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WoUnd HEaling and PrinciPlEs of Plastic sUrgEry

(or dangling). The microvascular free transfer

7.

Rumalla VK, Borah GL. Cytokines, growth factors, and

flap, also referred to as a free flap, has both the

8.

plastic surgery. Plast Reconstr Surg. 2001;108:719-733

vascular supply and skin interrupted. The vas-

Nwometh BC, Olutoye OO, Diegelmann RF, et al. The

 

basic biology of wound healing. J Surg Pathol. 1997;2:

cular supply is then reestablished at the recipi-

 

 

143-162

ent site.

 

9.

Gupta S,Lawrence WT.Wound healing: normal and abnor-

Again, there is confusion in terminology. In

 

mal mechanisms and closure techniques.In: O’Leary JP,ed.

genitourinary reconstructive surgical proce-

 

The Physiologic Basis for Surgery. 4th ed. Philadelphia, PA:

dures, we tend to use the term island flap. As

10.

Lippincott Williams & Wilkins; 2008

already mentioned, a true island flap is elevated

Barrientos S, Stojadinovic O, Golinko MS, et al. Growth

 

factors and cytokines in wound healing. Wound Repair

on dangling vessels. The usual case, however, is

 

 

Regen. 2008;16(5):585-601

that a skin island or paddle is elevated either on

 

11.

Ethridge R, Leong M, Phillips LG. Wound healing. In:

the muscle, as in the gracilis musculocutaneous

 

Townsend CM, ed. Sabiston’s Textbook of Surgery. 18th

flap, or on the fascia, as in local genital skin flaps

 

ed. Philadelphia, PA: Saunders; 2007

(Fig. 19.11). The term island flap is not synony-

12.

Kavitha O, Thampan RV. Factors influencing collagen

mous with the terms skin island and skin paddle.

13.

biosynthesis. J Cell Biochem. 2008;104(4):1150-1160

Interest continues in the use of tissue-cultured,

Thackham JA, McElwain DL, Long RJ. The use of hyper-

 

baric oxygen therapy to treat chronic wounds: a review.

or engineered, grafts. The likelihood of being

 

 

Wound Repair Regen. 2008;16(3):321-330

able to successfully use cultured media is right

 

14.

Fine NA, Mustoe TA. Wound healing. In Greenfield’s

around the corner.

 

Surgery: Scientific Principles and Practice, 4th ed.

 

 

Lippincott Williams and Wilkins, 2006

 

15.

Jordan GH, McCraw JB. Tissue transfer techniques for

References

 

genitourinary reconstructive surgery, Part II – Basic flap

 

definitions and techniques/graft techniques.AUA Update

 

 

Series; Lesson 10, Vol VII. 1988

1. Meyer FA, Fromjmovic MM, Vi MM. Characteristics of

16.

Witte MB, Barbul A. General principles of wound heal-

the major platelet membrane site used in binding colla-

 

ing. Surg Clin North Am. 1997;77:509-527

gen. Thromb Res. 1979;15:755-767

17.

Jordan GH, Schlossberg SM. Using tissue transfer for

2. Jurk K, Kehrel BE. Platelets: physiology and biochemis-

 

urethral reconstruction. Contemp Urol. 1993;5(12):

try. Semin Thromb Hemost. 2005;31(4):381-392

 

13-23

3. Martin P, Leibovich SJ. Inflammatory cells during wound

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Jordan GH, Schlossberg SM. Surgery of the Penis and

repair: the good, the bad and the ugly. Trends Cell Biol.

 

Urethra. In: Wein AJ, ed. Campbell-Walsh Urology. 9th ed.

2005;15(11):599-607

 

Philadelphia, PA: Saunders Elsevier; 2007

4. Leibovich SJ, Ross R. The role of the macrophage in

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Jordan GH, Schlossberg SM, McCraw JB. Tissue transfer

wound repair: a study with hydrocortisone and anti-

 

techniques for genitourinary reconstructive surgery,

macrophage serum. Am J Pathol. 1975;78:71-100

 

Part I – Principles, definitions, basic techniques and

5. Clark RAF. Would Repair: overview and general consid-

 

graft techniques. AUA Update Series. Lesson 9, Vol VII.

erations (Chatper1). In The molecular and Cellular

 

1998

Biology of Wound Repair, 2nd ed., Springer, 1996

20.

Jordan GH, Rourke K. The use of flaps in urethral recon-

6. Digelmann RF, Cohen IK, Kaplan AM. The role of mac-

 

structive surgery. In Reconstructive Urethral Surgery

rophages in wound repair: a review. Plast Reconstr Surg.

 

edited by Schreiter and JOrdan; Springer: 2006;16:

1981;68:107-113

 

130-136