ГЛАВА 8
11.Brandi G., Paiardini M., Cervasi В., Fiorucci C, Filippone P., De Mar co C, Zaffaroni N.. Magnani M. A new indole-3-carbinol tetrameric derivati ve inhibits cyclin-dependent kinase 6 expression, and induces G1 cell cycle arrest in both estrogen-dependent and estrogen-independent breast cancer cell lines. Cancer Res, 2003, Jul 15, 63(14), 4028-36.
12.Brignall M.S. Prevention and treatment of cancer with indole-3-carbi- nol. Altern Med Rev, 2001, Dec, 6(6), 580-9.
13.Calle E.E, Kaaks R. Overweight, obesity and cancer, epidemiological evidence and proposed mechanisms. Nat Rev Cancer, 2004, Aug, 4(8), 579-91.
14.Cao Y., Cao R. Angiogenesis inhibited by drinking tea. Nature, 1999, 398,381.
15.Cardoso F., Di Leo A., Larsimont D., Gancberg D., Rouas G., Dolci S., Ferreira F., Paesmans M., Piccart M. Evaluation of HER2, p53, bcl-2, topoisomerase ll-alpha, heat shock proteins 27 and 70 in primary breast can cer and metastatic ipsilateral axillary lymph nodes. Ann Oncol, 2001, May, 12(5), 615-20.
16.Chakrabarti O., Veeraraghavalu K., Tergaonkar V., Liu Y., Androphy E.J., Stanley M.A., Krishna S. Human papillomavirus type 16 E6 amino acid 83 variants enhance E6-mediated МАРК signaling and differentially regulate tumorigenesis by notch signaling and oncogenic Ras. J Virol, 2004, Jun, 78(11), 5934-45.
17.Chantre P., Lairon D. Recent findings of green tea extract AR25 (Exolise) and its activity for the treatment of obesity. Phytomedicine, 2002, Jan, 9(1), 3-8.
18.Chatterji LL, Riby J.E., Taniguchi Т., Bjeldanes E.L., Bjeldanes LF, Firestone GL lndole-3-carbinol stimulates transcription of the interferon gamma receptor 1 gene and augments interferon responsiveness in human breast cancer cells. Carcinogenesis, 2004, Feb 26.
19.Chen P., Yang C.C., Chen Y.J., Wang P.H. Tamoxifen-induced en dometrial cancer. Eur J Gynaecol Oncol, 2003, 24(2), 135-137.
20.Chinni S.R., Sarkar F.H. Akt inactivation is a key event in indole-3- carbinol-induced apoptosis in PC-3 cells. Clin Cancer Res, 2002, Apr, 8(4), 1228-36.
21.Chung J.H., Han J.H., Hwang E.J., Seo J.Y., Cho K.H., Kim K.H., Youn J.I., Eun H.C. Dual mechanisms of green tea extract (EGCG)-induced
Обоснованные направления терапии и профилактики...
cell survival in human epidermal keratinocytes. FASEB J, 2003, Oct, 17(13), 1913-5.
22.Ciocca D.R., Luque E.H. Immunological evidence for the identity between the hsp27 estrogen-regulated heat shock protein and the p29 estro gen receptor-associated protein in breast and endometrial cancer. Breast Cancer Res Treat, 1991, 20(1), 33-42.
23.Coll D.A., Rosen C.A., Auborn K„ Potsic W.P., Bradlow H i . Treat ment of recurrent respiratory papillomatosis with indole-3-carbinol. Am J Oto laryngol, 1997, Jul-Aug, 18(4), 283-5.
24.Couillard S., Gutman M., Labrie C, Belanger A., Candas В., Labrie F. Comparison of the effects of the antiestrogens EM-800 and tamoxifen on the growth of human breast ZR-75-1 cancer xenografts in nude mice. Can cer Res, 1998, Jan 1, 58(1), 60-4.
25.Cover СМ., Hsieh S.J., Cram E.J., Hong C, Riby J.E., Bjeldanes L.F., Firestone G.L. lndole-3-carbinol and tamoxifen cooperate to arrest the cell cy cle of MCF-7 human breast cancer cells. Cancer Res, 1999, Mar 15, 59(6), 1244-51.
26.Cram E.J., Liu B.D., Bjeldanes L.F., Firestone G.L. lndole-3-carbinol inhibits CDK6 expression in human MCF-7 breast cancer cells by disrupting Sp1 transcription factor interactions with a composite element in the CDK6 gene promoter. J Biol Chem, 2001, Jun, 22, 276(25), 22332-40.
27.Crew K.D., Neugut A.I. Epidemiology of upper gastrointestinal malig nancies. Semin Oncol, 2004, Aug, 31(4), 450-64.
28.Curtis R.E., Freedman D.M., Sherman M.E., Fraumeni J.F. Jr. Risk of malignant mixed mullerian tumors after tamoxifen therapy for breast can cer. J Natl Cancer Inst, 2004, 96,1, 70-74.
29.Dalton T.P., Shertzer H.G., Puga A. Regulation of gene expression by reactive oxygen. Annu Rev Pharmacol Toxicol, 1999, 39, 67-101.
30.Detmar M. Evidence for vascular endothelial growth factor (VEGF) as a modifier gene in psoriasis. J Invest Dermatol, 2004, Jan, 122(1), XIV-XV.
31.Firestone G.L., Bjeldanes L.F. lndole-3-carbinol and З-З'-diindolyl- methane antiproliferative signaling pathways control cell-cycle gene transcrip tion in human breast cancer cells by regulating promoter-Sp1 transcription factor interactions. J Nutr, 2003, Jul, 133(7 Suppl), 2448S-2455S.
Обоснованные направления терапии и профилактики...
42.Hegarty V.M., May H.M., Khaw K.T. Tea drinking and bone mineral density in older women. Am J Clin Nutr, 2000, 71,1003-1007.
43.Hong J., Smith T.J., Но СТ., August D.A., Yang C.S. Effects of pu rified green and black tea polyphenols on cyclooxygenaseand lipoxyge- nase-dependent metabolism of arachidonic acid in human colon mucosa and colon tumor tissues. Biochem Pharmacol, 2001, 62,1175-1183.
44.Houghton J.P, loffe O.B., Silverberg S.G., McGrady B, McCluggage W.G. Metastatic breast lobular carcinoma involving tamoxifen-associated endometrial polyps: report of two cases and review of tamoxifen-associated polypoid uterine lesions. Mod Pathol, 2003, Apr, 16(4), 395-8.
45.Howells L.M., Gallacher-Horley В., Houghton C.E., Manson M.M., Hudson E.A. lndole-3-carbinol inhibits protein kinase B/Akt and induces apoptosis in the human breast tumor cell line MDA MB468 but not in the nontumorigenic HBL100 line. Mol Cancer Ther, 2002, Nov, 1(13), 1161-72.
46.Huang S., New L, Pan Z., Han J., Nemerow G.R. Urokinase plasmi nogen activator/urokinase-specific surface receptor expression and matrix invasion by breast cancer cells requires constitutive p38alpha mitogen-acti- vated protein kinase activity. J Biol Chem, 2000, 275,12266-12272.
47.Jankun J., Keck R.W., Skrzypczak-Jankun E., Swiercz R. Inhibitors of urokinase reduce size of prostate cancer xenografts in severe combined immunodeficient mice. Cancer Res, 1997a, 57, 559-563.
48.Jankun J., Selman S.H., Swiercz R., Skrzypczak-Jankun E. Why drinking green tea could prevent cancer. Nature, 1997b, 387, 561.
49.Jeong W.S., Kim I.W., Hu R., Kong A.N. Modulatory properties of va rious natural chemopreventive agents on the activation of NF-kappaB signa ling pathway. Pharm Res, 2004, Apr, 21(4), 661-70.
50.Jung Y.D., Ellis LM. Inhibition of tumour invasion and angiogenesis by epigallocatechin gallate (EGCG), a major component of green tea. Int J Exp Pathol, 2001, Dec, 82(6), 309-16.
51.Jung Y.D., Kim M.S., Shin B.A., Chay K.O., Ahn B.W., Liu W., Bucana CD., Gallick G.E., Ellis LM. EGCG, a major component of green tea, inhi bits tumour growth by inhibiting VEGF induction in human colon carcinoma cells. Br J Cancer, 2001, Mar, 23, 84(6), 844-50.
ГЛАВА 8
32.Friedrich К., Wieder Т., Von Haefen С, Radetzki S., Janicke R., Schulze-Osthoff K., Dorken В., Daniel P.T. Overexpression of caspase-3 restores sensitivity for drug-induced apoptosis in breast cancer cell lines with acquired drug resistance. Oncogene, 2001, May, 17, 20(22), 2749-60.
33.Furberg A.S., Veierod M.B., Wilsgaard Т., Bernstein L, Thune I. Se rum high-density lipoprotein cholesterol, metabolic profile, and breast cancer risk. J Natl Cancer Inst, 2004, Aug, 4, 96(15), 1152-60.
34.Garbisa S., Sartor L, Biggin S, Salvato В., Benelli R., Albini A. Tu mor gelatinases and invasion inhibited by the green tea flavanol epigalloca- techin-3-gallate. Cancer, 2001, 91, 822-832.
35.Garrido C, Schmitt E., Cande C, Vahsen N., Parcellier A., Kroemer G. HSP27 and HSP70: potentially oncogenic apoptosis inhibitors. Cell Cycle, 2003, Nov-Dec, 2(6), 579-84.
36.Gohji K., Nakajima M., Boyd D, Dinney СР., Bucana CD., Kitazana S., Kamidono S., Fidler I.J. Orgap-site dependence for the production of urokinase-type plasminogen activator and metastasis by human renal cell carcinoma cells. Am J Pathol, 1997, Dec, 151(6), 1655-61.
37.Golijanin D., Tan J.Y, Kazior A., Cohen E.G., Russo P., Dalbagni G., Auborn K.J., Subbaramaiah K., Dannenberg A.J. Cyclooxygenase-2 and microsomal prostaglandin E synthase-1 are overexpressed in squamous cell carcinoma of the penis. Clin Cancer Res, 2004, Feb, 1,10(3), 1024-31.
38.Goodin M.G., Rosengren R.J. Epigallocatechin gallate modulates CYP450 isoforms in the female Swiss-Webster mouse.Toxicol Sci, 2003, Dec, 76(2), 262-70.
39.Gottardis M.M, Jordan V.C Development of tamoxifen-stimulated growth of MCF-7 tumors in athymic mice after long-term antiestrogen admi nistration. Cancer Res, 1988, 48, 5183-5187.
40.Hamada S., Ooshima Т., Fijiwara Т., Minami Т., Kimura S. Develop ment of preventive measures based on the aetiology of dental caries-a revi ew. Microb Ecol Health Dis, 1996, 9, 349-357.
41.Hashiya N., Jo N., Aoki M., Matsumoto K., Nakamura Т., Sato Y., Ogata N., Ogihara Т., Kaneda Y., Morishita R. In vivo evidence of angiogenesis induced by transcription factor Ets-1, Ets-1 is located upstream of angiogenesis cascade. Circulation, 2004, Jun, 22,109(24), 3035-41.
Обоснованные направления терапии и профилактики...
62.Lin J., Zhang S.M., Cook N.R., Rexrode K.M., Lee I.M., Buring J.E. Body mass index and risk of colorectal cancer in women (United States). Cancer Causes Control, 2004, Aug, 15(6), 581-9.
63.Lord R.S., Bongiovanni В., Bralley J.A. Estrogen metabolism and the diet-cancer connection, rationale for assessing the ratio of urinary hydroxylated estrogen metabolites. Altern Med Rev, 2002 Apr, 7(2), 112-29.
64.Maeda-Yamamoto M., Kawahara H., Tahara N., Tsuju K., Hara Y., Isemura M. Effects of tea polyphenols on the invasion and matrix metalloproteinases activities of human fibrosarcoma HT1080 cells. J Agric Food Chem, 1999,47,2350-2354.
65.Makimura M., Hirasawa M., Kobayashi K., Indo J., Sakanaka S., Taguchi Т., Otake S. Inhibitory effect of tea catechins on collagenase activity. J Periodontal, 1993, Jul, 64(7), 630-6.
66.Mandel S., Weinreb O., Amit Т., Youdim M.B. Cell signaling pathwa ys in the neuroprotective actions of the green tea polyphenol (-)-epigalloca- techin-3-gallate, implications for neurodegenerative diseases. J Neurochem, 2004, Mar, 88(6), 1555-69.
67.Martinez-Arribas F., Nunez-Villar M.J., Lucas A.R., Sanchez J., Tejerina A., Schneider J. Immunofluorometric study of Bcl-2 and Bax expression in clinical fresh tumor samples from breast cancer patients. Anticancer Res, 2003, Jan-Feb, 23(1 B), 565-8.
68.Mittal A., Piyathilake C, Hara Y., Katiyar S.K. Exceptionally high pro tection of photocarcinogenesis by topical application of (-)-epigallocatechin- 3-gallate in hydrophilic cream in SKH-1 hairless mouse model, relationship to inhibition of UVB-induced global DNA hypomethylation. Neoplasia, 2003, 5, 6, 555-65.
69.Mutoh M., Takahashi M., Fukuda K., Matsushima-Hibiya Y., Mutoh H., Sugimura Т., Wakabayashi K. Suppression of cyclooxygenase-2 promo ter-dependent transcriptional activity in colon cancer cells by chemopreventive agents with a resorcin-type structure. Carcinogenesis, 2000, 21, 959-963.
70.Nair P., Nair K.M., Jayaprakash P.G., Pillai M.R. Decreased pro grammed cell death in the uterine cervix associated with high risk human pa pillomavirus infection. Pathol Oncol Res, 1999, 5, 2, 95-103.
71.Nakagawa Т., Yokozawa Т., Sano M., Takeuchi S., Kim M., Minamoto S. Activity of (-)-Epigallocatechin 3-O-Gallate against Oxidative Stress in
ГЛАВА 8
52.Katiyar S.K., Bergamo B.M., Vyalil P.K., Elmets C.A. Green tea po lyphenols, DNA photodamage and photoimmunology. J Photochem PhotobiolB, 2001, Dec, 31, 65(2-3), 109-14.
53.Katiyar S.K., Mukhtar H. Green tea polyphenol (-)-epigallocatechin- 3-gallate treatment to mouse skin prevents UVB-induced infiltration of leuko cytes, depletion of antigen-presenting cells, and oxidative stress. J Leukoc Biol, 2001, May, 69(5), 719-26.
54.Katiyar S.K. Skin photoprotection by green tea, antioxidant and im munomodulatory effects. Curr Drug Targets Immune Endocr Metabol Disord, 2003, Sep, 3(3), 234-42.
55.Kim J., Hwang J.S., Cho Y.K., Han Y., Jeon Y.J., Yang K.H. Protec tive effects of (-)-epigallocatechin-3-gallate on UVAand UVB-induced skin damage. Skin Pharmacol Appl Skin Physiol, 2001, Jan-Feb, 14(1), 11-9.
56. Kim M.H., Jung M A , Hwang Y.S., Jeong M., Kim S.M., Ahn S.J., Shin B.A., Ahn B.W., Jung YD. Regulation of urokinase plasminogen activa tor by epigallocatechin-3-gallate in human fibrosarcoma cells. Eur J Pharma col, 2004, Mar 8, 487(1-3), 1-6.
57.Lee I.J., Han F., Baek J., Hisatsune A., Kim K.C. Inhibition of MUC1 expression by indole-3-carbinol. Int J Cancer, 2004, May 10,109(6), 810-6.
58.Legha S.S. Tamoxifen in the treatment of breast cancer. Ann Intern Med, 1988,109,219-228.
59.Li H., Lindenmeyer F., Grenet C, Opolon P., Menashi S., Soria C, Yeh P., Perricaudet M., Lu H. AdTIMP-2 inhibits tumor growth, angiogenesis, and metastasis, and prolongs survival in mice. Hum Gene Ther, 2001, Mar 20,12(5), 515-26.
60.Liang Y.C., Huang Y., Tsai S., Lin-Shiau S., Chen C, Lin J. Suppres sion of inducible cyclooxygenase and inducible nitric oxide synthase by apigenin and related flavonoids in mouse macrophages. Carcinogenesis, 1999a, 20, 1945-1952.
61.Liang Y.C., Lin-Shiau S.Y., Chen C.F., Lin J.K. Inhibition of cyclin-de- pendent kinases 2 and 4 activities as well as induction of Cdk inhibitors p21 and p27 during growth arrest of human breast carcinoma cells by epigallocatechin- 3-gallate. J Cell Biochem, 1999b, 75,1-12.
О б о с н о в а н н ые направления т е р а п и и и профилактики...
tamoxifen associated endometrial carcinomas. Anticancer Res, 1998, NovDec, 18(6B), 4661-5.
81.Riethdorf L, Riethdorf S., Petersen S., Bauer M., Herbst H., Janicke F., Loning T. Urokinase gene expression indicates early invasive growth in squamous cell lesions of the uterine cervix. J Pathol, 1999, Oct, 189(2), 245-50.
82.Sakanaka S., Okada Y. Inhibitory effects of green tea polyphenols on the production of a virulence factor of the periodontal-disease-causing anae robic bacterium Porphyromonas gingivalis. J Agric Food Chem, 2004, 52(6), 1688-92.
83.Sakata R., Ueno Т., Nakamura Т., Sakamoto M., Torimura Т., Sata M. Green tea polyphenol epigallocatechin-3-gallate inhibits platelet-derived growth factor-induced proliferation of human hepatic stellate cell line LI90. J Hepatol, 2004, Jan, 40(1), 52-9.
84.Sarkar F.H., Rahman K.M., Li Y. Bax translocation to mitochondria is an important event in inducing apoptotic cell death by indole-3-carbinol (I3C) treatment of breast cancer cells. J Nutr, 2003,133, 7, 2434-2439.
85.Sayama K., Lin S., Zheng G., Oguni I. Effects of green tea on growth, food utilization and lipid metabolism in mice. In Vivo, 2000, Jul-Aug, 14(4), 481-4.
86.Shaheen R.M., Davis D.W., Liu W, Zebrowski B.K., Wilson M.R., Bucana CD., McConkey D.J., McMahon G., Ellis LM. Antiangiogenic thera py targeting the tyrosine kinase receptor for vascular endothelial growth fac tor receptor inhibits the growth of colon cancer liver metastasis and induces tumor and endothelial cell apoptosis. Cancer Res, 1999, Nov 1, 59(21), 5412-6.
87.Singh A.K, Seth P., Anthony P., Husain M.M., Madhavan S., Mukhtar H, Maheshwari R.K. Green tea constituent epigallocatechin-3-gal- late inhibits angiogenic differentiation of human endothelial cells. Arch Biochem Biophys, 2002, May 1, 401(1), 29-37.
88.Stanley M. Chapter 17, Genital human papillomavirus infections-cur rent and prospective therapies. J Natl Cancer Inst Monogr, 2003, 31,117-24.
89.Taioli E., Garte S.J., Trachman J., Garbers S., Sepkovic D.W., Os borne M.P., Mehl S., Bradlow H I . Ethnic differences in estrogen metabolism in healthy women. J Natl Cancer Inst, 1996, May 1, 88(9), 617.
Г Л А ВА 8
Rats with Adenine-lnduced Renal Failure. J Agric Food Chem, 2004, Apr 7, 52(7), 2103-2107.
72.Osborne C.K., Coronado-Heinsohn E.B., Hilsenbeck S.G., McCue B.L., Wakeling A.E., McClelland R.A., Manning D.L, Nicholson R.I. Compa rison of the effects of a pure steroidal antiestrogen with those of tamoxifen in a model of human breast cancer. J Natl Cancer Inst, 1995, May 17, 87(10), 746-50.
73.Park J.W, Choi Y.J., Suh S.I., Kwon Т.К. Involvement of ERK and protein tyrosine phosphatase signaling pathways in EGCG-induced cycloox- ygenase-2 expression in Raw 264.7 cell. Biochem Biophys Res Commun, 2001,286,721-725.
74.Parkin D.R., Malejka-Giganti D. Differences in the hepatic P450-de- pendent metabolism of estrogen and tamoxifen in response to treatment of rats with 3,3'-diindolylmethane and its parent compound indole-3-carbinol. Cancer Detect Prev, 2004, 28(1), 72-9.
75.Peitsaro P., Ruutu M., Syrjanen S., Johansson B. Divergent expres sion changes of telomerase and E6/E7 mRNA, following integration of hu man papillomavirus type 33 in cultured epithelial cells. Scand J Infect Dis, 2004, 36(4), 302-4.
76.Plug-DeMaggio A.W., Sundsvold Т., Wurscher M.A, Koop J.I., Klingelhutz A.J., McDougall J.K. Telomere erosion and chromosomal instability in cells expressing the HPV oncogene 16E6. Oncogene, 2004, Apr 29, 23(20), 3561-71.
77.Porter W., Wang F., Duan R., Qin C, Castro-Rivera E., Safe S. Transcriptional activation of heat shock protein 27 gene expression by 17bestradiol and modulation by antiestrogens and aryl hydrocarbon receptor ago nists, estrogenic activity of IC1164,384. J Mol Endocrinol, 2000, 26, 31-42.
78.Rahman K.M., Aranha O., Sarkar F.H. lndole-3-carbinol (I3C) indu ces apoptosis in tumorigenic but not in nontumorigenic breast epithelial cells. Nutr Cancer, 2003, 45, 1,101-112.
79.Ramirez-Mares M.V., de Mejia E.G. Comparative study of the antioxi dant effect of ardisin and epigallocatechin gallate in rat hepatocytes exposed to benomyl and 1-nitropyrene. Food Chem Toxicol, 2003, Nov, 41(11), 1527-35.
80.Ramondetta L.M., Palazzo J.P., Dunton C.J., Kovatich A.J., Carlson J.A. A comparative analysis of Ki-67, p53, and p21 WAF1CIP1 expression in
Обоснованные направления терапии и профилактики...
100.Wilkinson M.G., Millar J.B.A. Control of the eukaryotic cell cycle by MAP kinase signaling pathways. FASEB J, 2000,14, 21472157.
101.Yamaguchi M., Jie Z. Effect of polyphenols on calcium content and alkaline phosphatase activity in rat femoral tissues in vitro. Biol Pharm Bull, 2001, Dec, 24(12), 1437-9.
102.Yang C.S., Landau J.M. Effects of tea consumption on nutrition and health. J Nutr, 2000, Oct, 130(10), 2409-12.
103.Yokoyama M., Noguchi M., Nakao Y., Pater A., Iwasaka T. The tea polyphenol, (-)-epigallocatechin gallate effects on growth, apoptosis, and telomerase activity in cervical cell lines. Gynecol Oncol, 2004, Jan, 92(1), 197-204.
104.Young H.S., Summers A.M., Bhushan M., Brenchley P.E., Griffiths C.E. Single-nucleotide polymorphisms of vascular endothelial growth factor in psoriasis of early onset. J Invest Dermatol, 2004, Jan, 122(1), 209-15.
105.Zheng G., Sayama K., Okubo Т., Juneja L.R., Oguni I. Anti-obesity effects of three major components of green tea, catechins, caffeine and theanine, in mice. In Vivo, 2004, Jan-Feb, 18(1), 55-62.
106.Zheng Y, Song H.J, Kim C.H., Kim H.S, Kim E.G., Sachinidis A, Ahn H.Y. Inhibitory effect of epigallocatechin 3-O-gallate on vascular smooth muscle cell hypertrophy induced by angiotensin II. J Cardiovasc Pharmacol, 2004, Feb 43(2), 200-8.
ГЛАВА 8
90.Talvensaari A., Apaja-Sarkkinen M., Hoyhtya M., Westerlund A., Puistola U., Turpeenniemi Т. Matrix metalloproteinase 2 immunoreactive pro tein appears early in cervical epithelial dedifferentiation. Gynecol Oncol, 1999, Mar, 72(3), 306-11.
91.Tang F.Y., Nguyen N., Meydani M. Green tea catechins inhibit VEGF-induced angiogenesis in vitro through suppression of VE-cadherin phosphorylation and inactivation of Akt molecule. Int J Cancer, 2003, Oct 10, 106(6), 871-8.
92.Tarani A., Negri E., LaVecchia C. Food and nutrient intake and risk of cataract. Ann Epidemiol, 1996, 6, 41-46.
93.Toussaint-Smith E., Donner D.B., Roman A. Expression of human papillomavirus type 16 E6 and E7 oncoproteins in primary foreskin keratinocytes is sufficient to alter the expression of angiogenic factors. Oncogene, 2004, Apr 15, 23(17), 2988-95.
94.Turner M.A., Palefsky J.M. Urokinase plasminogen activator expres sion by primary and HPV 16-transformed keratinocytes. Clin Exp Metastasis, 1995, Jul, 13(4), 260-8.
95.Vayalil P.K., Elmets С A., Katiyar S.K. Treatment of green tea polyphe nols in hydrophilic cream prevents UVB-induced oxidation of lipids and pro teins, depletion of antioxidant enzymes and phosphorylation of МАРК proteins in SKH-1 hairless mouse skin. Carcinogenesis, 2003, May, 24(5), 927-36.
96.Vayalil P.K., Katiyar S.K. Treatment of epigallocatechin-3-gallate inhibits matrix metalloproteinases-2 and -9 via inhibition of activation of mito- gen-activated protein kinases, c-jun and NF-kappaB in human prostate car cinoma DU-145 cells. Prostate, 2004, Apr 1, 59(1), 33-42.
97.Vitaglione P., Fogliano V. Use of antioxidants to minimize the human health risk associated to mutagenic/carcinogenic heterocyclic amines in food. J Chromatogr В Analyt Technol Biomed Life Sci, 2004, Mar 25,802(1), 189-99.
98.Wei Y.H., Lee H.C. Oxidative stress, mitochondrial DNA mutation, and impairment of antioxidant enzymes in aging. Exp Biol Med (Maywood), 2002, Oct, 227(9), 671-82.
99.Wheeler D.S., Catravas J.D., Odoms K., Denenberg A., Malhotra V., Wong H.R. Epigallocatechin-3-gallate, a green tea-derived polyphenol, inhi bits IL-1 beta-dependent proinflammatory signal transduction in cultured res piratory epithelial cells. J Nutr, 2004, May, 134(5), 1039-44.