- •Cardiotocography
- •Ultrasound examination
- •Self control questions.
- •3.5.2. Self control tests.
- •Gestosis
- •Oligoamnios
- •Anemia
- •Hydramnion
- •1. Recognize factors which determine drug passage across the placenta and into breast milk.
- •2. Identify aspects of medications that determine safety during lactation.
- •• A substance, organism, physical agents or deficiency state capable of inducing abnormal structure or function such as:
- •• Timing of exposure
- •• Developmental stage during exposure
- •• Maternal dose and duration
- •• Maternal pharmacokinetics
- •IV. FDA Pregnancy Categories
- •V. FDA Pregnancy Categories
- •VI. FDA Labeling Changes
- •VII. Drug Transfer to the Fetus
- •VIII. Drug Passage into Breast Milk
- •IX. Drug Transfer
- •XI. Fetal Drug Disposition
- •• 60 – 80% passes through liver, the rest travels through ductus venosus to heart and brain
- •XII. Drug Concentration in Breast Milk
- •XIII. Calculating Drug Exposure
- •Infant dose/maternal dose using mg/kg/d
- •XIV. Neonatal Factors
- •XV. Infant Adverse Effects
- •XVI. Anti-infectives
- •XVII. Penicillins
- •XVIII. Cephalosporins
- •• Category B/C/B in pregnancy
- •XXIII. Sulfonamides
- •XXV. Miscellaneous Antibiotics
- •XXVI. Miscellaneous Antibiotics
- •XXVII. Miscellaneous Antibiotics
- •XXVIII. Miscellaneous Antibiotics
- •Antiretrovirals/NNRTI (delavirdine, efavirenz, nevirapine)
- •Antiretrovirals/PI
- •Antiretrovirals/Fusion Inhibitor (enfuvirtide)
- •Antiretroviral Combinations
- •Antifungals/Echinocandins (anidulofungin, caspofungin, micafungin)
- •Antifungals/Polyenes
- •XXXII. Migraine Headache Therapy
- •Triptans (5-HT1 agonists)
- •Triptans (5-HT1 agonists)
- •Butalbital and Caffeine
- •Dichloralphenazone and Isometheptene (Midrin)
- •Questions to Ask:
- •Questions to Ask:
- •Considerations in Breastfeeding:
- •• Withhold or delay therapy if possible
Labors first, urgent, premature rupture of fetal membranes. Primary delicacy of patrimonial activity, labors with stimulation by a solution of Oxytocinum (5 ME). The fetus male was born, without respiration, palpitation - 20 impacts in one minute, tones deaf, the physiological reflexes are not caused. A skin acyanotic, muscles tonus flaccid.
1.Estimate a newborn state on a Apgar scale.
2.Name the stages of reanimation measures.
3.Carry out reanimation measures on a dummy.
Task № 2.
The parturient woman A., labors first, urgent, proceed 16 hours. Contractions 45 sec every 3-4 min. Light amniotic waters expulsed. A position of a fetus longitudinal, presenting part - head, small segment in an entrance in a small pelvis. The palpitation of a fetus muffled, 90 impacts in one minute, between contractions is not restored.
Vaginal inspection: opening of uterine cervix - 7-8 cm.
1.Estimate an obstetrical situation and intrauterine fetal condition.
2.Make the plan of the further conducting of labors.
Task № 3.
Primagravida woman 24 years old, suffer by inherent defect of heart.
Duration of the I first period of labors - 8 hours. At an auscultation of palpitation of a fetus - wrong rhythm, tachycardia up to 160 impacts an one minute, or bradycardia up to 90 impacts in 1 minute. Cardiac tones deaf, or clear.
Movement of a fetus often, strong. In amniotic waters - Meconium.
1.Your diagnosis.
2.Medical measures.
Self control questions.
2. Definition of concepts: "fetus hypoxia", "newborn asphyxia", "newborn depression".
2.The reasons of fetus hypoxia.
3.A pathogeny of fetus hypoxia.
4.What is a "vena cava inferior prelum" syndrome?
5.A symptomatology of fetus hypoxia.
6.What methods it is possible to establish a fetus hypoxia presence by?
7.Prove and list measures on fetus hypoxia treatment.
8.How it is necessary to carry out an Oxygen inhalation to the parturient woman?
9.What is the difference between the modern complex of fetus hypoxia
treatment and " Nikolaev’s triad"?
10.Why presently have refused such preparations as Cordiaminum, Corazolum, Lobeline at hypoxic states?
11.How and when the estimation of a newborn state on a Apgar scale is carried out?
12.When it is necessary to begin a slime suction from the top respiratory ways?