- •Contributors of Campbell-Walsh-Wein, 12th Edition
- •Patient history and physical examination
- •Clinic visit set-up
- •Patient history
- •Chief complaint (CC)
- •History of present illness (HPI)
- •Constitutional symptoms.
- •Pain.
- •Hematuria.
- •Lower urinary tract symptoms (LUTS).
- •Urinary incontinence
- •Erectile dysfunction (ED).
- •Other urologic conditions.
- •Past medical/surgical history
- •Performance status
- •Medications
- •Social history
- •Family history
- •Review of systems
- •Physical examination
- •Vital signs
- •General appearance
- •Kidneys
- •Bladder
- •Penis
- •Scrotum and contents
- •Digital rectal examination (DRE)
- •Pelvic examination in the female
- •Laboratory tests
- •Urinalysis
- •UA evaluation
- •Specific gravity and osmolality.
- •Blood/hematuria.
- •Leukocyte esterase (LE) and nitrite.
- •Bacteria.
- •Yeast.
- •Urine cytology
- •Serum studies
- •Creatinine and glomerular filtration rate (GFR)
- •Prostate-specific antigen (PSA)
- •Alpha-fetoprotein (AFP), human chorionic gonadotropin (HCG), and lactate dehydrogenase (LDH)
- •Endocrinologic studies
- •Parathyroid hormone
- •Office diagnostic procedures
- •Uroflowmetry
- •Post void residual (PVR)
- •Cystometography and urodynamic studies
- •Cystourethroscopy
- •Imaging of the urinary tract
- •Plain abdominal radiography.
- •Retrograde pyelogram (RPG).
- •Loopography.
- •Retrograde urethrography.
- •Voiding cystourethrogram (VCUG).
- •Functional imaging with nuclear scintigraphy
- •Technetium 99m –diethylenetriamine pentaacetic acid (99m TC-DTPA)
- •Technetium 99m –dimercaptosuccinic acid (99m TC-DMSA)
- •Technetium 99m -mercaptoacetyltriglycine (99m TC-MAG3)
- •Diuretic scintigraphy
- •Phamacokinetics.
- •Phases of dynamic renal imaging.
- •Urologic ultrasonography
- •Renal ultrasonography.
- •Bladder ultrasonography.
- •Scrotal ultrasonography.
- •Ultrasonography of the penis and male urethra.
- •Transperineal/translabial ultrasound.
- •Transrectal ultrasonography of the prostate (TRUS).
- •Urologic computed tomography (CT)
- •Types of CT.
- •Urolithiasis.
- •Cystic and solid renal masses.
- •Urologic magnetic resonance imaging (MRI)
- •Adrenal MRI.
- •Renal MRI.
- •Urothelial cell carcinoma (upper and lower tract).
- •Prostate MRI.
- •Nuclear medicine in urology
- •Positron emission tomography (PET).
- •Hematuria
- •Causes of microscopic hematuria
- •Selecting patients for evaluation
- •Lower tract evaluation
- •Upper tract evaluation
- •Suggested readings
CHAPTER 1 Evaluation of the Urologic Patient 51
Key Points
•A urologist should systematically perform a complete urologic history and physical exam considering a broad differential for the presenting chief complaint.
•Itisimportanttoconsiderallcomponentsofapatient’sstatusincluding social history and performance status as well as special considerations for certain populations including children and the elderly.
•A dipstick urine test alone is inadequate for the diagnosis of microscopic hematuria. AMH must be demonstrated by 3 RBC/ HPF on microscopic examination.
•Urine cytology is not recommended during initial workup for
AMH, however it is specific for high-grade UCC.
•A CT urogram is sensitive and specific for upper tract urothelial cell carcinoma and is a study used during workup of hematuria.
•A CT noncontrast study of the abdomen and pelvis is key for evaluating urolithiasis with the exception of indinavir stones.
•For a renal mass on MRI, the most important characteristic indicating malignancy is enhancement.
Molecular imaging for urologic malignancies is most often performed using the PET radiotracer 2-deoxy-2-[18 F]fluoro-D-glucose (18 F-FDG).
Suggested Readings
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Barry MJ, Fowler FJ, O’Leary MP, et al. The American urological association symptom index for benign prostatic hyperplasia. J Urol 1992;148:1549.
Davis R, Jones JS, Barocas DA, et al. Diagnosis, evaluation and follow-up of asymptomatic microhematuria (AMH) in adults: AUA guideline. J Urol 2012;188: 2473-2481.
Farwell MD, Pryma DA, Mankoff DA. PET/CT imaging in cancer: current applications and future directions. Cancer 2014;120:3433-3445.
Karnofsky DA, Abelmann WH, Craver LF, et al. The use of the nitrogen mustards in the palliative treatment of carcinoma—with particular reference to bronchogenic carcinoma. Cancer, 1948;1(4):634-656.
Kriston L, Gunzler C, Harms A, et al. Confirmatory factor analysis of the German version of the international index of erectile function (IIEF): a comparison of four models. J Sex Med 2008;5:92.
52 CHAPTER 1 Evaluation of the Urologic Patient
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