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Chapter 16

571

 

 

Urological surgery and equipment

Preparation of the patient for urological surgery 572 Antibiotic prophylaxis in urological surgery 574 Complications of surgery in general: DVT and PE 576 Fluid balance and management of shock in the surgical

patient 580

Patient safety in the operating room 582 Transurethral resection (TUR) syndrome 583 Catheters and drains in urological surgery 584 Guide wires 590

Irrigating fluids and techniques of bladder washout 592 JJ stents 594

Lasers in urological surgery 598 Diathermy 600

Sterilization of urological equipment 604

Telescopes and light sources in urological endoscopy 606 Consent: general principles 608

Cystoscopy 610

Transurethral resection of the prostate (TURP) 612 Transurethral resection of bladder tumor (TURBT) 614 Optical urethrotomy 616

Circumcision 618

Hydrocele and epididymal cyst removal 620 Nesbit procedure 622

Vasectomy and vasovasostomy 624 Orchiectomy 626

Urological incisions 628 JJ stent insertion 630

Nephrectomy and nephroureterectomy 632 Radical prostatectomy 634

Radical cystectomy 636 Ileal conduit 640

Percutaneous nephrolithotomy (PCNL) 642 Ureteroscopes and ureteroscopy 646 Pyeloplasty 650

Laparoscopic surgery 652

Endoscopic cystolitholapaxy and (open) cystolithotomy 654 Scrotal exploration for torsion and orchiopexy 656

572 CHAPTER 16 Urological surgery and equipment

Preparation of the patient for urological surgery

The degree of preparation is related to the complexity of the procedure. Certain aspects of examination (pulse rate, blood pressure) and certain tests (hemoglobin, electrolytes, and creatinine) are important not only to assess fitness for surgery but also as a baseline against which changes in the postoperative period may be measured.

Assess cardiac status (angina, arrhythmias, previous myocardial infarction [MI], blood pressure, electrocardiogram [ECG], chest X-ray [CXR]). We assess respiratory function by pulmonary function tests (forced vital capacity [FVC], forced expiratory volume in 1 second

[FEV1]) for all major surgery and for any surgery where the patient has symptoms of respiratory problems or a history of chronic airways disease (e.g., asthma).

Arrange an anesthetic review when there is, for example, cardiac or respiratory comorbidity.

Culture urine, treat active (symptomatic) infection with an appropriate antibiotic starting a week before surgery, and give prophylactic antibiotics at the induction of anesthesia.

Stop aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs) 10 days prior to surgery.

Obtain consent (see p. 608).

Measure hemoglobin and serum creatinine and investigate and correct anemia, electrolyte disturbance, and abnormal renal function. If blood loss is anticipated, group and save a sample of serum or cross-match several units of blood, the precise number depending on the speed with which your blood bank can deliver blood if needed. Recommendations on blood products are as follows:

TURBT

Type and hold

TURP

Cross-match 2 units

Open prostatectomy

Cross-match 2 units

Simple nephrectomy

Cross-match 2 units

Radical nephrectomy

Cross-match 4 units

Cystectomy

Cross-match 4 units

Radical prostatectomy

Cross-match 2 units

PCNL

Cross-match 2 units

 

 

The patient may choose to store his or her own blood prior to the procedure.

Bowel preparation

This is indicated if bowel is to be used (ileal conduit, bladder reconstruction). Use a mechanical prep (Fleets phosphasoda or polyethelen glycol 3350) and antimicrobial prep (neomycin and erythromycin base), starting at noon the day before surgery, with a clear fluid-only diet for the rest of the day.

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574 CHAPTER 16 Urological surgery and equipment

Antibiotic prophylaxis in urological surgery

The precise antibiotic prophylaxis policy that you use will depend on your local microbiological flora. Your local microbiology department will provide regular advice and updates on which antibiotics should be used, both for prophylaxis and treatment. The policy shown below and in Table 16.1 is just a recommendation.

Culture urine before any procedure, and use specific prophylaxis (based on sensitivities) if culture positive.

We avoid ciprofloxacin in inpatients because it is secreted onto the skin and causes methicillin-resistant Staphylococcus aureus (MRSA) colonization. For most purposes, nitrofurantoin provides equivalent coverage without being secreted onto the skin.

We do use ciprofloxacin if there is known Proteus infection (all Proteus species are resistant to nitrofurantoin).

Patients with artificial heart valves

Patients with heart murmurs and those with prosthetic heart valves should be given 1 g IV amoxycillin with 80 mg gentamycin at induction of anesthesia, with an additional dose of oral amoxycillin, 500 mg 6 hours later (substituting vancomycin 1 g for those who are penicillin allergic).

Patients with joint replacements

The advice is conflicting.

AAOS/AUA advice

Joint advice of the American Academy of Orthopedic Surgeons (AAOS) and the American Urological Association (AUA) is that antibiotic prophylaxis is not indicated for urological patients with pins, plates, or screws, nor for most patients with total joint replacements.

It is recommended for all patients undergoing urological procedures, including TURP, within 2 years of a prosthetic joint replacement, for those who are immunocompromised (e.g., rheumatoid patients, those with systemic lupus erythematosus [SLE], drug-induced immunosuppression, including steroids), and for those with a history of previous joint infection, hemophilia, HIV infection, diabetes, or malignancy.

Antibiotic regime

Give a single dose of a quinolone, such as 500 mg of ciprofloxacin, 1–2 hours preoperatively + ampicillin 2 g IV + gentamicin 1.5 mg/kg 30–60 minutes preoperatively (substituting vancomycin 1 g IV for penicillin-allergic patients).

ANTIBIOTIC PROPHYLAXIS IN UROLOGICAL SURGERY 575

Table 16.1 Oxford urology procedure: specific antibiotic prophylaxis protocol for urological surgery

Procedure

Antibiotic prophylaxis

Catheter removal

Nitrofurantoin, 100 mg PO 30 min

 

before catheter removal

Change of male long-term catheter

Gentamicin 1.5 mg/kg IM or IV 20 min

 

before*

Flexible cystoscopy or GA cystoscopy

Nitrofurantoin 100 mg PO 30–60 min

 

before procedure

Transrectal prostatic biopsy

Ciprofloxacin 500 mg PO 30 min

 

pre-biopsy and for 48 hr post-biopsy

 

(ciprofloxacin 500 mg bid)

ESWL

500 mg oral ciprofloxacin 30 min

 

before treatment (nitrofurantoin does

 

not cover Proteus, a common stone

 

bacterium)

PCNL

Ampicillin 1 g + IV gentamicin

 

at induction (1.5 mg/kg);

 

before operation, and 2 doses

 

postoperatively

Ureteroscopy

Urogynecological procedures (e.g., colposuspension)

TURPs and TURBTs — both for non-catheterized patients (i.e., elective TURP for LUTS) and patients with catheters (undergoing TURP for retention)

Gentamycin 1.5 mg/kg IV at induction

Cefuroxime 1.5 g IV and metronidazole 500 mg IV at induction of anesthesia

Ampicillin 1 g + IV gentamicin at induction (1.5 mg/kg); nitrofurantoin 100 mg PO 30 min before catheter removal

Radical prostatectomy

Cystectomy or other procedures involving the use of bowel (e.g., augmentation cystoplasty)

Artificial urinary sphincter insertion

Ampicillin 1 g + IV gentamicin at induction (1.5 mg/kg); before operation

Ampicillin 1 g + IV gentamicin at induction (1.5 mg/kg); before operation

Vancomycin 1 g 1.5 hr before leaving the ward (infuse over 100 min) + 1.5 mg IV cefuroxime + 3 mg/kg IV gentamicin at induction; continue

IV cefuroxime, gentamicin, and vancomycin (1 g) for 48 hr

*Sepsis rate (necessitating admission to hospital) may be as high as 1% without antibiotic coverage.

Note: Cefuroxime has a short half-life. Whenever using cefuroxime, give a further dose 2 hours after the first dose. Further intraoperative top-up doses of vancomycin and gentamicin are not required as they have long half-lives.