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Administration

General Principles

An i njection s ite is the reaa o f a limbwhere a vaccination can be gveni. There are num erous injection sites i n e ach limb, f or example the m iddle a nterior surface of the f orearm, the m iddle third of the posterolateral surface of the arm, the upper third of the arm, theexternal anterolateral area of the thigh, and the vastuslateralis muscle.

Immunizing a gents m ust be gi ven using t he a dministration r oute i ndicated i n t he a ppropriate chapter.

Immunizing a gents s hould not be injected where there is inflammation, itching, rs,scanodules, sensitivity, induration, pain, or blood vessels.

Whenever possible, avoid administering an immunizing agent in a limb that is likely to be affected by a lymphatic system problem, such as lymphedema or mastectomy with lymph node curettage.

However, if

he patitis B nda rabies

vaccines are

i ndicated, even

i n

the c ase of a

bralilate

mastectomy, the agent should be administered in the deltoid muscle.

 

 

 

Intradermal

( ID) i njections must be

d one operlyr

i n t he de rma,

s ince

s mall q uantities

of t he

agent’s antigen are used. If the agent is inadvertently administered subcutaneously, the result will be suboptimal immune response.

A good intramuscular (IM) injection technique is important for the following reasons: –Injecting the agent into adipose tissue could adversely affect the immune response.

–Vaccines containing adjuvants administered subcutaneously or intradermally can cause irritation, induration, a change in skin colouring, inflammation, or the formation of granuloma at the site.

Hepatitis B and rabies vaccines must be injected into the deltoid muscle in persons 1 year of ageor older. For c hildren u nder 1 year o f age, t he vastus lateralis muscle is u sed t o a dminister these

vaccines. It ha s be en s hown that the immunogenicity

of thesevaccines i s s ubstantially lowered

when t hey are a dministered

into t he gl uteal muscle, as

co mpared

with t he deltoid. This c an be

explained by t he f act t hat

thevaccine may have p ossibly be en

inadvertently a dministered i nto

adipose tissue, instead of the muscle tissue. Any hepatitis B or rabies vaccines administered into the gluteal muscle should be considered not given and should be readministered in the deltoid muscle.

If several injections are to be given at the same visit, consideration could be given to administering two injections at thesame site. This means that 2IM injections, or1 IM and 1 SC injection, or 2 SC injections could be given at the same site (deltoid muscle or vastus lateralis muscle). The distance between injections should be at least 2.5cm (1inch) so that local reactions can be distinguished for each product administered and immune interference prevented.

Nova Scotia Immunization Manual—Chapter 8 :Immunization Techniques

3

Intradermal (ID)Injections

Definition

The introduction into the derma of a minimal amount (between 0.01and 0.1 mL) of biological product; it is used for tuberculin skin test (TST) administration.

Site and needle size for ID injections

Use a 1 mL TB syringe and 27-gauge needle of ½" length.

The usual site for intradermal injections is the flexor surface of the forearm.

Have client rest their arm on a firm surface, forearm turned up.

Because of t he d ecreased a ntigenic m ass administered wit h I D injections, attention to technique is essential to ensure that the material is not injected subcutaneously.

Procedure

 

 

 

Important Pointes

 

1. Select the injection site; palpate the area to ensur

Normal Site

 

that the tissue is intact.

 

 

for the tuberculin skin test (TST, previously known as PPD):

 

 

 

 

middle anterior surface of forearm

 

 

 

 

for rabies vaccine used for pre-exposure: upper third of arm

When

a dministering t he

TST,

a sk t he us erThist o way, the injectionsite does not move and is easier to reach.

extend their arm and press their elbow and forearm

Also, relaxing reduces distress for the user.

against the table.

 

 

 

 

When

administering rabies

v accine

preexposure,-

In the case of a child, the provider holds the child’s arm with the

ask the user to relax the limb.

 

left hand so that the left hand is underneath the child’s arm a nd

 

 

 

 

the thumb and fingers surround the arm and stretch the skin.

2.Clean the site with an alcohol swab using a circular Allow the site to dry in order to prevent the user from feeling

outward motion from the centre, describing a circle burning sensation when the needle enters. approximately 5 cm in diameter.

3.Hold t he s kin i n t he s elected a rea be tween thumb and index finger.

4

Nova Scotia Immunization Manual—Chapter 8: Immunization Techniques

Nova Scotia Immunization Manual—Chapter 8: Immunization Techniques

5

Subcutaneous (SC) Injections

Definition

The introduction of an immunizing agent into the connective tissue layer beneath the skin.

Procedure

Important Points

 

1. Select the injection site; palpate the area

Customary sites for vaccination are the middle

 

to ensure that the tissue is intact.

third of t he p osterolateral s urface o f t he ar m

 

the de ltoid a rea a nd t he e xternal a nterolateral

 

area of the thigh.

2.Clean the s ite with a n a lcohol s

using

a

c ircular

o utward motion

f rom

the

c

entre,

d escribing

a

approximately 5 cm in diameters.

 

3.

4.Pinch t he s kin between t he thumb a n index fingers to raise the subcutaneous tissue.

5.Release the skin.

6.Inject the immunizing agent.

7.Withdraw t he ne edle a nd a pply sghtli

pressure to

the

injection

site

with a

cotton s wab

or

c ompress,

but

d o not

massage.

 

 

 

 

8.Dispose of s oiled e quipment i n container provided for that purpose.

6

Nova Scotia Immunization Manual—Chapter 8: Immunization Techniques

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