- •Burn Care and Treatment
- •Contents
- •1.1 Initial Assessment and Emergency Treatment
- •Box 1.1. Primary and Secondary Survey
- •1.2 Fluid Resuscitation and Early Management
- •1.2.1 Fluid Resuscitation
- •1.2.2 Endpoint of Burn Resuscitation
- •1.2.4 Role of Colloids, Hypertonic Saline, and Antioxidants in Resuscitation
- •1.2.4.1 Colloids
- •1.2.4.2 Hypertonic Saline
- •1.2.4.3 Antioxidants: High-Dose Vitamin C
- •1.3 Evaluation and Early Management of Burn Wound
- •1.3.1 Evaluation of Burn Depth
- •1.3.2 Choice of Topical Dressings
- •1.3.3 Escharotomy
- •1.3.4 Operative Management
- •References
- •2: Pathophysiology of Burn Injury
- •2.1 Introduction
- •2.2 Local Changes
- •2.2.1 Temperature and Time Effect
- •2.2.2 Etiology
- •2.2.3 Pathophysiologic Changes
- •2.2.4 Burn Size
- •2.3 Systemic Changes
- •2.3.1 Edema Formation
- •2.3.3.1 Resting Energy Expenditure
- •2.3.3.2 Muscle Catabolism
- •2.3.3.3 Glucose and Lipid Metabolism
- •2.3.4 Renal System
- •2.3.5 Gastrointestinal System
- •2.3.6 Immune System
- •2.4 Summary and Conclusion
- •References
- •3: Wound Healing and Wound Care
- •3.1 Introduction
- •3.2 Physiological Versus Pathophysiologic Wound Healing
- •3.2.1 Transforming Growth Factor Beta
- •3.2.2 Interactions Between Keratinocytes and Fibroblasts
- •3.2.3 Matrix Metalloproteinases (MMP)
- •3.3.1 Burn Wound Excision
- •3.3.2 Burn Wound Coverage
- •3.3.3 Autografts
- •3.3.4 Epidermal Substitutes
- •3.3.5 Dermal Substitutes
- •3.3.6 Epidermal/Dermal Substitutes
- •3.4 Summary
- •References
- •4: Infections in Burns
- •4.1 Burn Wound Infections
- •4.1.1 Diagnosis and Treatment of Burn Wound Infections
- •4.1.1.1 Introduction
- •4.1.2 Common Pathogens and Diagnosis
- •4.1.3 Clinical Management
- •4.1.3.1 Local
- •4.1.3.2 Systemic
- •4.1.4 Conclusion
- •4.4 Guidelines for Sepsis Resuscitation
- •References
- •5: Acute Burn Surgery
- •5.1 Introduction
- •5.2 Burn Wound Evaluation
- •5.3 Escharotomy/Fasciotomy
- •5.4 Surgical Burn Wound Management
- •5.5.1 Face
- •5.5.2 Hands
- •5.6 Treatment Standards in Burns Larger Than Sixty Percent TBSA
- •5.7 Temporary Coverage
- •5.9.1 Early Mobilisation
- •5.9.2 Nutrition and Anabolic Agents
- •Bibliography
- •6.1 Introduction
- •6.2 Initial and Early Hospital Phase
- •6.2.1 Blood Pressure
- •6.2.1.1 Resuscitation
- •6.2.1.2 Albumin
- •6.2.1.3 Transfusion
- •6.2.1.4 Vasopressors
- •6.2.2 Urine Output
- •6.2.4 Respiration
- •6.2.4.1 Ventilation Settings
- •6.2.5 Inhalation Injury
- •6.2.6 Invasive and Noninvasive Thermodilution Catheter (PiCCO Catheter)
- •6.2.7 Serum Organ Markers
- •6.3 Later Hospital Phase
- •6.3.1 Central Nervous System
- •6.3.1.1 Intensive Care Unit-Acquired Weakness
- •6.3.1.2 Thermal Regulation
- •6.3.2 Heart
- •6.3.3 Lung
- •6.3.3.1 Ventilator-Associated Pneumonia
- •6.3.4 Liver/GI
- •6.3.4.1 GI Complications/GI Prophylaxis/Enteral Nutrition
- •6.3.4.2 Micronutrients and Antioxidants
- •6.3.5 Renal
- •6.3.6 Hormonal (Thyroid, Adrenal, Gonadal)
- •6.3.7 Electrolyte Disorders
- •6.3.7.1 Sodium
- •6.3.7.2 Chloride
- •6.3.7.3 Phosphate and Magnesium
- •6.3.7.4 Calcium
- •6.3.8 Bone Demineralization and Osteoporosis
- •6.3.9 Coagulation and Thrombosis Prophylaxis
- •Conclusion
- •References
- •7.1 Introduction
- •7.2.1 Glucose Metabolism
- •7.2.2 Fat Metabolism
- •7.2.3 Protein Metabolism
- •7.3 Attenuation of the Hypermetabolic Response
- •7.3.1.1 Nutrition
- •Nutritional Route
- •Initiation of Nutrition
- •Amount of Nutrition
- •Composition of Nutrition (Table 7.1)
- •7.3.1.2 Early Excision
- •7.3.1.3 Environmental Support
- •7.3.1.4 Exercise and Adjunctive Measures
- •7.3.2 Pharmacologic Modalities
- •7.3.2.1 Recombinant Human Growth Hormone
- •7.3.2.2 Insulin-Like Growth Factor
- •7.3.2.3 Oxandrolone
- •7.3.2.4 Propranolol
- •7.3.2.5 Insulin
- •7.3.2.6 Metformin
- •7.3.2.7 Other Options
- •7.4 Summary and Conclusion
- •References
- •8.1 Introduction
- •8.2 Knowledge Base
- •8.2.1.1 Incidence
- •8.3 Aetiology and Risk Factors
- •8.3.1 Pathophysiology
- •8.3.1.1 Severity Factors
- •Box 8.1. Burn Severity Factors
- •8.3.2 Local Damage
- •8.3.3 Fluid and Electrolyte Shifts
- •8.4 Cardiovascular, Gastrointestinal and Renal System Manifestations
- •8.4.1 Types of Burn Injuries
- •8.4.1.1 Clinical Manifestations
- •Box 8.2. Primary Survey Assessment
- •Box 8.3. Signs and Symptoms of Hypovolemic Shock
- •Box 8.4. Physical Findings of Inhalation Injury
- •Box 8.5. Signs and Symptoms of Vascular Compromise
- •Box 8.6. Secondary Survey Assessment
- •8.5 Clinical Management
- •8.5.1 Nonsurgical Care
- •Box 8.7. Secondary Survey Highlights
- •Box 8.8. First Aid Management at the Scene
- •Box 8.9. Treatment of the Severely Burned Patient on Admission
- •Box 8.10. Fluid Resuscitation Using the Parkland (Baxter) Formula
- •Box 8.11. Properties of Topical Antimicrobial Agents
- •Box 8.12. Criteria for Burn Wound Coverings
- •8.5.2 Surgical Care
- •8.5.3 Pharmacological Support
- •8.5.4 Psychosocial Support
- •References
- •9.1 Electrical Injuries
- •9.1.1 Introduction
- •9.1.2 Diagnosis and Management
- •9.2 Chemical Burns
- •9.3 Cold Injury (Frostbite)
- •References
- •10.1 Introduction
- •10.2 Pathophysiology
- •10.3 Scarring
- •10.4 Therapy
- •10.5 Psychological Aspects
- •10.6 Return to Work
- •10.8 Exercise
- •10.9 Summary
- •References
- •11: Burn Reconstruction Techniques
- •11.1 From the Reconstructive Ladder to the Reconstructive Elevator
- •11.2 The Reconstructive Clockwork
- •11.2.1 General Principles
- •11.3 Indication and Timing of Surgical Intervention
- •11.4 The Techniques of Reconstruction
- •11.4.1 Excision Techniques
- •11.4.1.1 W-Plasty and Geometric Broken Line Closure
- •11.4.2 Serial Excision and Tissue Expansion
- •11.4.3 Skin Grafting Techniques
- •11.4.4 Local Skin Flaps
- •11.4.4.1 Z-Plasty
- •11.4.4.2 Double Opposing Z-Plasty
- •11.4.4.3 ¾ Z-plasty or half-Z
- •11.4.4.4 Musculocutaneous (MC) or Fasciocutaneous (FC) Flap Technique
- •11.4.5 Distant Flaps
- •11.4.5.1 Free Tissue Transfer
- •11.4.5.2 Perforator Flaps
- •11.4.6 Composite Tissue Allotransplantation
- •11.4.7 Regeneration: Tissue Engineering
- •11.4.8 Robotics/Prosthesis
- •11.5 Summary
- •References
- •Appendix
- •Sedatives and Pain Medications
- •Index
Initial Assessment, Resuscitation, |
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Wound Evaluation and Early Care |
Shahriar Shahrokhi
1.1Initial Assessment and Emergency Treatment
The initial assessment and management of a burn patient begins with prehospital care. There is a great need for efficient and accurate assessment, transportation, and emergency care for these patients in order to improve their overall outcome. Once the initial evaluation has been completed, the transportation to the appropriate care facility is of outmost importance. At this juncture, it is imperative that the patient is transported to facility with the capacity to provide care for the thermally injured patient; however, at times patients would need to be transported to the nearest care facility for stabilization (i.e., airway control, establishment of IV access).
Once in the emergency room, the assessment as with any trauma patient is composed of primary and secondary surveys (Box 1.1). As part of the primary survey, the establishment of a secure airway is paramount. An expert in airway management should accomplish this as these patients can rapidly deteriorate from airway edema.
Box 1.1. Primary and Secondary Survey
Primary survey:
•Airway:
–Preferably #8 ETT placed orally
–Always be prepared for possible surgical airway
•Breathing:
–Ensure proper placement of ETT by auscultation/x-ray
–Bronchoscopic assessment for inhalation injury
S.Shahrokhi, M.D., FRCSC
Division of Plastic and Reconstructive Surgery,
Ross Tilley Burn Centre, Sunnybrook Health Sciences Centre, 2075 Bayview Ave, Suite D716, Toronto, ON M4N 3M5, Canada e-mail: shar.shahrokhi@sunnybrook.ca
M.G. Jeschke et al. (eds.), Burn Care and Treatment, |
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DOI 10.1007/978-3-7091-1133-8_1, © Springer-Verlag Wien 2013 |
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S. Shahrokhi |
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•Circulation:
–Establish adequate IV access (large bore IV placed peripherally in nonburnt tissue if possible, central access would be required but can wait)
–Begin resuscitation based on the Parkland formula
Secondary survey:
•Complete head to toe assessment of patient
•Obtain information about the patient’s past medical history, mediations, allergies, tetanus status
•Determine the circumstances/mechanism of injury
–Entrapment in closed space
–Loss of consciousness
–Time since injury
–Flame, scald, grease, chemical, electrical
•Examination should include a thorough neurological assessment
•All extremities should be examined to determine possible neurovascular compromise (i.e., possible compartment syndrome) and need for escharotomies
•Burn size and depth should be determined at the end of the survey
Table 1.1 ABA criteria for transfer to a burn unita
1.Partial-thickness burns greater than 10 % total body surface area (TBSA)
2.Burns that involve the face, hands, feet, genitalia, perineum, or major joints
3.Third-degree burns in any age group
4.Electrical burns, including lightning injury
5.Chemical burns
6.Inhalation injury
7.Burn injury in patients with preexisting medical disorders that could complicate management, prolong recovery, or affect mortality
8.Any patient with burns and concomitant trauma (such as fractures) in which the burn injury poses the greatest risk of morbidity or mortality. In such cases, if the trauma poses the greater immediate risk, the patient may be initially stabilized in a trauma center before being transferred to a burn unit. Physician judgment will be necessary in such situations and should be in concert with the regional medical control plan and triage protocols
9.Burned children in hospitals without qualified personnel or equipment for the care of children
10. Burn injury in patients who will require special social, emotional, or rehabilitative intervention
aFrom Ref. [1]
Once this initial assessment is complete, the disposition of the patient will be determined by the ABA criteria for burn unit referral [1] (Table 1.1).
In determining the %TBSA (% total body surface area) burn, the rule of 9 s can be used; however, it is not as accurate as the Lund and Browder chart (Fig. 1.1) which further subdivides the body for a more accurate calculation. First-degree burns are not included.
1 Initial Assessment, Resuscitation, Wound Evaluation and Early Care |
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A |
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A |
Region |
Partial thickness (%) [NB1] |
Full thickness (%) |
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head |
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1 |
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neck |
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anterior trunk |
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13 |
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posterior trunk |
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2 |
2 |
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2 |
2 |
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right arm |
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left arm |
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11/2 |
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11/2 |
11/2 |
11/2 |
buttocks |
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11/2 |
1 |
11/2 |
21/2 |
21/2 |
genitalia |
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11/2 |
11/2 |
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B |
B |
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B |
B |
right leg |
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left leg |
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Total burn |
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NB1 : Do not include erythema |
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C |
C |
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C |
C |
Area |
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Age 0 |
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5 |
10 |
15 |
Adult |
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A = half of head |
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91/2 |
81/2 |
61/2 |
51/2 |
41/2 |
31/2 |
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13/4 |
13/4 |
B = half of one thigh |
23/4 |
31/4 |
4 |
41/2 |
41/2 |
43/4 |
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13/4 |
13/4 |
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C = half of one lower leg |
21/2 |
21/2 |
23/4 |
3 |
31/4 |
31/2 |
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Fig. 1.1 Lund and Browder chart for calculating %TBSA burn |
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Table 1.2 Typical clinical appearance of burn depth |
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First-degree burns |
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Involves only the epidermis and never blisters |
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Appears as a “sunburn” |
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Is not included in the %TBSA calculation |
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Second-degree burns (dermal burns) |
Superficial |
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Pink, homogeneous, normal cap refill, painful, moist, |
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intact hair follicles |
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Deep |
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Mottled or white, delayed or absent cap refill, dry, |
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decreased sensation or insensate, non-intact hair |
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follicles |
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Third-degree burns |
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Dry, white or charred, leathery, insensate |
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Assessment of burn depth can be precarious even for experts in the field. There are some basics principles, which can help in evaluating the burn depth (Table 1.2). Always be aware that burns are dynamic and burn depth can progress or convert to being deeper. Therefore, reassessment is important in establishing burn depth.
Given that even burn experts are only 64–76 % [2] accurate in determining burn depth, there has been an increased desire to have more objective method of determining burn depth, and therefore, technologies have been and continue to be developed and utilized in this field. These are summarized in the following Table 1.3 [3]:
Once the initial assessment and stabilization are complete, the physician needs to determine the patient’s disposition. Those that can be treated as outpatient (do not
4 |
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S. Shahrokhi |
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Table 1.3 Techniques used for assessment of burn deptha |
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Technique |
Advantages |
Disadvantages |
Radioactive isotopes |
Radioactive phosphorus (32P) |
Invasive, too cumbersome, poorly |
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taken up by the skin |
reproducible |
Nonfluorescent dyes |
Differentiate necrotic from |
No determination of depth of |
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living tissue on the surface |
necrosis; many dyes not approved |
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for clinical use |
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Fluorescent dyes |
Approved for clinical use |
Invasive; marks necrosis at a fixed |
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distance in millimeters, not |
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accounting for thickness of the skin; |
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large variability |
Thermography |
Noninvasive, fast assessment |
Many false positives and false |
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negatives based on evaporative |
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cooling and presence of blisters; |
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each center needs to validate its own |
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values |
Photometry |
Portable, noninvasive, fast |
Single-institution experience; |
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assessment, validated against |
expensive? |
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senior burn surgeons, and color |
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palette was developed |
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Liquid crystal film |
Inexpensive |
Contact with tissue required, |
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unreliable readings |
Nuclear magnetic |
Water content in tissue |
resonance |
differentiates partial from |
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full-thickness wounds |
In vitro assessment only, expensive, time-consuming
Nuclear imaging |
99mTc shows areas of deeper |
Expensive, very time-consuming, |
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injury |
not readily available, and invasive |
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Pulse-echo ultrasound |
Noninvasive, easily available |
Underestimates depth of injury, |
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operator-dependent, and requires |
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contact with tissue |
Doppler ultrasound |
Noncontact technology |
Operator-dependent, not as reliable |
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available, provides morpho- |
as laser Doppler |
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logic and flow information |
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Laser Doppler imaging |
Noninvasive and noncontact |
Readings affected by temperature, |
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technology, fast assessment, |
distance from wound, wound |
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large body of experience in |
humidity, angle of recordings, extent |
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multiple centers, and very |
of tissue edema, and presence of |
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accurate prediction in small |
shock; different versions of the |
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wounds in stable patients |
technology available make |
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extrapolation of results difficult |
aFrom Jaskille et al. [3] |
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meet burn unit referral criteria) will need their wounds treated appropriately. There are many choices for outpatient wound therapy, and the choice will be mostly dependent on the availability of products and physician preference/knowledge/comfort with application. Table 1.5 summarizes some of the available products.
The thermally injured patients who are transferred to burn units for treatment will be discussed in the next section on fluid resuscitation and early management.