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640 CHAPTER 16 Urological surgery and equipment

Ileal conduit

Indications

For urinary diversion following radical cystectomy

Intractable incontinence for which anti-incontinence surgery has failed or is not appropriate

Postoperative care and common postoperative complications and their management

Oliguria or anuria: Try a fluid challenge.

Wound infection: Treat with antibiotics and wound care. Open the superficial layers of the wound to release pus.

Wound dehiscence is rare. It requires resuturing in the operating room, under general anesthetic.

Ileus is common. It usually resolves spontaneously within a few days.

Small bowel obstruction

This occurs from herniation of small bowel through the mesenteric defect created at the junction between the two bowel ends. Continue nasogastric aspiration. The obstruction will usually resolve spontaneously.

Reoperation is occasionally required when the obstruction persists or there are signs of bowel ischemia.

Leakage from the intestinal anastomosis

This can lead to the following:

Peritonitis—requiring reoperation and repair or refashioning of the anastomosis

An enterocutaneous fistula—bowel contents leak from the intestine and through a fistulous track onto the skin. A low-volume leak (<500 mL/24 hr) will usually heal spontaneously. Normal (enteral) nutrition may be maintained until the fistula closes (which usually occurs within a matter of days or a few weeks). If high volume, spontaneous closure is less likely, and reoperation to close the fistula may be required.

Leakage from the ureteroileal junction

Leakage may be suspected because of a persistently high output of fluid from the drain. Test this for urea. Urine will have a higher urea and creatinine concentration than serum. If the fluid is lymph, the urea and creatinine concentration will be the same as that of serum.

Arrange for a loopogram. This will confirm the leak. Place a soft, small catheter (12 Fr) into the conduit to encourage antegrade flow of urine and assist healing of the ureteroileal anastomosis. If the leakage continues, arrange for bilateral nephrostomies to divert the flow of urine away from the area and encourage wound healing.

Occasionally, a ureteroileal leak will present as a urinoma (this causes a persistent ileus). Radiologically assisted drain insertion can result in a dramatic resolution of the ileus, with subsequent healing of the ureteroileal leak.

ILEAL CONDUIT 641

Hyperchloremic acidosis

This may be associated with obstruction of the stoma at its distal end or from infrequent emptying of the stoma back (leading to back-pressure on the conduit). Catheterize the stoma relieves the obstruction. In the long term, the conduit may have to be surgically shortened.

Acute pyelonephritis is due to the presence of reflux combined with bacteriuria.

Stomal stenosis

The distal (cutaneous) end of the stoma may become narrowed, usually as a result of ischemia to the distal part of the conduit. Revision surgery is required if this stenosis causes obstruction leading to recurrent UTIs or back-pressure on the kidneys.

Parastomal hernia formation

Hernias occur around the site through which the conduit passes, through the fascia of the anterior abdominal wall. Many hernias can be left alone. The indications for repairing a hernia are as follows:

Bowel obstruction

Pain

Difficulty with applying the stoma bag (distortion of the skin around the stoma by the hernia can lead to frequent bag detachment).

Repair the hernia defect by placing mesh over the hernia site, via an incision sited as far as possible from the stoma itself, to reduce the risk of wound infection.

Procedure-specific consent form—recommended discussion of adverse events

Serious or frequently occurring complications of ileal conduit formation

Common

Temporary drain, stents, or nasal tube

Urinary infections, occasionally requiring antibiotics

Occasional

Diarrhea due to shortened bowel

Blood loss requiring transfusion or repeat surgery

Infection or hernia of incision requiring further treatment

Rare

Bowel and urine leakage from anastomosis requiring reoperation

Scarring to bowel or ureters requiring operation in future

Scarring, narrowing, or hernia formation around urine opening requiring revision

Decreased renal function with time

Alternative treatment includes catheters, continent diversion of urine.

642 CHAPTER 16 Urological surgery and equipment

Percutaneous nephrolithotomy (PCNL)

Indications

Stones >3 cm in diameter

Stones that have failed ESWL and/or an attempt at flexible ureteroscopy and laser treatment

Staghorn calculi

Preoperative preparation

CT scan to assist planning the track position and to identify a retrorenal colon1

Stop aspirin 10 days prior to surgery

Culture urine (so appropriate antibiotic prophylaxis can be given)

Cross-match 2 units of blood

Start IV antibiotics the afternoon before surgery to reduce the chance of septicemia (many stones treated by PCNL are infection stones). If urine is culture negative, use 1.0 g IV ampicillin and IV gentamicin (1.5 mg/kg). Routine antibiotic prophylaxis also reduces the incidence of postoperative UTI.2

Postoperative management

Once the stone has been removed, a nephrostomy tube is left in situ for several days (Fig. 16.15). This drains urine in the postoperative period and tamponades bleeding from the track.

Complications of PCNL and their management

Bleeding

Some bleeding is inevitable, but an amount severe enough to threaten life is uncommon. In most cases it is venous in origin and stops following placement of a nephrostomy tube (which compresses bleeding veins in the track).

If bleeding persists, clamp tube for 10 minutes. If bleeding continues despite this, order urgent angiography, looking for an arteriovenous fistula or pseudoaneurysm, both of which require selective renal artery embolization (required in 1% of PCNLs3) or open exposure of kidney to control bleeding by suture ligation, partial nephrectomy, or nephrectomy.

Septicemia

This occurs in 1–2% of cases. Incidence is reduced by prophylactic antibiotics. Track damage; it is essentially minimal. Cortical loss from track is estimated to be <0.2% of total renal cortex in animal studies.4

1 Hopper KD, Sherman JL, Williams MD, et al. (1987). The variable anteroposterior position of the retroperitoneal colon to the kidneys. Invest Radiol 22:298–302.

2 Inglis JA, Tolly DA (1988). Antibiotic prophylaxis at the time of percutaneous stone surgery. J Endourol 2:59–62.

3 Martin X (2000). Severe bleeding after nephrolithotomy: results of hyperselective embolisation. Eur Urol 37:136–139.

PERCUTANEOUS NEPHROLITHOTOMY (PCNL) 643

Figure 16.15 A Malecot catheter, which has wide drainage eyeholes and an extension at the distal end which passes down the ureter to prevent fragments of stone from passing down the ureter.

Colonic perforation

The colon is usually lateral or anterolateral to the kidney and is therefore not usually at risk of injury unless a very lateral approach is made. The colon is retrorenal in 2% of individuals (more commonly in thin females with little retroperitoneal fat1).

The perforation usually occurs in an extraperitoneal part of the colon and is managed by JJ stent placement and withdrawal of the nephrostomy tube into the lumen of the colon to encourage drainage of bowel contents away from that of the urine, thereby encouraging healing without development of a fistula between the bowel and kidney.

A radiological contrast study a week or so later confirms that the colon has healed and that there is no leak of contrast from the bowel into the renal collecting system.

Damage to the liver or spleen is very rare in the absence of splenomegaly or hepatomegaly.

4 Clayman J (1987). Percutaneous nephrostomy: assessment of renal damage associated with semirigid (24F) and balloon (36F) dilation. J Urol 138:203–206.

644 CHAPTER 16 Urological surgery and equipment

Damage to the lung and pleura leading to pneumomothorax or pleural effusion can occur with supra-12th rib puncture.

Nephrocutaneous fistula

When the nephrostomy tube is removed from the kidney, a few days after surgery, the 1 cm incision usually closes within 2 days or so.

Occasionally, urine continues to drain percutaneously for a few days and a small stoma bag must be worn. In most of these cases the urine leak will stop spontaneously, but if it fails to do so after a week or so, place a JJ stent to encourage antegrade drainage of urine.

Outcomes

For small stones, the stone-free rate after PCNL is on the order of 90–95%. For staghorn stones, the stone-free rate of PCNL, when combined with postoperative ESWL for residual stone fragments, is on the order of 80–85%.

Procedure-specific consent form—recommended discussion of adverse events

Serious or frequently occurring complications of PCNL

Common

Temporary insertion of a bladder catheter and ureteric stent or kidney tube needing later removal

Transient hematuria

Transient temperature

Occasional

More than one puncture site may be required

No guarantee of removal of all stones and need for further operations

Recurrence of stones

Rare

Severe kidney bleeding requiring transfusion, embolization, or, at last resort, surgical removal of kidney

Damage to lung, bowel, spleen, or liver requiring surgical intervention

Kidney damage or infection needing further treatment

Overabsorption of irrigating fluids into the blood system, causing strain on heart function

Alternative treatment includes external shock wave treatments, open surgical removal of stones, observation.

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