neurobehavioral conditions |
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Part 4 Psychiatric disorders |
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David L. Pauls |
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20 The duplicity of plasticity: a conceptual |
335 |
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10 |
Autism |
171 |
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approach to the study of early lesions and |
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Diane C. Chugani |
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developmental disorders |
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11 |
Functional imaging in childhood-onset |
189 |
Ralph-Axel Müller and Eric Courchesne |
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schizophrenia |
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21 Utility of CANTAB in functional |
366 |
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Leslie K. Jacobsen and Alessandro Bertolino |
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neuroimaging |
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12 |
Pediatric mood disorders and neuroimaging |
205 |
Andy C. H. Lee, Adrian M. Owen, |
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Robert A. Kowatch, Pablo A. Davanzo and |
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Robert D. Rogers, Barbara J. Sahakian and |
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Graham J. Emslie |
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Trevor W. Robbins |
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13 |
Neuroimaging of childhood-onset anxiety |
224 |
22 Neurodevelopmental assessment of cognitive |
379 |
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disorders |
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function using CANTAB: validation and |
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David R. Rosenberg, Lori Anne D. Paulson, |
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future goals |
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Frank P. MacMaster and Gregory J. Moore |
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Monica Luciana and Charles A. Nelson |
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14 |
Tourette's syndrome: what are we really imaging? 242 |
23 Functional neuroimaging in child psychiatry: |
398 |
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Bradley S. Peterson and Prakash Thomas |
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future directions |
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15 |
Dyslexia: conceptual issues and psychiatric |
266 |
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Monique Ernst and Judith M. Rumsey |
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comorbidity |
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Glossary |
408 |
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Frank B. Wood and D. Lynn Flowers |
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Index |
418 |
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16 |
Attention-de®cit hyperactivity disorder: |
278 |
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neuroimaging and behavioral/cognitive probes |
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Colour plates between pp. 82 and pp. 83 and between |
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Julie B. Schweitzer, Carl Anderson and |
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pp. 242 and pp. 243 |
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Monique Ernst |
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Contributors
Carl Anderson
Department of Psychiatry, Harvard Medical School,
Boston, MA, USA
L. Eugene Arnold
Professor Emeritus of Psychiatry, Ohio State University,
Columbus, OH 43210, USA
Alessandro Bertolino
Clinical Brain Disorders Branch, National Institute of Mental Health, NIH, Bethesda, MD 20892, USA
Daniel Buxhoeveden
Medical College of Georgia, Augusta, GA 30910, USA
Lauren Caravella
National Institute of Mental Health, NIH, Bethesda, MD
10892, USA
Manuel F. Casanova
Medical College of Georgia, Augusta, GA 30910, USA
B. J. Casey
Sackler Institute for Developmental Psychobiology, Weill Medical College of Cornell University, New York, NY 10021, USA
Uttom Chowdhury
Department of Psychological Medicine, Great Ormond Street Hospital for Children, London WCIN 3JH, UK
Bradley C. Christian
Wright State University and Kettering Memorial Hospital,
Kettering, OH 45429, USA
Diane C. Chugani
Wayne State University and Children's Hospital of Michigan PET Center, Detroit, MI 48201, USA
Eric Courchesne
Department of Neurosciences and the Children's Hospital Research Center for the Neuroscience of Autism, University of California, San Diego, CA 92037, USA
vii
viiiList of contributors
Pablo A. Davanzo
University of California, Los Angeles, CA, USA
Clayton H. Eccard
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
Guinevere F. Eden
Institute for Cognitive and Computational Sciences, Georgetown University Medical Center, Washington, DC 20007-2197, USA
Graham J. Emslie
Department of Psychiatry, South Western Medical Center at Dallas, Dallas, TX 75235-9070, USA
Christopher J. Endres
Johns Hopkins University, Baltimore, MD, USA
Monique Ernst
Brain Imaging Center, National Institute on Drug Abuse, Baltimore, MD 21224, USA
Ronald E. Fisher
Baylor College of Medicine (Houston) and Veterans AVairs Hospital, Houston, TX, USA
D. Lynn Flowers
Department of Neurology, Bowman Gray School of Medicine, Winston Salem, NC 27157-1043, USA
Isky Gordon
Great Ormond Street Hospital for Children, London, WCIN 3JH, UK
Peter Herscovitch
NIH Clinical Center, National Institutes of Health,
Bethesda, MD 20892-1180, USA
Leslie K. Jacobsen
Department of Psychiatry, Yale School of Medicine, West
Haven, CT 06516, USA
Nicole Korbly
National Institute of Mental Health, NIH, Bethesda, MD
10892, USA
Robert A. Kowatch
Department of Psychiatry, South Western Medical Center at Dallas, Dallas, TX 5235-9070, USA
Bryan Lask
Great Ormond Street Hospital for Children, London WCIN 3JH, UK
Andy C. H. Lee
Department of Experimental Psychology, University of
Cambridge, Cambridge CB2 3EB, UK
Rona Livnat
Department of Psychiatry, University of Pittsburgh,
Pittsburgh, PA 15213, USA
Monica Luciana
Department of Psychology and Institute of Child
Development, University of Minnesota, Minneapolis, MN
55455, USA
Frank P. MacMaster
Wayne State University School of Medicine, Department
of Psychiatry and Behavioral Neurosciences, Detroit, MI
48201, USA
Gregory J. Moore
Wayne State University School of Medicine, Department
of Psychiatry and Behavioral Neurosciences, Detroit, MI
48201, USA
Gloria Morote
Psychiatric Associates of Alexandria, Alexandria, VA
22314, USA
Evan D. Morris
Sensor Systems, Sterling, VA, USA
Ralph-Axel Müller
Department of Cognitive Science and the Children's Hospital Research Center for the Neuroscience of Autism, University of California, San Diego, CA 92037, USA
Raymond F. Muzic Jr
Case Western Reserve University and University Hospital of Cleveland, OH 44106, USA
Charles A. Nelson
Department of Pediatrics and Institute of Child
Development, University of Minnesota, Minneapolis, MN
55455, USA
Adrian M. Owen
Wolfson Brain Imaging Centre, Cambridge, UK
Daisy M. Pascualvaca
Section on Clinical and Experimental Neuropsychology, Laboratory of Brain Cognition, National Institute of Mental Health, Bethesda, MD 20892, USA
David L. Pauls
Child Study Center, Yale University School of Medicine, New Haven, CT 06150, USA
Lori Anne D. Paulson
Wayne State University School of Medicine, Department
of Psychiatry and Behavioral Neurosciences, Detroit, MI
48201, USA
Bradley S. Peterson
Yale Child Study Center, New Haven, CT 06520, USA
Martin L. Reite
University of Colorado Health Sciences and Denver Veterans AVairs Medical Center, Denver, CO 80262, USA
Perry F. Renshaw
Brain Imaging Center, Belmont, MA 02178, USA
Trevor W. Robbins
Department of Experimental Psychology, University of Cambridge and the MRC Cognitive and Brain Sciences Unit, Cambridge CB2 3EB, UK
Robert D. Rogers
Department of Experimental Psychology, University of
Cambridge, Cambridge CB2 3EB, UK
Donald C. Rojas
University of Colorado Health Sciences Center, Denver,
CO 80262, USA
David R. Rosenberg
Wayne State University School of Medicine, Department
of Psychiatry and Behavioral Neurosciences, Detroit, MI
48201, USA
Judith M. Rumsey
Clinical Neuroscience Branch, National Institute of
Mental Health, Rockville, MD 20857, USA
Barbara J. Sahakian
Department of Psychiatry, University of Cambridge,
Cambridge, UK
Julie B. Schweitzer
Maryland Psychiatric Research Center, University of
Maryland, Baltimore, MD 21228, USA
List of contributors |
ix |
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Gurkirpal S. Sohal
Medical College of Georgia, Augusta, GA 30910, USA
Peter D. Teale
University of Colorado Health Sciences, Denver, CO
80262, USA
Kathleen M. Thomas
Department of Psychiatry, University of Pittsburgh,
Pittsburgh, PA 15213, USA
Prakash Thomas
Yale University, New Haven, CT 06520, USA
David J.Vandenbergh
Center for Developmental and Health Genetics and Department of Biobehavioral Health, The Pennsylvania State University, Philadelphia, PA 16802, USA
Tomihisa F. Welsh
Department of Psychiatry, University of Pittsburgh,
Pittsburgh, PA 15213, USA
Frank B. Wood
Section of Neuropsychology, Wake Forest University
Baptist Medical Center, Winston Salem, NC 27157-1043,
USA
Deborah A.Yurgelun-Todd
Brain Imaging Center, McLean Hospital and Harvard
Medical School, Boston, MA, USA
Alan J. Zametkin
Division of Intramural Research, Child Psychiatry Branch,
National Institute of Mental Health, NIH, Bethesda, MD
20892, USA
Thomas A. ZeYro
Sensor Systems, Sterling, VA 20164, USA