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Appendix

Sedatives and Pain Medications

Non-intubated patients

Intubated patients

Non-opioid analgesics

Non-opioid analgesics

Acetaminophen (500–1,000 mg po q6h)

Acetaminophen (500–1,000 mg po q6h)

NSAID (Ibuprofen, Naprosyn, Celebrex)

NSAID (Ibuprofen, Naprosyn, Celebrex)

Gabapentin (100–300 mg po q8h) or

Gabapentin (100–300 mg po q8h) or

Pregabalin (50–150 mg po q8h)

Pregabalin (50–150 mg po q8h)

Opioid analgesics

Opioid analgesics

Morphine (5–20 mg po q4h prn)

IV infusion or prn depending pt

 

requirements

Hydromorphone (1–4 mg po q4h prn)

Morphine (−15 mg IV q1h prn)

 

Hydromorphone (0.2–1 mg IV q1–2h prn)

Add long acting opioid analgesics (introduced

Add long acting opioid analgesics (once IV

once 24 h requirements are determined and

infusion has been discontinued and 24 h oral

exceed 30 mg/24 h of morphine or 9 mg/24 h

requirements are determined and exceed

of hydromorphone)

30 mg/24 h of morphine or 9 mg/24 h of

 

hydromorphone)

MS-Contin 10–30 mg po bid/tid

MS-Contin 10–30 mg po bid/tid

Hydromorphone Contin 3–9 mg bid/tid

Hydromorphone Contin 3–9 mg bid/tid

Consider adjuncts specially in those with

Consider adjuncts specially in those with

history of illicit drug abuse and those not

history of illicit drug abuse and those not

responsive to opioids

responsive to opioids

Ketamine (10–20 mg po tid)

Ketamine (10–20 mg po tid)

Clonidine (0.1–0.2 mg po tid)

Clonidine (0.1–0.2 mg po tid)

Nabilone (1–2 mg po bid)

Nabilone (1–2 mg po bid)

 

 

Procedural analgesia/sedation

 

Consider Fentanyl IV(up to 1,000 mcg) + Midazolam IV (1–2 mg) for conscious sedation

Or

Fentanyl (up to 1,000 mcg) IV + Ketamine IV (0.5–2 mg/kg) or Propofol IV (0.5 mg/kg bolus ± 10–20 mg IV incremental boluses) for deep sedation

M.G. Jeschke et al. (eds.), Burn Care and Treatment,

183

DOI 10.1007/978-3-7091-1133-8, © Springer-Verlag Wien 2013

 

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