- •Series Editor Foreword
- •Preface
- •Contents
- •Contributors
- •Differential Diagnosis
- •Evaluation
- •Treatment
- •Discussion
- •References
- •Background
- •Normal Pubertal Stages
- •Differential Diagnosis of Precocious Puberty
- •Evaluation [1, 3, 4]
- •Treatment [1, 2]
- •Discussion
- •References
- •Background
- •Differential Diagnosis of Delayed Puberty
- •Evaluation
- •History and Physical Examination
- •Laboratory Investigation and Imaging
- •Treatment
- •Discussion
- •Suggested Readings
- •Discussion
- •Differential Diagnosis
- •References
- •Discussion
- •References
- •Differential Diagnosis
- •Evaluation
- •Treatment
- •Discussion
- •References
- •Discussion
- •References
- •Discussion
- •References
- •Discussion
- •References
- •Discussion
- •References
- •Discussion
- •References
- •Discussion
- •Interpretation of Thyroid Function Tests (TFTs)
- •Iodine Supplementation for Pregnancy and Lactation
- •Screening for Maternal Hypothyroidism
- •Maternal Subclinical Hypothyroidism
- •Thyroid Autoimmunity
- •Maternal Hyperthyroidism: Diagnosis
- •Maternal Hyperthyroidism: Treatment
- •Postpartum Thyroiditis
- •Summary
- •References
- •Discussion
- •References
- •Discussion
- •References
- •Discussion
- •References
- •Discussion
- •References
- •Discussion
- •References
- •Discussion
- •References
- •Discussion
- •References
- •Discussion
- •References
- •Discussion
- •Intrauterine Pathology
- •Thin Lining
- •Endometrial Receptivity Analysis (ERA)
- •Chronic Endometritis
- •Conclusion
- •References
- •Discussion
- •References
- •Discussion
- •History
- •Physical Exam
- •Semen Analysis
- •Laboratory Testing
- •Genetic Testing
- •Adjunctive Tests
- •Imaging
- •References
- •Discussion
- •Pathophysiology
- •Evaluation
- •Treatment
- •Lifestyle Changes
- •Medications
- •Phosphodiesterase 5 Inhibitors
- •Vacuum Erection Device
- •Intraurethral Alprostadil
- •Intracavernosal Injections
- •Surgery
- •References
- •Discussion
- •History
- •Semen Analysis
- •Physical Examination
- •Proper Varicocele Examination
- •Laboratory Investigations
- •Additional Investigations for the Pain Include
- •Other Investigations for Infertility in the Context of Varicoceles
- •Treatment
- •Indications for Varicocele Treatment Include the Following
- •Numerous Treatments for Varicocele Exist
- •References
- •Discussion
- •Semen Analysis
- •History and Physical Examination
- •Laboratory Investigations
- •Testicular Biopsy
- •Treatment
- •Surgical Techniques for Sperm Retrieval [13]
- •Fresh Vs. Frozen Sperm
- •Counseling
- •References
- •Discussion
- •References
- •Discussion
- •References
- •Discussion
- •References
- •Background
- •Epidemiology
- •Evaluation
- •Treatment
- •Non-ART Treatment
- •Accelerated Utilization of ART
- •ART Success Rates
- •Recent Trends in ART
- •Discussion
- •Conclusion
- •Suggested Readings
- •Evaluation
- •Differential Diagnosis
- •Discussion
- •References
- •Discussion
- •References
- •Discussion
- •References
- •Discussion
- •Suggested Readings
- •Diagnosis
- •Management
- •Discussion
- •References
- •Index
25 Varicocele |
167 |
Semen Analysis
Patients with suspected infertility should have an appropriately collected semen analysis and then have it repeated. The sample should be obtained with self- stimulation, abstinence period of 2–5 days, and no lubrication. Two samples should be obtained at least 4 weeks apart. Samples should be examined with microscopic examination by a skilled technician (Table 25.1). Critical components of the semen analysis include:
Physical Examination
A physical examination for patients with pain and infertility is very helpful for diagnosis. This should include a general examination, as well as focused exam on the genitourinary organs [2]:
•\ General appearance (congenital abnormalities, secondary sex characteristics) •\ Body habitus and gynecomastia
•\ Abdomen and inguinal areas for scars
•\ Phallic examination (circumcision status, meatal opening) •\ Examination of the vas deferens (unilateral or bilateral) •\ Testicular examination (size and consistency)
•\ Epididymal examination (dilated or fat)
•\ Cord examination (varicoceles, including grade or hernias) •\ Digital rectal examination
Table 25.1 WHO 2010 semen parameters [4]
|
World Health Organization |
|
Semen parameter |
2010 values |
Abnormality |
Volume (mL) |
1.5–6 |
|
Total sperm count (TSC) |
39 |
Azoospermia (TSC = 0) |
(million) |
|
Severe Oligospermia |
Concentration (million/mL) |
15 |
(TSC<5 millions) |
|
|
Oligospermia (TSC<15 millions) |
Progressive motility (%) |
32 |
Asthenospermia |
|
|
|
Total motility (%) |
40 |
|
Normal morphology (%) |
4–14% |
Teratozoospermia |
(strict) |
|
|
|
|
|
Vitality (%) |
58 |
|
Leukocyte count (million/ |
<1.0 |
|
mL) |
|
|
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168 |
N. Punjani and M. Goldstein |
|
Proper Varicocele Examination |
|
|
•\ |
Patient should be in a quiet room and heating pad placed on the scrotum (both a |
|
|
cold room and anxiety may make examination challenging) |
|
•\ |
Examination needs to be completed both supine and standing |
|
•\ |
Testicular size should be estimated with an orchidometer |
|
•\ |
After visualization for grossly dilated veins, the scrotum should be squeezed |
|
|
between ngers above the testicle in the area of the cord. This should be repeated |
|
|
with Valsalva |
|
•\ |
Any veins should be palpated and felt as patient changes from standing to supine; |
|
|
abnormal veins will collapse and normal veins will stay palpable |
|
•\ |
The exam should be repeated while supine |
|
•\ |
Grading (modi ed from Dubin and Amelar) |
|
–– Grade 1—palpable impulse with Valsalva maneuver
–– Grade 2—palpable impulse with Valsalva maneuver and palpable tortuosity of cord veins
–– Grade 3—visible impulse on Valsalva and when upright without Valsalva
Grade 3a—just visible
Grade 3b— lls most of the hemiscrotum
Grade 3c— lls entire scrotum (Fig 25.1).
Fig. 25.1 Diagram illustrating a grade 3 varicocele