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CHAPTER 1  Evaluation of the Urologic Patient 51

Key Points

A urologist should systematically perform a complete urologic history and physical exam considering a broad differential for the presenting chief complaint.

Itisimportanttoconsiderallcomponentsofapatient’sstatusincluding social history and performance status as well as special considerations for certain populations including children and the elderly.

A dipstick urine test alone is inadequate for the diagnosis of microscopic hematuria. AMH must be demonstrated by 3 RBC/ HPF on microscopic examination.

Urine cytology is not recommended during initial workup for

AMH, however it is specific for high-grade UCC.

A CT urogram is sensitive and specific for upper tract urothelial cell carcinoma and is a study used during workup of hematuria.

A CT noncontrast study of the abdomen and pelvis is key for evaluating urolithiasis with the exception of indinavir stones.

For a renal mass on MRI, the most important characteristic indicating malignancy is enhancement.

Molecular imaging for urologic malignancies is most often performed using the PET radiotracer 2-deoxy-2-[18 F]fluoro-D-glucose (18 F-FDG).

Suggested Readings

American College of Radiology (ACR). Manual on contrast media. 2020. https://www. acr.org/-/media/ACR/Files/Clinical-Resources/Contrast_Media.pdf.

Barocas DA, Boorjian SA, Alvarez RD, et al. Microhematuria: AUA/SUFU Guideline. J Urol 2020;204(4):778-786. https://doi.org/10.1097/JU.0000000000001297.

Barry MJ, Fowler FJ, O’Leary MP, et al. The American urological association symptom index for benign prostatic hyperplasia. J Urol 1992;148:1549.

Davis R, Jones JS, Barocas DA, et al. Diagnosis, evaluation and follow-up of asymptomatic microhematuria (AMH) in adults: AUA guideline. J Urol 2012;188: 2473-2481.

Farwell MD, Pryma DA, Mankoff DA. PET/CT imaging in cancer: current applications and future directions. Cancer 2014;120:3433-3445.

Karnofsky DA, Abelmann WH, Craver LF, et al. The use of the nitrogen mustards in the palliative treatment of carcinoma—with particular reference to bronchogenic carcinoma. Cancer, 1948;1(4):634-656.

Kriston L, Gunzler C, Harms A, et al. Confirmatory factor analysis of the German version of the international index of erectile function (IIEF): a comparison of four models. J Sex Med 2008;5:92.

52 CHAPTER 1  Evaluation of the Urologic Patient

Oken MM, Creech RH, Tormey DC, et al. Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol 1982;5(6):649-655.

Silverman SG, Pedrosa I, Ellis JH, et al. Bosniak classification of cystic renal masses, version 2019: an update proposal and needs assessment. Radiology 2019;292:475-488.

Steiner H, Bergmeister M, Verdorfer I, et al. Early results of bladder-cancer screening in a high-risk population of heavy smokers. Br J Urol 2008;102:291-296.