Иммунопрофилактика инфекционных болезней

8.3 CpoK"1 pa3B"1T"1S1 nOCTBaKU."1HanbHblX peaKU."1H ..., OC110>KHeH"1Vt Ha

np"1B"1BK"1, KOTOpble npOBOAS1TCS1 Ha 3HAeM"14HblX ..., 3H300T"14Hb1X

Tepp"1TOp"1S1X no 3n"1AeM"14eCKl1M noKa3aHl.1S1M.

29

8.4 ct>opMa no.a.a4111 111HcpopMau,111111 o cnyyae no6o'-1HoroAei1cTe1..u1 (ocno>t<HeH111S1) noc.ne np111MeHeH111S1 1t1MMyH06111011or111'-lecK111xnpenapaToe.

nocTBaKL.J,VIHaJlbHble peaKL.J,111111 VI OCllO>KHeHVls=! - 3TO HapyweHVls:l 3,D.OpOB bs=!, KOTOpble B03Hll1KalOT nocne VIMMYHV13aLJ,1111!1 BCJle,D.CTBVle ee npoBe,O.eHVls=I. npo Ka>KAblVJ c11yL1at71 oc110>1<HeHV1ri nocne np111MeHeH11rn 6aKrep111i::iHoro, s111pycHoro 11111111 CblBopoTOL!Horo npenapara, woKa, cMepT111 nocne sBe,o.eH111s=i npenapara, no60L!HOVJ peaKLJ,1!1111 11111111 nOBblWeHHOVl peaKTOreHHOCTll1 npenapaTa 0611aCTHble

111HcpopMau,111111 c Mecra.

Ka>1<,o.b1Vi cnyLtatll oc110>1<HeH111s:i (11111111 no,o.03peH111s=i Ha oc110>1<HeH111e) nocne BaKL.J,111HaLJ,1111!1 nogJle>KVIT perl!ICTpaL.J,VIVI 111 paccne.o.osaHll1IO. n o pe3yllbTaTaM paccne.o.osaH111s=i cocTas11s=ier cs=i aKT paccne,o.osaH111ri no6oYHoro ,o.eVicTsl!1s=i (oc110>1<HeH111s=i) nocne saKL.J,111Hau.111111, KOTOpb1Vi .o.on>KeH co,o.ep>KaTb c11e,o.y10w,V1e pa3,o.e11b1:

1. ct>. , Vl., 0. li111cno, Mecriu., ro.o. po>1<,o.eH111s:i . Mecro pa 6oTbl (,o.eTcKoe yYpe>1<JJ,eHV1e). Mecro >1<111renbcrsa.

2.OpraH1113au,111H, KoropaH paccne,o.osana ( Bb1s=is11111a) cnyYaVi no6oYHoro ,o.eVicTs111s=i (oc110>KHeH111H nocne np111MeHeH111 s=i) 111MMyH06111011or111YecKoro npenapara.

3.Cse,o.eH111H o npenapare.

Ha111MeHosaHV1e npenapara. Cep111s=i. KoHrpo11bHb1Vi HOMep. CpoK ro,o.Hocr111. npe,o.np111Hr111e-npo1113so,o.111renb. B KaKOM Kon111Yecrse nonyYeH npenapar. )J,ara

30

no11yYeH111A. Yc11os11rn 111 TeMnepaTypHblLll pe>KlllM xpaHeHVIA s 0611acT111, paLlioHe, ropo,o,e np111MeHeH111s:i.

HapyweHvie npou,e,n,ypbl saKLJ,111HaU,l!ll!1 (MeTo,o,a sse,n,eH111A, ,LJ,03bl, yc11os111111 xpaHeH111A, 1113 pacKpblTOill aMnyllbl 111 T. ,0,.).

Ko11V1YecTso 11111u, np111s111Tb1x ,n,aHHoLll cep111eLI! B paLlioHe, 0611acr111 11111111 KOlll!lLJecTBO 111cno11b30BaHHblX ,0,03 npenapara.

Konl!lLJecrso y np111s111TblX Heo6b1LJHblX peaKu,111LI! Ha saKu,111Hau,11110. 4. Cse,n,eHVIA npo COCTOAHVle 3,0,0pOBbA np111s111roro.

.QaTa BaKLJ,V1HaLJ,vH1. KeM 6blll OCMOTpeH nepe,n, BaKLJ,ll1Hau.111eLI! (spaYOM, cpenb,LJ,WepoM, Me,n,cecrpoilt); TeMneparypa nepe,n, saKU,111HaLJ,l!leilt.

V1H.0,111B111,LJ,YallbHble oco6eHHOCTl/1 (He.O,OHOWeHHOCTb, po,n,osaA rpasMa, LJepenHO-M03rosaA rpaBMa, repan111A KOpTV1KOCTepo111,n,aMl!1, KOTOpaA npe,LJ,WeCTBOBana BaKLJ,111HaLJ,111111 Ill T. .0,.) .

nepeHeCeHHble 3a6oneBaHll1A (,LJ,nA ,LJ,eTelli nepBblX 3x neT >KV13HVI C yKa3aHll1eM

.o,aTbl 111 ,LJ,n111renbHocr111 3a6onesaHl!1A); yKa3aTb ,IJ,aTy 111 ,IJ,n111TeJlbHOCTb nocne,IJ,Hero 3a6onesaHV1A.

3a6onesaH111A a11neprw-1ecKoro xapaKrepa (s T. LJ. Ha . Me,n,111KaMeHTbl 111 n111~eBble npOAYKTbl) .

Ha11111LJ111e cy,n,opor s npownoM y saKL.J,111Hl!lposaHHoro, ero po,IJ,111TeneLll, 6parbeB 111 cecrep, np111 nosb1weH111111 reMneparypbl 11111111 6e3 Hee, KaK ,IJ,asHo.

npose,o,eHHble np111Bl/1BKVI C yKa3aHl!leM ,LJ,aT BBe,LJ,eHlllA npenapara: 6U>K-saKu,111Ha, AK.QC-saKLJ,l!lHa, A.QC-aHaTOKC111H, A.QC-M-aHaTOKCll1H, n0111110Ml!leJ11!1THaA, KopesaA, napOTl!lTHaA BaKLJ,lllHa 111 T.

Ha6n10.o,an111cb n111 y np111s111roro 11111111 ero 6n1113Kl!1X po,n,crseHH111kos Heo6b1YHb1e peaKu,111111 Ha np111s111BKl!l (KaK111e, xapaKrep peaKu,111ilt) .

,IJpnOJlHl!lTeJlbHble ,n,aHHble (KOHTaKT c 111HcpeKL.J,1!10HHblMl!l 60JlbHblMl/1 B ceMbe, ,IJ,eTCKOM yype>K,IJ,eHl!1111, nepeoxna>K,IJ,eH111e 111 r. ,IJ,.) .

5. Kn111Hl!lLJecKoe reYeHl!1e.

.Qara 3a6011esaHl!1A, >Kano6b1. Dara o6pa~eHl!1A. 06beKTl!1BHo: Cl!lMnroMbl MecrHoLll 111 o6~eLI! peaKu,111lll, ,LJ,ll1arHo3. .Qara 111 Mecro rocn111Tan1113au,V1111. TeYeH111e 3a6onesaHl/15i (KopOTKO). 3aKn!OYll1TellbHbllli ,o,111arH03: OCHOBHOill, OCllO>KHeHVIA, conyrcrsy!O~l!le 3a6onesaH111A. .QaTa Bb1n111cK111. Pe3y11brar. OcraroLJHble ABJleHVIA.

B c11yyae cMepr111: .Qara naronoroaHaToM111YecKoro ,n,111arH03a. 6. BblBO,D, KOM111CCl!11!1 npo np111LJll1Hbl OCllO>KHeHvrn.

D.oll>KHOCTl/1 111 no,LJ,nlllCl!l LJJleHOB KOMll1CCll1111 . .QaTa 06c11e,IJ,OBaHl!1A. 3KCTpeHHOe 1113se~eH111e noenaHO no re11ecp0Hy, renerpacpy ( no,IJ,LJepKHYTb ). .Qara.

np111 HanpasneHl/11!1 aKTa paccne,o,osaHll1A B MlllHl!lCTepcTBO oxpaHbl 3,D,OpOBbA YKpa111Hbl 111 rocy,o,apcrseHHoe npe,D,np1115n111e «UeHrp 111MMyH06111onor111LJecK111x npenaparos» o65i3arenbHO yKa3b1saeTCA Ha3BaH111e opraH1113aL.J,111111, Koropa51 Hanpas111na l!lHcpopMau,11110, a TaK>Ke ee MecT0Haxo>1<,o,eH111e.

·~r 31

9. IOpHAM'-leCKMeacneKTbl MMMyHonpoct>MnaKTMKH.

Bee np111s111sK111, soweAw111e s np111Ka3 N~ 595 M03 YKpa111Hb1, flBJlHIOTOl o6H3aTeJlbHblMll1. B AOnOJ1HeHll1111 K HlllM np111 B03Hll1KHOBeHll1111 Ype3Bbl'-lati!HblX 0 1nyau,111tii o6H3arenbHblMlll Moryr 6b1Tb o6bHBJleHbl 111 ps:iA Apyr111x np111s111soK.

065BaTeJlbHbl np111Bll1BKll1 Afls:l HeKOTOpblX npocpecc1110HaJlbHblX rpynn B cnyyae nOBblWeHHOro p111CKa lllHcpeKU,111111 AJlH pa60THll1Ka, KOHTaKT111pyiow,ero c 111croLJH111KoM, a raK>Ke np111 onacHocr111 Maccosoro pacnpocrpaHeH111H 111HcpeKu,111111 pa6orH111KOM (Hanp111Mep, n111w,e6n0Ka).

npasosotii noAXOA K 111MMyHonpocp111naKT11tKe npegycMarp111saer cnegyiow_ee:

•see rpa>KAaHe 06ecneY11tBalOTCH rocygapCTBOM B03MO>KHOCTblO nonyYll1Tb

32

10. nopSIAOK o6ecne~eHlllSI HaAJle>Ka~lllX

-

ycnoe111111 xpaHeH111S1,TpaHcnopT111poeK111, np111eMa

Ill y~eTa BaKU.lllH, aHaTOKClllHOB Ill annepreHa

Ty6epKyne3Horo

e YKpa111He.

10.106ll..\Lite no11o>KeH1r1S1

1.3TOT nopHAOK ycTaHaBJ1111BaeT Hagne>KaW,V1e YCJlOBltlfl XpaHeHV15l, TpaHcnopTV1pOBKll1, np111eMa 111 yYeTa BaKL.J,l/IH, aHaTOKCl/IHOB 111 annepreHa ry6epKyne3Horo, 1pe6yiow.111x oco6b1x TeMnepaTypHblX ycnos111LI! (ganee - «xonogosas:i u,enb» ).

2. 3ror nopHAOK pacnpocrpaHs:iercs:i Ha see saKL.J,\llHbl, aHaroKC\llHbl 111 annepreH Ty6epKyne3Hbliil, HY>KAaiow.111xG\ s co6niogeH111111 «xonogosoill u,en111», BB03111MblX ltlnl/1 np01113BOA111MblX B YKpa111He cy6beKTaMl/I X0351VlCTBOBaHl!151 He3aBl/ICl/IMO OT

o6ecneYv1Baiow,aR onn1MaJlbHb1111 TeMnepaTypHbll/I pe.>K111M xpaHeHl/IH 111 TpaHcnopT111posK111 Ha scex 3Tanax nepeMew,eH111ri saKL.J,lt1H, aHaTOKClllHOB 111 annepreHa 1y6epKyne3Horo OT npegnp111riTvrn-npo1113so,o.111TenH K no1pe6111Tenio.

3. Co6nio,o.eHl/le Hagne.>Kaw,111x ycnos111il1 xpaHeH111S1 111 TpaHcnopr111poBKl/I saKL.J,111H, aHaTOKCl/IHOB 111 annepreHa ry6epKyne3Horo s:isnHeTCS1 Heo6xo,o.111Mb1M 111 o6ri3arenbHblM ycnos111eM coxpaHeH111ri noKa3arenelll KaYecrsa (3cpcpeKTl/IBHocr111 111 6e3onacHOCT111), onpegeneHHblX 111 yTsep>t<geHHblX cepT111cp111KaTOM KaYecrsa, KOTOpblill npeAOCTaBn5leTCS1 npe,o.np111S1Tlt1eM - v13rOTOBv1TeneM. KOHTpOnb 3a co6rno,o.eH\11eM ycnOB\llVl «XOJl0,0.0BOil! u,en111» ocyw,ecTBJ15leTC5l B COOTBeTCTBlt1111 C 3Tlt1M nopHAKOM .IJ.enapraMeHTOM lt1MMYH061t1onor111YeCKll1X npenapaTOB 111 V1MMyHonpocp111naKTV1K1t1 rocygapcrseHHoro npe,o.np111ri1111S1 « rocyAapcTseHHblil1

V1 rpaHcnopT111poBaTbCH c co6niogeH1t1eM COOTBeTCTBYIOW,V1X TeMnepaTypHblX ycnos111111 «xono,o.oso111 u,en111», onpe,o.eneHHblX B 111HcrpyKL.J,ll15lX 06 111x npV1 MeHeH111 V1.

5. XpaHeH111e npenaparos np111 nosb1weHHoil1 reMnepaType np111so,o.111r K yMeHbW€HV1IO co,o.ep.>KaHlllH >Kll13Hecnoco6HblX M111Kp06HblX KJleTOK B .>Kl/IBblX 6aKrep111anbHblX 111 s111pycHblX saKu,111Hax.

3aMopa>t<111BaH111e cop6111posaHHblX npenaparos npV1BOAV1T K ,o,ecop6u,111111 aHTll11€HOB, YTO Bbl3b1BaeT 3HaYv1TenbHOe CHll1>KeH111e lt1X 111MMyHoreHHOCT111, HapyweH111e cpV13111Ko-x111M111YecKolll crpyKTYPbl 6enKos, na,o.eH111e aKT1t1BHOCT1t1 ,o,e111cTsyiow,ero sew.ecrsa.

33

I/I aHaTOKCl/IHOB, HO Ill K 803Hl/IKHOBeHl/llO HenpeABlllAeHHblX no60YHblX V1 Hecneu,111¢viLJecK111x npos:isneHvi~.

6.np111 onpeAefleHl/ll/I pe>Kl/IMa xpaHeHl/ls:l I/I TpaHCnOpTVlpOBKl/I BaKLJ,lllH, aHaTOKCl/IHOB V1 annepreHa Ty6epKyJle3HOro Heo6XOAlllMO pyKOBOACTBOBaTbCs:l l/IHCTPYKLJ,l/ls:IMl/I 06 I/IX np1t1MeHeHllll/I.

7.OnT111MaJlbHOilt Afls:I xpaHeH111s:i 111 TpaHcnopT111posK111 saKLJ,VlH, aHaTOKClllHOB 111

annepreHa Ty6epKyne3Horo s:isns:ieTcs:i TeMnepaTypa s npeAenax OT + 2 AO +8 o C.

XpaHeHllle nepopanbHOlll saKLJ,lllHbl Ans:i npo¢111naKTlllKlll non1110M111en111Ta peKOMeHAyeTCSl cornacHO lllHCTPYKLJJ.1111 0 ee np111MeHeHllll/I B 3aMopo>KeHHOM

COCTOs:IHl/ll/I nplll TeMneparype OT-15 AO -25 °( . np111 xpaHeHl/IVl V1 TpaHCnOpT111pOBKe

~ ~

saKLJ,l/IHbl B TeMnepaTypHOM pe>KlllMe OT+2 AO +8 ° c cpoK rOAHOCTl/I yKa3aHHOl/I saKLJ,lllHbl 6 Mecs:iu.es .

8. KaTerop1111.1ecKvi He AOnycKaeTcs:i 3aMopa>t<111BaH111e aAcop6111posaHHblX saKLJ,lllH, saKL.J,VlHbl npoTlllB renaTlllTa B, pacTsop111Tene~ Ans:i nvio¢vin1113viposaHHblX BaKLJ,lllH .

9.BaKLJ,l/IHbl AOJl>KHbl xpaHl/ITbCs:l B 3aw_viw_eHHOM OT CBeTa MecTe.

10.Jl1110¢111n1113111posaHHble BaKLJ,l/IHbl AOJl>KHbl lllCnOJlb30BaTbCSl BMeCTe c paCTBOplllTeneM OAHOro np01113BOAlllTeJls:i.

10.2CTpyKTypa «xo110Aoeoli1 u.en1.1»

1.0CHOBHblMll1 COCTaBnHIOLI.1-lllMl/I «XOflOAOBOVl u,en111» HBJlHeTCs:l HaJllllLJl/le: cneu,111anbHO noAroTosneHHoro nepcoHana, 06ecne1.1111sa10w_ero 06cny>Kv1BaH1t1e

xonOAl/lflbHOro o6opyAOBaHlll5l, xpaHeHl/ls:l I/I nocTaBKl/I BaKLJ,lllH, aHaTOKClllHOB Ill annepreHa Ty6epKyne3Horo s yYpe>KAeH111s:i 3ApasooxpaHeH111s:i YKpaviHb1;

XOilOAl/lnbHOro o6opyAOBaHvrn, TpaHcnopTHblX cpeACTB, 06ecneYl11Ba10w_111x HaAJle>Kaw_111e ycnOBV151 Ans:! xpaHeHllls:l V1 TpaHcnopTVlpOBKl/I BaKLJ,111H, aHaTOKCVlHOB 111 annepreHa Ty6epKyne3Horo;

nposeAeH111e KOHTpons:i 3a co6n10AeH111eM Heo6xoA111Moro TeMnepaTypHoro pe>t<111Ma Ha scex ero 3Tanax.

2. C111cTeMa «XOJlOAOBO~ u,en111» COCTOl/IT lll3 cneAYIOLI.1-VlX ypoBHe~:

1-~ - npeAnp111s:in1e-npo1113BOA11tTeJlb saKLJ,lllHbt, aHaT0Kc111Ha V1 annepreHa Ty6epKyne3Horo;

2-V! - CKJlaAbl onTosoro xpaHeH1115i saKLJ,lllH, aHaTOKClllHOB V1 annepreHa Ty6epKyne3Horo ( per1110Han bHble);

3-~ - pa~oHHble 111 ropoACK111e y1.1pe>K,O,eH111s:l 3ApasooxpaHeHl/ls:i (Tepp - 111Top111anbHb1e);

4-~ - Ka6111HeTbl nplllBl/IBOK JleLJe6Ho-npo¢111naKTlllYeCKlllX yype>K,D,eHlllV! (yYaCTKOBble 6onbHlllU,bl, aM6ynaTopV1111, AeTcK111e non111Kn111H1t1KV1, poAlllJ1bHb1e AOMa 111 T.,IJ,.) .

3. Ha scex yposHs:ix «xono,o,oso111 u,en111» o6s:i3aTenbHO nposo,IJ,111Tcs:1

34

per111crpau,111f1 s )f(ypHanax yyera nonyLJeHltlfl, ycnos111111 xpaHeHltlfl 111 AanbHe111wero nepeMew,eHvrn saKU,ll1H, aHaTOKCll1HOB 111 annepreHa ry6epKyne3Horo norpe6111remo c o6f:i3arenbHoiit per111crpau,111eiit saKU,ll1Hbl, aHaTOKC1t1Ha 111 annepreHa ry6epKyne3Horo no roprosoMy Ha3BaH111t0, KOnll1YeCTBY A03, HOMepy cep111111, cpoKy rOAHOCTVl, AaTe nonyYeHVIH, ycnOBVlflM xpaHeHltlfl ll1 rpaHcnopr1t1pOBKll1, noKa3aTeJlHM KapT-VIHA111KaTopoB, 1t1HA1t1Karopos 3aMopa)f(1t1BaH1t1fl 111 noKa3arenriM per111crp111py10w,111x np1116opos (repMopeecrparopbl, repMorecrepb1) c yKa3aHvieM cpaM11111111vi orsercrseHHoro nviu,a.

noKa3arenvi repMorecrepos, repMopeeaparopos 111 repMorpacpos s BlllAe

reMneparypHblX rpacp111Kos 111 ra611111u, xpaHflT BMecre c )f(ypHanoM per111apau,111111

- -

TeMneparypbl AnH AanbHeviwe111 OTYeTHOCTVl.

4. Ha scex ypoBHflX «xonoAosoiit u,envi» AOn>t<Hbl pa6orarb Ha3HaYeHHble pyKoBOAlllTeneM yYpe>t<AeHVlfl cneu,111a11111crb1 c YeTKO onpeAeneHHb1Mll1 AOJl>KHOCTHblMlll o6~!3aHHOCHlMV1 B COOTBeTCTBll1VI c 3aHl/IMaeMoiit AOJl)f(HOCTblO.

B cvicreMe «xonoAOBoiit u,en111» 111cnonb3YIOT cneAy10w,ee 06opyA0BaH111e: xonOAV1nbHb1e KOMHaTbl (KaMepb1 ), Mopo3111nbHb1e KaMepb1, Mopo3111nbHll1Kll1, 6blTOBble xonOA111JlbHll1KV1, repMOKOHTeV1Hepbl, MeAll1U,ll1HCKll1e cyMKV1xonoAV1nbHll1Kll1, xnaA03neMeHTbl, repMOll1HAV1Karopb1, repMoper111crparopb1, repM0MeTpb1, repMorpacpb1 111 repMorecrepb1.

10.306opyAOBaH"'1e«XOllOAOBOmA 1..1,en1.1»

1.XonOAVlnbHble KOMHaTbl ( KaMepbl) ll1Cnonb3YIOTCH ,[l,nfl xpaHeHltlfl Ill ynaKOBKlll BaKU,lllH, aHaTOKCVIHOB VI annepreHa ry6epKyne3HOro. 3arpy3Ka XOJlOAll1JlbHOiit KOMHaTbl AOn)f(HO o6ecneYv1BaTb cso60AHYIO U,ll1PKYJlflU,V1IO B03Ayxa no BCeMy o6beMy KOMHaTbl (KaMepbl) .

2.Mop03ll1nbHble KaMepbl 111cnonb3YIOT Ans:! BaKU,ll1H, xpaHeHV'le KOTOpbl X cornaCHO ll1HCTpyKU,Vlll1 no np111MeHeHl!llO AOJl>KHO npOll1CXOAll1Tb B3aMopo>t<eHHOM COCTOHHll1ll1, a TaK>t<e AJlH 3aMopa>t<l/1BaHll15l ll1 xpaHeHvrn xnaA03neMeHTOM .

3.Mopo3111nbHll1KV1 111cno11b3YIOT Anfl 3aMopa>KvrnaHVIH xna,[],o3neMeHTOB.

4. obJTOBble XOJlOA1111lbHlllKlll 111cnonb3YIOT AilH xpaHeHlllfl saKU,ll1H, aHaTOKCll1HOB

viannepreHa ry6epKyne3Horo Ha 3-M 111 4-M ypoBHflX «xonoAosoiit u,en111» .

5.TepMOKOHTeiitHep - eMKOCTb pa311w-1HblX pa3Mepos Vl3 repM01113on111py10w,ero Marep111ana, repMeTlllYHO 3aKpb1saercs:i KpblWKoiit. TepMOKOHTeiitHepb1 eMKOCTblO

csb1we 10 AMi AOJ1>t<Hbl o6ecneYv1BaTb reMneparypHbiilt pe>t<111M xpaHeHvrn 111 rpaHcnopr111pOBKll1 OT + 2 AO +8 ° c He MeHee 48 Yacos np1t1 noCTOflHHOM

- 30°C. TepMOKOHTeillHepbl eMKOCTblO MeHee 10 AMi AOJl>KHbl 06ecneY111saTb TeMneparypHblll1 pe>t<ll1M xpaHeHltlfl ll1 rpaHcnopr111pOBKV1 BaKU,111H, aHaTOKClllHOB 111 annepreHa ry6epKyne3Horo or + 2 AO +8 ° C He MeHee 24 11acos np111 nOCTOflHHOM B03AeiitCTBll1111 TeMneparypbl OKpy>t<a10w,eiit cpe,[],bl +43 ° c 111 OT +8 AO + 2 ° c He MeHee 10 LJaCOB np111 nOCTOs:lHHOM B03AeC1cTBll1111 TeMneparypbl 0Kpy)f(a10w,ei/1 cpeAbl 20 ° C.

35

6. MeA111W111HCKa~ cyMKa-xonOAll111bH111K AOJl)KHa 06ecneY111BaTb reMneparypHbliil pe)KlllM or +2 AO +8 ° C. BHyrpeHHHH nosepxHoCTb cyMKlll AOJl)KHa 6b1Tb noKpblTa Marep1t1a110M, n0380Jls:!IOW,V1M npOBOAlllTb Ae3111HcpeKWllllO.

7. XJlaA03JleMeHT - eMKOCTb c repMeT1t1YeCKlll 3aKpblTOiil npo6Koiil, KOTOpas:! 3anOJlHf!eTCfl BOAOiil 111Jllt1 cnew1t1aJlbHOiil )Kl!IAKOCTblO. )lnfl rpaHcnopTV1pOBKV1 saKU,111H, aHaTOKCll1HOB 111 annepreHa ry6epKyne3Horo s reYeHvi111 1 Yaca xnaA03neMeHT npe,o,sap111re11bHO B re1..1eH111e He MeHee 1-3-x Yacos xpaH111rcs:1 B XOJ10AV1JlbHll1Ke (TeMneparypa XJlaA03JleMeHTa AOJl>KHa COCTaBJlHTb OT +2 ,o,o +8°C). Ec11111 speMfl rpaHcnopr1t1posK1t1 saKu,1t1H, aHaroKCV1HOB 111 annepreHa

ry6epKyne3Horo B repMOKOHTeiilHepbl Allf! rpaHcnopr111posK111 x11a,o,0311eM~HT KOHA111U.111PYIOT. JJ,nf! npe,o,orspaw,eHVlf! npHMOro KOHTaKTa saKU,lllH, aHaTOKCll1HOB 111 a.nnepreHa ry6epKyne3Horo c xnaA0311eMeHTaM111 Me>KAY HlllMlll pa3Mew,aercri repM01113011111py10w,111iil MaTep111a11 (B03AYWHble naKeTbl, KaproH, neHonnacr). 0nTlllM3JlbHaf! TeMnepaTypa TpaHcnopT111pOBKll1 BaKWV1H, aHaTOKCll1HOB 111 annepreHa Ty6epKyne3Horo OT + 2 AO +8 ° C.

np111 onpeAeJleH1t1111 oco6eHHOCTeiil Ka>K.o.oiil saKU,111Hbl, aHaT0Kc111Ha 111 annepreHa ry6epKyne3Horo Heo6xo,o,111Mo YYlllTblBaTb rpe6osaH111f! 111HcrpyKw111iil 06 111x

np111MeHeH111111.

8. TepMOVIHAl!IKaropb1:

8.1.KoHTpOilbHaf! KaproYKa -111H,D,111Karop (,o,anee - KaproYKa-111HAll1KaTop) - 3TO BpeMeHHOil! 111HTerparop TeMneparypbl, npVIMeHf!eMoro ,D,Jlfl MOHll1TOpV1Hra reMneparypbl 111 cp111Kcau,111111reMnepaTypHoro B03,D,eiilcrs111f! Ha npenapar. KapTOLfKalllHA111Karop VIMeeT YeTblpe repMOYYBCTBll1TeJlbHblX OKOWKa-111HAlllKaTopa (A, B, C, D), Mecro AllH 3an111c111 111HcpopMau,111111 o saKu,111He, aHaTOKCl!IHe 111 annepreHe

Ty6epKy.ne3HOM - roprosoro Ha3BaHl!lf!, Ha111MeHosaH111H npeAnp111sn111s:t- 1113roros111re11f!, AaTbl ornpas11eH111s:t, AaTbl no11yYeH111s:1 111 Bb1AaY111 npenapara, Ha111MeH0BaH111f! yYpe>KAeH111s:1 3ApasooxpaHeHvrn, noKa3are11e111 OKoweKlllHAlllKaropos. 0KOWKll1 nocreneHHO pear111py10T Ha nosb1WeH111e reMneparypbl, MeHf!f! U,BeT c 6enoro Ha Cll1Hll1ill . KapTOYKa-111HA111Karop COAep>KlllT l/IHCTPYKU,11110 06 111cnOJlb30BaH111111 111 ra611V1u,y, o6b5KHf!eT noKa3are11111 0KoweK-ll1HAV1Karopos.

8 .2. V1HA111Karop 3aMopa>K111saH11rn (Aanee lllHAll1Karop) cpeACTBO KOHTpOllf!, KOTOpblill np111MeHS1eTCS1 ,D,Jlf! KOHTp0115l 3a TeMnepaTypHblM pe>Kll1MOM

Kancyny c Kpacf!W,lllM pacrsopoM, Koropb1iil pa3pywaeTcs:1, ec11111 6011bwe Yaca reMnepaTypa cocras.nf!na 0 ° C.

8.3. 311eKTpoHHb1Lll lllHA111KaTop 3aMopa>Kv1BaH111~ « Freez - teg», KOTOpb1iil KOHTpon111pyer TeMnepaTypy 0Kpy>Ka10w,e111 cpeAbl 111 noKa3blBaer Ha ,o,111cnnee cpaKT B03,D,et71CTBLll~ TeMneparypbl Hll1>Ke 0 ° c B TeYeH111e 10 Mll1HyT.

TepMoper111crparopb1 06ecneY111sa10r KOHTponb reMneparypHoro pe>K111Ma Ha scex ypOBH~X «XOJlOAOBOvt u,en111» np111 xpaHeHll1111 Ill rpaHcnopr111pOBKe B3KU,111H,

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aHaTOKClllHOB 111 annepreHa ry6epKyne3Horo.

9. TepMorpacp - np1116op AnH HenpepblBHotit per111apau,111111 reMneparypb1 B xonOA111nbHOM o6opyAOBaHllllll.

10.TepMOMeTpbl 111cnOflb3YIOT AflH KOHTpons:i TeMneparypHoro pe>K111Ma np111 xpaHeH111111 saKU,lllH, aHaTOKG1HOB 111 annepreHa ry6epKyne3Horo. TepMOMeTpb1 AOJl>KHbl 6b1Tb cepr111cp111u,111posaHbl 111 nosepeHHb1e.

11.TepMorecrep - 3neKrpoHHOe ycrpotitcrso MHoroKparHoro np111MeHeH111s:i Ans:i He3aBV1ClllMOro KOHTponH TeMneparypbl c 803MO>KHOCTblO AOKyMeHTlllpOBaHll\s:l

nonyYeHHbtX AaHHblX s 311eKrpoHHOM, 6yMa>KHOM 11111111 1t1HOM BVlAe. Pa60Y111tll AV1ana3oH reMneparyp OT - 30 ° AO +50 ° C V1 speMeHHoilt AV1CKpeTHOCTblO npoBeAeHV15l V13MepeHV1tit TeMneparypbl - OT 1 AO 60 MV1HYT B 3aBlllCV1MOCH1 OT

ronbKO repM0Tecrepb1, npoweAWllle nosepKy s coorseTcrs111111 c rpe6osaH111s:iM111 Ae111crsy10w,ero 3aKOHOAarenbCTsa.

11. Tpe6oeaHvu1 K xpaHeHL11t0 eaKU."1H, aHaTOKC"1HOB "1 annepreHa Ty6epKyne3Horo

1. np111 xpaHeH111V1 aaKU,111H, aHaTOKCV1HOB 111 annepreHa ry6epKyne3Horo Heo6XOAV1MO np111Aep>K1t1BaTbCH cneAylOW,VlX 06w,111x npaa111n:

saKU,lllHbl, aHaTOKCll1Hbl 111 annepreH ry6epKyne3Hbttit xpaHs:iT np111 reMneparype, yKa3aHHOtit B lt1HCTPYKU.111s:!X 06 VIX nplllMeHeH111111;

pacrsop111re11111 Ans:i saKLJ,lllH Heo6XOAV1MO xpaHlllTb np111 reMneparype or +2 AO +8 ° C c u.enblO npeAorapaw,eHlllH noab1weH111H reMneparypb1 saKLJ,lllHbl np111 ee paCTBOpeHV1111;

BaKLJ,lllHbl, KOTOpble Tpe6ylOT xpaHeHlllH B 3aMopo>KeHHOM COCTOs:!Hlllll1, AOn>K- Hbl xpaHll1TbCs:l B MOp03V1flbHblX KaMepax npV1 TeMneparype OT -15 AO -25 ° c AJrn 1-2-ro ypOBHei/i CVlCTeMbl "xonOAOBOtit u,en111";

saKU,111Hbl, aHaTOKCll1Hbl V1 annepreH ry6epKyne3Hbttit AOfl>KHbl 6b1Tb pa3Mew,e- Hbl TaKll1M o6pa30M, YT06bl K Ka>KAOVl ynaKOBKe 6blfl AOCTyn oxna>KAeHHOro B03Ayxa;

aaKU,l/IHbl, aHaToKCV1Hbl 111 annepreH ry6epKyne3Hbttit AOfl>KHbl 6btTb pa3Mew,e- Hbl TaKVlM o6pa30M, YT06bl npenapaT, KOTOpbttit VlMeeT MeHbWVlill cpoK rOAHOCTlll, 111cnonb3osancs:i s nepsy10 oYepeAb.

2. ,LJ.nri xpaHeHl/151 saKLJ,111H, aHaTOKCV1HOB 111 annepreHa ry6epKyne3Horo 111cnonb3YIOT MOp03111JlbHble Ill XOJlOAlllflbHble KaMepbl, XOflOA111flbHble WKacpbl.

3. 06w,111tit o6beM XOflOAV1flbHOro o6opyAOBaHll1s:I 1-ro ypOBHs:I Cll1CTeMbl "xonOAOBOVt u,en111" 3aBlllClllT OT KOflW-leCTBa BaKL.J,lllH, aHaTOKCll1HOB Ill annepreHa ry6epKyne3Horo. BaKU,VlHbl, aHaTOKCV1Hbl 111 annepreH Ty6epKyne3Hbtill xpaHs:iT

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cornacHO V1HCTPYKU.VHlM 0 VlX npV1MeHeHV1s:l B xonOAvtnbHblX V1nV1 MOp03V1nbHblX KaMepax. YnaKOBKY BaKLJ,111H, aHaTOKCll1HOB 111 annepreHa Ty6epKyne3Horo B repMOKOHTell1Hepb1 AnSi rpaHcnopT111pOBKV1 ocyw,ecrBnHIOT B xonOAV1JlbHblX KOM HaTaX (Ka Mepax).

4. XonOAV1JlbHoe 06opyA0BaH111e, npeAHa3HaYeHHoe AJ15i xpaHeHvrn BaKL.J,lllH, aHaTOKCVlHOB Ill annepreHa ry6epKyne3HOro, AOH>KHO VlCnOJlb30BaTbC5i TOJlbKO no Ha3HaYeHVllO. (OBMeCTHOe xpaHeHVle BaKL.J,VlH, aHaTOKCVlHOB Ill annepreHa ry6epKyne3Horo c Apyr111MV1 ne1<apcrseHHblMV1 cpeACTBaM111 V1 nocTopOHHV1Mlll Marep111anaM111, a TaK>Ke xpaHeH111e saKL.J,lllH, aHaroKCV1HOB 111 annepreHa Ty6epKyne3Horo B ABepSiX XOJ10AV1JlbHV1KOB He)J.onyCTV1MO.

5. ,[J,nri nocneAy10w,111x yposHeill "xonoAosoill u.enll1" (2-4-ill ypoBHVl c111creMbl "xonOAOBOLll u,en1r1") o6w,ll1Lll o6beM XOJlOAlllJlbHOro o6opyAOBaHll15i AOJl>KeH 06ecneY111sarb HaAne>Kaw,ee xpaHeHllle scero Konw~ecTBa saKU,lllH, aHaToKcCiHOB ll1 annepreHa ry6epKyne3Horo, HaXOASiW,VlXCH Ha AaHHOM yposHe. PacLJeT o6beMa xpaHeHV1H npOBOASiT no noKa3aTeJ15iM COOTHOWeHlllSi reoMeTp111V1 ynaKOBKl/I npenapara (o6beM ynaKOBKVl B CM3 ) K o6w,eMy o6beMy XOJlOA111JlbHOro

12. Tpe6oeaH111S1 K TpaHcnopT111poeKe eaKU.111H, aHaTOKCll1HOB 111 annepreHa Ty6epKyne3Horo

1. TpaHcnopr111pos1<a sa1<u,1t1H, aHaro1<c1t1HOB 111 annepreHa ry6epKyne3Horo AOJl>KHa ocyw.ecTBJls:!TbCSi B repMOKOHTe1t1Hepax c COOTBeTCTBYIOW,lllMV1 Kapra- Ml/l-lllHAV1KaropaMV1, vtHAlllKaropaMvt 3aMopa>Kll1BaHlllH 111 repMorecrepoM pecpp111>KeparopHblM rpaHcnoproM np111 reMneparype or + 2 AO +8° C.

2. 3arpy3Ka npenapaTOB B repMOKOHTeillHepbl ocyw,eCTBJ15i€TC5i B XOJlOAlllJlb - HOill KaMepe (noMew,eH111111 AJlH xpaHeHvrn saKU,lllH, aHaroKCvtHOB 111 annepreHa ry6epKyne3Horo) . 8 VlCKJllOYvnenbHblX cnyYaflx 3arpy31<a MO>Ker ocyw,ecrsn~nb­ CSi np111 reMneparype B cpoK, He npesb1waiow,111ill 10 M111Hyr.

XnaA03JleMeHTbl KOHAV1U.111PYIOT AO nOf!BneHvt5i B Hll1X >Kll1AKOCTll1 Ill cao6op,- HOro nepeMeW,eHl/151 JlbAa BHyTplll . B r epMOKOHTeillHepe AOJl>KHbl 6b1Tb cpeACTBa KOHTpons:i 3a TeMneparypHblM pe>KV1MOM .

3.TepMOKOHTeLllHepb1, Koropb1e npeAHa3HaYeHbl AJ15i rpaHcnopn-1poBKll1 sa1<- u,111H, aHaro1<c111Hos 111 annepreHa ry6epKyne3Horo, AOJl>KHbl 6b1Tb 111cnpasHb1 111 Moryr 111CnOJlb30BaTbC5i MHOroKpaTHO.

4.npeAnpV15iTll1€-vt3rOTOBV1Tenb V1 CKJlaAbl OnTOBOrO xpaHeHvtA BaKU,lllH, aHaTOKClllHOB Ill annepreHa Ty6epKyne3HOro AOJl>KHbl vtMeTb AOCTaTOYHOe KOn111-

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