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DERMATOLOGY 3.001-3.003

Handbook

3.001

Basal Cell Carcinoma (BCC)

Age: usually >35 yearsMore frequent in males

Mostly on sun-exposed areas: face (mainly), neck, upper trunk, limbs

May ulcerate easily = ‘rodent ulcer’Slow-growing over years

Has various forms: nodular, pigmented, ulcerated, etc.

Does not metastasise via lymph nodes or bloodstream

Management:

Simple elliptical excision (3–4 mm margin) is best.

Photodynamic therapy—response rate is >90% for nodular and superficial BCCs.

Cryotherapy is suitable for well- defined, histologically confirmed, superficial tumours at sites away from head and neck.

Basal Cell Carcinoma (BCC)

Pearly edge

Implantation dermoid cysts

as the result of implantation of epidermal fragments into the dermis by a penetrating injury.

The epidermis continues to grow and forms a cyst lined with stratified squamous epithelium and filled with keratin

Amelanotic malignant melanoma

Amelanotic melanoma is a form of melanoma

The malignant cells have little to no pigment

Risk factors: Increasing age, Sun-exposed skin

Treatment:

wide local excision of the wound with a 10–20 mm margin of normal tissue

Amelanotic melanoma can metastasis. These cases require individualized

treatment that may include surgery,

• May present as an erythematous scaly

macule, plaque, or nodule with irregular radiotherapy, chemotherapy borders

Amelanotic malignant melanoma

External angular dermoids

Looks like subcutaneous lumps at the lateral angle of the eye

Keratoacanthoma

Tumour of keratinocytes

Occur singly on light-exposed areas

Raised crater with central keratin plug

Grows to 2 cm or more

Can be confused with SCC

Treatment is surgical excision and histological examination. Ensure a 2–3 mm margin for excision.

3.002