MONGOLIAN SPOT

•Most frequently seen pigmented lesion.

•Collections of melanocytes located in the dermis.

•Benign, blue-gray or blue-black patches, located over the sacrum.

•The blue colour of dermal melanosis is due to the Tyndall effect

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•Cause-arrested embryonal migration of melanocytes from neural crest to epidermis resulting in dermal melanocytosis

•Lesions range from a few millimeters to more than 10 cm and may be single or multiple.

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•Lesions also occur on the buttocks, dorsal trunk and extremities.

•Lesion colour stabilizes in infancy, and the lesion disappears in almost all patients before puberty.

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SEBACEOUS GLAND HYPERPLASIA

•Tiny monomorphous pinhead-sized lesions, white or yellow in color, seen over the nose, upper lip, malar region, forehead and chin.

•Manifestation of maternal androgen stimulation.

•Represent hyperplastic sebaceous glands and fade in the first few weeks of life.

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MILIA

•About 40% of neonates have multiple, pearly white, or yellow papules, 1-3 mm in size, scattered over the cheeks, nose, nasolabial folds, forehead, rarely over the foreskin.

•Histologically-follicular epidermal cysts that contain laminated keratin.

•Disappear-within first month of life.

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MILIA

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DESQUAMATION (PHYSIOLOGICAL SCALING OF

NEWBORN)

•Transepidermal water loss- leads to skin peeling which is called as physiologic desquamation (PD).

•In excessive desquamation, it may be confused with congenital ichthyosiform disorders.

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